Job Company: Karolinska Institutet
Duties: We are looking for a postdoc-level researcher to join the team at CTMR as a bioinformatician. The applicant should be able to take on a leading role in large-scale studies of the human microbiome in collaboration with external clinical researchers. The position involves bioinformatics and biostatistical analyses of large-scale DNA sequencing data. [More]
Duties: The position is for a postdoctoral fellow on salary for one year fixed term with the possibility for extension. The postdoctoral fellow will take on the processing, quality control, storage and analysis of high-throughput single-cell molecular data (methylome, transcriptome). The project is focused on investigating preimplantation development. [More]
You want to join our team as a project leader in bioinformatics? The successful candidate is expected to have a master’s degree or relevant experience in academia or industry in a suitable field (bioinformatics, computer science, mathematical modelling, statistics, or another relevant field). [More]
Are you the Senior Bioinformatician in Precision Medicine we are looking for? The successful candidate is expected to have a doctoral degree or relevant long-term experience in academia or industry in a suitable field such as bioinformatics, computer science, mathematical modelling or statistics. [More]
We are looking for an outstanding Bioinformatician with experience from analysis of omics data. The position requires solid expertise in genomics, transcriptomics and/or proteomics data analysis and communication skills as well as willingness to team work. The current position offers a great possibility for varying and developing work in an engaged group of scientists and contribute to science and medicine. [More]
Karolinska Institutet, Institutionen för odontologi The Department of Dental Medicine in Huddinge focuses on the education of dentists and dental hygienists. In addition, we perform research, dental specialization training and provide patient care by specialist dentists. Karolinska Institutet and the rest of Scandinavia have been world leaders in dentistry for decades. Division Margaret Sällberg Chen’s research group, research theme - Infection, Inflammation and Immunology. Area of responsibilities/description of work This postdoctoral research position is immediately available in the research group of Dr. Margaret Sällberg Chen. The position is for a scientist with background in disease conditions associated with dysfunctional oral microbiota. The candidate will be part of a research team that aims at understanding new mechanistic insights of in patients suffering from diseases related to infection or microbiota dysfunction and microbial translocation. The work comprises monitoring of microbiome/metabolome dynamics to study interactions between oral microbiota and pathological reactions including cancer. Disease-specific markers will be investigated to develop diagnostic methods and individualized therapeutic strategies to improve human health. The post doctoral fellows to be recruited to the project will be part of a multidisciplinary team and are expected to take active part in collaborative efforts, in line with the overall aims of this project. The studies will require methodological skills - from handling of human biopsy/biofluid to RNA/DNA purification quality controls for sequencing and metabolomics analysis. The project is suitable for highly motivated researchers in molecular life sciences, especially those who have already knowledge of NGS bioinformatics workflow and resources. Type of scholarship Karolinska Institutet awards scholarships to pursue postdoctoral studies. This educational scholarship, which is paid for a maximum of two years within four years after the receipt of a PhD or the equivalent, is tax-exempt. The amount is set for twelve months at a time and is paid out on a monthly basis. In exceptional cases, shorter periods may be acceptable. Application process An application must contain the following documents in English: Curriculum vitae and qualifications – a complete CV, including date of thesis defence, title of the thesis, previous academic positions, academic title, current positions, distinctions, student supervision and committee work. A complete list of publications A motivation letter Contact information of two references or recommendation letters. A summary of current work (no more than one page) Verifications for crediting of illness, military service, work for labour unions or student organisations, parental leave or similar circumstances Verification from the thesis defence committee or the equivalent (only if the thesis defence is scheduled within three months after the application deadline) For more information and to proceed with your application please click on the ''Apply through website'' button. [More]
Postdoctoral studies (scholarship) in computational transcriptomics and epigenomics in acute myeloid leukemia (AML). Description of project and work. This postdoc project is a collaborative project between Andreas Lennartsson’s research team at the department of Biosciences and Nutrition, Karolinska Institutet and Sören Lehmann’s group at the Institution of Medical Sciences at Uppsala University. Andreas Lennartsson’s research group is interested in the epigenetic regulation of normal myelopoiesis and acute myeloid leukemia (AML) (https://kiedit.ki.se/en/people/andlen). The aim is to identify key epigenetic factors that regulate enhancer activity and multi-potency in hematopoietic stem cells and dissect how they contribute to the development of leukemic stem cells. The group of Sören Lehmann is a translational research group focusing on AML spanning from basic science to clinical trials and both clinicians and basic researchers are active in the group. The focus is on epigenetic dysregulation in AML with an important aim to develop new treatment strategies based on epigenetic dysregulation. The Lehmann and Lennarssons’ groups are working very closely together creating an inspiring work environment containing complementary expertise. The epigenetic machinery is often perturbed in AML and contributes to leukomogenesis via different mechanisms. Increased knowledge about the aberrant epigenetic machinery will help us to better understand the mechanisms that give rise to AML. Our common research will potentially provide tools for novel therapies. This collaborative project offers you a unique possibility to analyze AML patient samples using novel state of the art methodologies. You will bridge the clinical and preclinical research at our institutes. Duties Bioinformatics is central in our research and you will work close together with other postdocs and PhD students in both groups. You will be involved in planning experiments, final analysis and visualization of the results. You will have the possibility to participate national and international collaborations. You will analyze data from multiple technology platforms that are obtained using techniques such as Chromatin Immune Precipitation (ChIP)-sequencing, RNA-seq/CAGE, ATAC-seq and Whole Genome Bisulphite sequencing. This position provides opportunity for growth and development as an independent investigator, as there will be possibilities for initiating new research directions. [More]
Karolinska Institutet is one of the world´s leading medical universities. Its mission is to contribute to the improvement of human health through research and education. Karolinska Institutet accounts for over 40 per cent of the medical academic research conducted in Sweden and offers the country´s broadest range of education in medicine and health sciences. Since 1901 the Nobel Assembly at Karolinska Institutet has selected the Nobel laureates in Physiology or Medicine. The Department of Laboratory Medicine consists of 9 divisions and is active in many areas of Laboratory Medicine. The department is involved in advanced basic scientific, clinical and epidemiological research. The department is one of the largest departments of education at Karolinska Institutet. Division The Division of Clinical Immunology conducts research on several aspects of human immunology with a strong focus on developmental immunology, immunotherapy and pathologies associated with the immune system. [More]
We are seeking a highly motivated and enthusiastic postdoctoral fellow to study large-scale single-cell transcriptome regarding regenerative mechanisms (mainly in the CNS and the pancreas), at the Department of Cell and Molecular Biology, Karolinska Institutet. The position consists of a 2 years full time stipend with a possibility of a 2 years extension. [More]
The Department of Biosciences and Nutrition performs research and education in areas of medical science including molecular endocrinology, cancer biology, functional genomics, systems biology, epigenetics, structural biochemistry, cellular virology, and nutrition [More]