Job Description:
SanBio is seeking a talented Scientist II to play an important role in the company’s research programs. This position will work with a small team of dedicated neuro- and cell biologists to generate gene expression profiling data instrumental in characterizing the company’s regenerative cell-based product, as well as in discovering its mechanisms of action. This position is expected to possess strong quantitative and analytical background, and demonstrate an experience with next generation RNA sequencing and the use of commercial and open-source bioinformatics software and open-source databases. At the same time, this position should possess a hands-on laboratory experience and familiarity with classical molecular biology techniques (such as RNA, DNA purification and quantification, tissue or cell sample preparation, qPCR, gel electrophoresis, etc). Familiarity with laser capture microdissection and/or single cell transcriptome analysis to allow spatial transcriptomic analysis to bridge in vivo and in vitro findings and assess global transcriptome changes at specific tissue locations is preferable; neurobiology knowledge is a plus. Independence, leadership, creativity, sharing and discussing ideas, strong analytical skills, and attention to details are expected. The incumbent in this position will be responsible for generating global gene expression data, conducting data mining, building the database, interpreting results, designing and conducting follow up studies, monitoring scientific literature and bringing new technologies in house, as well as communicating findings to the team. PRIMARY POSITION RESPONSIBILITIES
Additional Info:
The Scientist II joining the Company will make significant contribution to the ongoing scientific and clinical programs at SanBio. In doing so, s/he will work at the leading edge of translational regenerative medicine which witnesses the convergence of scientific understanding with industrial application to develop powerful new CNS patient therapies. The successful candidate will work closely with a small team of dedicated professionals. The culture is collaborative and one where team members are expected to be proactive and independent - delivering results in line with respective responsibilities. Information and details can be found on the Company website and via the following link to scientific publications: http://www.san-bio.com SanBio offers a competitive base and incentive compensation package. The Company provides an array of benefits to promote a healthy and creative work environment for its team members. SanBio is an Equal Opportunity/Affirmative Action employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, national origin, protected veteran status, or disability status. [Click Here to Access the Original Job Post]
SanBio is seeking a talented Scientist II to play an important role in the company’s research programs. This position will work with a small team of dedicated neuro- and cell biologists to generate gene expression profiling data instrumental in characterizing the company’s regenerative cell-based product, as well as in discovering its mechanisms of action. This position is expected to possess strong quantitative and analytical background, and demonstrate an experience with next generation RNA sequencing and the use of commercial and open-source bioinformatics software and open-source databases. At the same time, this position should possess a hands-on laboratory experience and familiarity with classical molecular biology techniques (such as RNA, DNA purification and quantification, tissue or cell sample preparation, qPCR, gel electrophoresis, etc). Familiarity with laser capture microdissection and/or single cell transcriptome analysis to allow spatial transcriptomic analysis to bridge in vivo and in vitro findings and assess global transcriptome changes at specific tissue locations is preferable; neurobiology knowledge is a plus. Independence, leadership, creativity, sharing and discussing ideas, strong analytical skills, and attention to details are expected. The incumbent in this position will be responsible for generating global gene expression data, conducting data mining, building the database, interpreting results, designing and conducting follow up studies, monitoring scientific literature and bringing new technologies in house, as well as communicating findings to the team. PRIMARY POSITION RESPONSIBILITIES
- Identify and establish technology that allows efficient and innovative study of mechanisms of action using preclinical samples.
- Prepare and manage sample submissions/analysis
- Analyze and interpret results,
- Conduct statistical analyses
- Prepare visual presentations of data
- Conduct validation studies using qRT-PCR
- Design and conduct follow up in depth studies of pathways.
- Monitor scientific literature and plan, discuss and implement new experiments and procedures.
- Provide supervision, training, and assistance to others when needed.
- PhD in Biological Sciences or Computational Biology with strong quantitative background, involving the analysis of large scale complex data such as next generation sequencing, microarrays, etc., with at least 2 years of experience
- The ideal candidates will have solid background in cell and molecular biology, bioinformatics and statistics
- Candidate must be able to effectively interpret the analysis results within biological context.
- Proficient with tools and open source software related to data analysis such as gene expression, pathway identification, etc.
- Frontend programing (JavaScript/HTML/CSS) is a plus
- Strong organizational skills: ability to multi-task and juggle multiple projects with timely follow-through.
- Demonstrated energy and passion; scientific curiosity. Participation in scientific discussions and exchange of ideas.
- Autonomous, self-starter interested to grow and progress in their career via delivering results; comfortable working in a changing environment.
- A quick study with good written and verbal communications and professional presentation skills and demeanor.
- An outstanding work ethic, high-integrity, team player attitude.
Requeriments :
Skills :
- Bioinformatics
- Cell Biology
- Data Mining
- Database design
- HTML
- JavaScript
- Microarray
- molecular biology
- Next Generation Sequencing
- RNA-seq
- Statistics
Areas :
Additional Info:
The Scientist II joining the Company will make significant contribution to the ongoing scientific and clinical programs at SanBio. In doing so, s/he will work at the leading edge of translational regenerative medicine which witnesses the convergence of scientific understanding with industrial application to develop powerful new CNS patient therapies. The successful candidate will work closely with a small team of dedicated professionals. The culture is collaborative and one where team members are expected to be proactive and independent - delivering results in line with respective responsibilities. Information and details can be found on the Company website and via the following link to scientific publications: http://www.san-bio.com SanBio offers a competitive base and incentive compensation package. The Company provides an array of benefits to promote a healthy and creative work environment for its team members. SanBio is an Equal Opportunity/Affirmative Action employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, national origin, protected veteran status, or disability status. [Click Here to Access the Original Job Post]