Job ID: 622293
Job date: 2017-08-25
End Date:
Company : Hubrecht Institue Country : Role : Postdoc | Student
Job date: 2017-08-25
End Date:
Company : Hubrecht Institue Country : Role : Postdoc | Student
Job Description:
We are therefore currently looking to expand our team of researchers with a talented postdoc or PhD student with a background in bioinformatics. Requirements: experience in deep-sequencing (next generation sequencing) * a good grasp of at least one data analysis language: R, python, perl * analytical skills to support genome-wide studies * a good understanding of molecular- and cell-biology Desired:
Additional Info:
"Unraveling lineage specification: novel insights from single-cell epigenomics". Description of the project: Phenotypic variation arises from the heritable acquisition of cell type-specific gene expression programs. Key in understanding cellular specification is to elucidate the epigenetic mechanism that underlies transcriptional heterogeneity. Therefore, to grasp the molecular concept behind the cellular acquisition of heritable traits it is essential to develop techniques to profile the epigenome at the single-cell level. The Kind group is pioneering single-cell epigenetics. A recent publication (Kind Cell 2015) employs single-cell DamID to map the interactions between DNA and the nuclear lamina. Currently the single-cell toolbox has been extended to include profiling different key chromatin types and histone modifications. We employ these techniques to obtain novel insight into cell-fate choice in various biological systems including organoids (cancer and wt) and mouse early embryogenesis. Our lab consists of experimental ("wet-lab") researchers, as well as computational ("dry-lab") researchers. By applying our novel single-cell approaches we generate large complex amounts of data that require clever and innovative new computational approaches. Location: Utrecht Science Park, De Uithof. Information: For additional information please contact Dr. jop kind j.kind@hubrecht.eu or visit the website www.hubrecht.eu. Interested? Please send your application including curriculum vitae and contact details of two potential references, before October 1st, 2017 to vacancies@hubrecht.eu, stating vacancy HI-2017-17 in the subject line. Any acquisition further to this advertisement will not be appreciated….[Click Here to Access the Original Job Post]
We are therefore currently looking to expand our team of researchers with a talented postdoc or PhD student with a background in bioinformatics. Requirements: experience in deep-sequencing (next generation sequencing) * a good grasp of at least one data analysis language: R, python, perl * analytical skills to support genome-wide studies * a good understanding of molecular- and cell-biology Desired:
- experience with techniques to map protein-DNA interactions (e.g. ChIPseq, DamIDseq)
- experience with high-performance computing clusters (e.g. Sun Grid Engine)
Requeriments :
Skills :
- Cell Biology
- HPC
- molecular biology
- Next Generation Sequencing
- Programing in Python
- Programming in PERL
- Programming in R
Areas :
Additional Info:
"Unraveling lineage specification: novel insights from single-cell epigenomics". Description of the project: Phenotypic variation arises from the heritable acquisition of cell type-specific gene expression programs. Key in understanding cellular specification is to elucidate the epigenetic mechanism that underlies transcriptional heterogeneity. Therefore, to grasp the molecular concept behind the cellular acquisition of heritable traits it is essential to develop techniques to profile the epigenome at the single-cell level. The Kind group is pioneering single-cell epigenetics. A recent publication (Kind Cell 2015) employs single-cell DamID to map the interactions between DNA and the nuclear lamina. Currently the single-cell toolbox has been extended to include profiling different key chromatin types and histone modifications. We employ these techniques to obtain novel insight into cell-fate choice in various biological systems including organoids (cancer and wt) and mouse early embryogenesis. Our lab consists of experimental ("wet-lab") researchers, as well as computational ("dry-lab") researchers. By applying our novel single-cell approaches we generate large complex amounts of data that require clever and innovative new computational approaches. Location: Utrecht Science Park, De Uithof. Information: For additional information please contact Dr. jop kind j.kind@hubrecht.eu or visit the website www.hubrecht.eu. Interested? Please send your application including curriculum vitae and contact details of two potential references, before October 1st, 2017 to vacancies@hubrecht.eu, stating vacancy HI-2017-17 in the subject line. Any acquisition further to this advertisement will not be appreciated….[Click Here to Access the Original Job Post]