Job ID:
Job date: 2018-06-27
End Date: 2018-08-26
Company : Broad Institute Country : United States Role : Other
Job date: 2018-06-27
End Date: 2018-08-26
Company : Broad Institute Country : United States Role : Other
Job Description:
The Broad is looking for exceptional candidates to join the Cardiovascular Disease Initiative (CVDi) . The successful candidates will join an interdisciplinary team of computational biologists, laboratory scientists, and clinicians working together to identify and validate new molecular targets for heart disease, with the ultimate goal of advancing novel therapeutics to the clinic in collaboration with a strategic industry partner. We are currently looking for candidates to contribute to identifying new pathways for heart failure using a range of innovative technologies, principally high-resolution mapping of cardiovascular tissue via single-cell RNA sequencing. The candidates will take the lead on performing analyses of single-cell studies, prioritizing potential targets, and collaborating directly with scientists performing experimental research studies at the bench. Example workstreams include:
Additional Info:
The Broad Institute is an amazing place - we apply our deep knowledge of human genetics to empower a revolution in biomedicine and accelerate the pace at which the world conquers disease. Through our partnerships with MIT, Harvard, and the Harvard teaching hospitals, we've become a worldwide hub of cutting-edge biomedical science. The Broad was founded to explore the applications of genomic medicine, and now conducts research in infectious disease, cancer, and inherited disease, along with basic research in the life sciences. EOE / Minorities / Females / Protected Veterans / Disabilities [Click Here to Access the Original Job Post]
The Broad is looking for exceptional candidates to join the Cardiovascular Disease Initiative (CVDi) . The successful candidates will join an interdisciplinary team of computational biologists, laboratory scientists, and clinicians working together to identify and validate new molecular targets for heart disease, with the ultimate goal of advancing novel therapeutics to the clinic in collaboration with a strategic industry partner. We are currently looking for candidates to contribute to identifying new pathways for heart failure using a range of innovative technologies, principally high-resolution mapping of cardiovascular tissue via single-cell RNA sequencing. The candidates will take the lead on performing analyses of single-cell studies, prioritizing potential targets, and collaborating directly with scientists performing experimental research studies at the bench. Example workstreams include:
- Design and implement methods for single-cell analysis of biological data
- Collaborate with experimentalists and associate computational biologists to develop and apply functional genomics techniques
- Integrate single-cell data with other available genetic, sequencing, and epigenetic datasets to help prioritize potential therapeutic targets and cell types
- Collaborate with Broad Institute single-cell analysis community and Human Cell Atlas group
- Design and lead independent projects
- Create scientifically rigorous visualizations, communications, and presentations of results
- Contribute to generation of protocols, publications, and intellectual property
- Maintain and organize computational infrastructure and resources
- Ph.D. in computational biology, genetics, computer science, statistics, mathematics, molecular biology, or related field preferred, but talented applicants of all levels are encouraged to apply
- Demonstrated expertise in statistical methods in single-cell data analysis, including working knowledge of Seurat R package is preferred
- Interest in molecular biology and genomics
- Fluency in Unix, standard bioinformatics tools (Python, R, or equivalent), and a programming language (C/C++, Java)
- Track record of working on complex problems, and ability to integrate data from multiple disciplines
- Strong interpersonal, influencing, and collaboration skills to work in a team-oriented, matrix environment, and the ability to work through conflicts
- Outstanding verbal and written communication abilities
- Ability to adapt to and effectively manage changes in a fast paced and dynamic environment
- A passion for science and sense of urgency to find new medicines to benefit patient
Requeriments :
Skills :
- Bioinformatics
- genomic
- Lunix/Unix
- molecular biology
- Programing in C
- Programing in C++
- Programing in Python
- Programing Skills
- Programming in Java
- Programming in R
- Statistics
Areas :
Additional Info:
The Broad Institute is an amazing place - we apply our deep knowledge of human genetics to empower a revolution in biomedicine and accelerate the pace at which the world conquers disease. Through our partnerships with MIT, Harvard, and the Harvard teaching hospitals, we've become a worldwide hub of cutting-edge biomedical science. The Broad was founded to explore the applications of genomic medicine, and now conducts research in infectious disease, cancer, and inherited disease, along with basic research in the life sciences. EOE / Minorities / Females / Protected Veterans / Disabilities [Click Here to Access the Original Job Post]