The position will work in a lab focused on developing tools for the genetic analysis of the immune response. The group uses a variety of conventional and specialized in-house gene sequencing assays in biotechnology development. The candidate will work in a small team of programmers and experimental scientists in developing analysis software for a variety of immune response genotyping data sets. This role will focus on refactoring, documenting, and improving a Java codebase as well as implementing various tools in Amazon Web Services. The successful candidate must have excellent communication skills. [More]

Originally posted on 2016-12-31

System Analyst / Programmer III   Fred Hutchinson Cancer Research Center, home of three Nobel laureates, is an independent, nonprofit research institution dedicated to the development and advancement of biomedical research to eliminate cancer and other potentially fatal diseases. Recognized internationally for its pioneering work in bone-marrow transplantation, the Center's five scientific divisions collaborate to form a unique environment for conducting basic and applied science. The Hutchinson Center, in collaboration with its clinical and research partners, the University of Washington and Seattle Children's, is the only National Cancer Institute-designated comprehensive cancer center in the Pacific Northwest. Join us and make a difference! Biostatistics, Bioinformatics & Epidemiology (BBE) Program is seeking a Senior Programmer/Analsyt. The Senior Programmer/Analyst will work to advance the ImmuneSpace portal (www.immunespace.org) and its analysis framework by extending and improving its visualization and analysis capabilities, user interface and software architecture. The successful candidate will design, implement, and maintain leading-edge open-source web-based software solutions for interactive big data analysis and visualization. The Senior Programmer / Analyst will also be involved in the database design and maintenance, and the development of algorithms for processing and analyzing biological datasets. Furthermore, the Senior Programmer / Analyst will be expected to engage the ImmuneSpace user community by responding to support, maintenance, and new feature requests arising through established channels. Finally, the position candidate will be expected to participate in daily and weekly team meetings as well as to mentor junior team members. The successful candidate will design, implement, and maintain leading-edge open-source web-based software solutions for interactive big data analysis and visualization. The Senior Programmer / Analyst will also be involved in the database design and maintenance, and the development of algorithms for processing and analyzing biological datasets. Furthermore, the Senior Programmer / Analyst will be expected to engage the ImmuneSpace user community by responding to support, maintenance, and new feature requests arising through established channels. Finally, the position candidate will be expected to participate in daily and weekly team meetings as well as to mentor junior team members.  [More]

Originally posted on 2016-06-25

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch's pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation's first and largest cancer prevention research program, as well as the clinical coordinating center of the Women's Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here. The laboratory of Dr. Harlan Robins, Head of Computational Biology, is recruiting two postdoc positions funded by Stand UP 2 Cancer and the V Foundation to study the interaction between the adaptive immune system and cancer. This position will come with a competitive postdoc-level salary with great benefits for a two-year position with some possibility of extension. Fred Hutchinson Cancer Research Center, home of about 190 faculty including three Nobel laureates, is an independent, nonprofit research institution dedicated to the development and advancement of biomedical research. The environment is lively yet casual, with a strong emphasis on collaborative work. The Center is housed in a lovely campus next to Lake Union a short walk from downtown, and a slightly longer walk from the University of Washington. The position will involve technology development, algorithm creation, and applications. Primary research goals will be to develop high-throughput technologies to assess the specific immune response to cancer and to learn how the tumor evades this response and how the response can be resuscitated to effectively fight tumors.  [More]

Originally posted on 2016-06-07

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch's pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation's first and largest cancer prevention research program, as well as the clinical coordinating center of the Women's Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here. A Clinical Research Division laboratory that studies hematopoietic stem cell biology and is developing novel genetic modification strategies for stem cell gene therapies is recruiting a Research Technician II to assist with 1) the large scale production of non-infectious retroviruses (foamy virus) for gene therapy studies and 2) tracking of retrovirus integration sites in cell populations using Next-Generation Sequencing technology. The position will involve additional responsibilities, such as culture and analysis of cells infected with HIV and related viruses. This position affords the motivated technician an opportunity to develop and utilize tissue culture and virology skills, as well as molecular biology and bioinformatics skills.  [More]

Originally posted on 2016-05-24

Cures  Start Here.   At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch's pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation's first and largest cancer prevention research program, as well as the clinical coordinating center of the Women's Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here. The laboratory of Dr. Harlan Robins, Head of Computational Biology, is recruiting two postdoc positions funded by Stand UP 2 Cancer and the V Foundation to study the interaction between the adaptive immune system and cancer. This position will come with a competitive postdoc-level salary with great benefits for a two-year position with some possibility of extension. Fred Hutchinson Cancer Research Center, home of about 190 faculty including three Nobel laureates, is an independent, nonprofit research institution dedicated to the development and advancement of biomedical research. The environment is lively yet casual, with a strong emphasis on collaborative work. The Center is housed in a lovely campus next to Lake Union a short walk from downtown, and a slightly longer walk from the University of Washington. The position will involve technology development, algorithm creation, and applications. Primary research goals will be to develop high-throughput technologies to assess the specific immune response to cancer and to learn how the tumor evades this response and how the response can be resuscitated to effectively fight tumors.  [More]

