Bioinformatics Research Leader

Job ID:
Job date: 2014-10-15
End Date:

Company : Dawar Consulting Inc 

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Role : Research Scientist 


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Job Description:

Our Client is a world leader in In Vitro diagnostics (IVD) and tissue-based cancer diagnostics and a front runner in diabetes management.​ We are seeking a talented and motivated scientist to lead the analysis strategies for a range of next-generation sequencing (NGS) applications of future IVD products.​

Responsibilities:

· Lead the design and implementation of (prototype) workflows for the analysis of NGS data from a multitude of study designs, diseases areas and analyzes in a platform independent manner.​
· Serve as the subject matter expert for statistical, algorithmic and computational issues relevant to the analytical and clinical validation of NGS tests.​
· Provide bioinformatics leadership for internal R&D by engaging scientists, scoping problems, designing and implementing analysis solutions for the purpose of diagnostic product development in oncology and genetics.​
· Effectively weigh the costs and benefits of de novo implementations versus adapting publicly available software.​
· Work iteratively with stakeholders to address problems relevant to hypothesis testing and biomarker validation in a range of biological contexts.​

Qualifications:

· Comprehensive working knowledge of algorithms underlying common NGS analysis tools.​ This includes in-depth knowledge of probability and statistics (especially dynamic programming and graphical models) as demonstrated by course work.​
· A track record of solving complex biological problems as demonstrated by senior authorship in peer review publications.​
· A track record for effectively communicating and visualizing information.​
· Expert knowledge of R (Bioconductor) and a scripting language such as Python.​
· PhD in computer science, statistics or a related discipline.​
· Minimum of 5 years of post-doctoral experience in academia or industry.​
· Experience building and /​ or managing a team.​
· Must be comfortable providing leadership in a competitive landscape and operating independently with incomplete information.​

Knowledge of domain specific biological concepts and implementing potentially complex algorithmic and statistical designs.​
Comfortable managing and /​ or engaging biologists, technologists, statisticians and bioinformaticians to produce a portfolio of platform independent solutions for the next generation of IVD products.​


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