Originally posted on 2016-05-07

Careers Start Here. A highly motivated post-doctoral research fellow is sought to carry out a research project in the lab of Dr. Andrew Hsieh at Fred Hutchinson Cancer Research Center in Seattle, WA. Applicants should be interested in the application of basic science and RNA biology research towards clinically intractable problems faced by cancer patients and will be expected to be scientifically intrepid. About the Hsieh Lab The primary focus of the Hsieh lab (http://research.fhcrc.org/hsieh/en.html) is to unravel the post-transcriptional mechanisms that govern the genesis and progression of epithelial malignancies. Our research seeks to understand how rogue cells co-opt the critical structure-function relationship between RNA and the protein synthesis machinery to drive specific cancer behavior at a molecular, cellular, and organismal level (Hsieh et al. Cancer Cell 2010, Hsieh et al. Nature 2012, Hsieh et al. Science Signaling 2015). We achieve this through utilizing cutting sequencing techniques and novel primary cell and animal models. Ultimately, we aim to utilize our fundamental discoveries in transnational control biology to tackle critical issues faced by cancer patients today. To be considered, candidates must have: A recent PhD, MD/PhD, or MD in a relevant biological field A strong background in RNA biology Experience with molecular and cellular biology techniques A demonstrated track record of productive research, with at least one first author paper Experience with bioinformatics is highly desirable An ability to work both independently and as part of a laboratory team Pay, Benefits, & Work Schedule: Full time position Salary DOE + excellent benefits To Apply: Please apply with a letter summarizing previous work experience, future research interests, and contact information for three professional references. If interested, please apply online via the  [More]

Originally posted on 2016-05-10

The Bioinformatics Specialist will report to the Director of the Genomics & Bioinformatics Shared Resources and will work with Fred Hutch scientists in refining computational research questions and developing analytical processes that can be applied to genomics and proteomics datasets. Further support will be provided through educational avenues, i.e., consulting and formal course offerings. [More]

Originally posted on 2016-03-21

We are looking for a Data Coordinator to join the SCHARP Laboratory Data Operations (LDO) group. Part of the SCHARP Data Management Unit (DMU), the LDO team is responsible for developing and maintaining the laboratory assay and specimen data pipelines for multiple clinical trials, pre-clinical studies and research and development projects. Primary projects include managing lab data from studies implemented by the HIV Vaccine Trials Network (HVTN), HIV Prevention Trials Network (HPTN), Microbicides Trials Network (MTN) and the Collaboration for AIDS Vaccine Discovery (CAVD). [More]

Originally posted on 2016-03-21

We are looking for an experienced, innovative and collaborative Programmer to join the SCHARP Laboratory Data Operations (LDO) group. Part of the SCHARP Data Management Unit (DMU), the LDO team is responsible for developing and maintaining the laboratory assay and specimen data pipelines for multiple clinical trials, pre-clinical studies and research and development projects. Primary projects include managing lab data from studies implemented by the HIV Vaccine Trials Network (HVTN), HIV Prevention Trials Network (HPTN), Microbicides Trials Network (MTN) and the Collaboration for AIDS Vaccine Discovery (CAVD). LDO programmers provide support for the management, quality control, reporting, and analysis of specimen and laboratory assay data by developing and maintaining code, building workflows to facilitate data submission and creating analysis datasets/reports. The incumbent will work in a team environment and is expected to communicate effectively with colleagues and be responsive to the needs of SCHARP staff as well as external collaborators as required. [More]

Originally posted on 2016-03-21

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch's pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer with minimal side effects. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation's first and largest cancer prevention research program, as well as the clinical coordinating center of the Women's Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here. A postdoctoral position is available in the Hsieh lab at the Fred Hutchinson Cancer Research Center. The core focus of the Hsieh lab is to interrogate the mechanisms by aberrant changes at the interface between mRNA and the translation apparatus governs cancer cell behavior at a molecular, cellular, and organismal level (Hsieh et al. Cancer Cell 2010, Hsieh et al. Nature 2012, Hsieh et al. Science Signaling 2015). For this position, the applicant will use primary cell culture methods, whole transcriptome ribosome profiling, and various cellular and molecular assays to study the structure-function relationship between mRNA and the translation machinery in human cancer. Applicants should be interested in the application of basic science research towards clinically intractable problems faced by cancer patients and will be expected to be scientifically intrepid. Essential Skills and Requirements: Candidates should be highly motivated with a recent Ph.D. and/or M.D. and have a strong background in RNA biology. Applicants with a bioinformatics background are also strongly encouraged to apply. Please apply with a letter summarizing previous work experience, future research interests, and contact information for three professional references. If interested, please apply online via the Apply through website button.  [More]

Originally posted on 2016-02-05