Job Description:
The US Army Engineer Research and Development Center (ERDC) has initiated a multi-year program in systems biology and toxicology, which includes the development of mechanistic mathematical models, such as toxicokinetic (TK) and toxicodynamic (TD) models, predictive of a wide variety of biological toxicity data gathered from whole-animal and cell-based assays.
Post-doctoral opportunities of 1 year, with potential for renewal for 2 additional years, are available for qualified candidates to pursue funded work to develop mechanistic mathematical models predictive of toxicological pathway response in teleost fish (e.g. fathead minnows, zebrafish) from data gathered at the genome and metabolome level; and to develop and analyze reverse-TK/TD models for several dosimetry related efforts involving the impacts of military munitions on the environment. In addition to these toxicological modeling studies, opportunities exist to investigate and improve ecotoxicological impact models for improved life-cycle assessments (LCA) of environmental contaminants.
Successful applicants will have obtained a PhD or all-but-dissertation (ABD) status in a field indicative of mathematical or computational training, such as biophysics, mathematics, chemical or biological engineering, bioinformatics, computational toxicology, among others; or will exhibit the knowledge, skills, and abilities required to develop mathematical models from underlying conceptual models. The incumbent will work with an experienced and diverse team of PhD-level scientists with expertise in theoretical physics, bioinformatics, genetics, molecular biology, and toxicology. The post-doctoral associate will be expected to publish their research in peer-reviewed journals. Salaries of qualified applicants may be expected to range from $55,000 to $80,000 USD, dependent upon experience. To obtain more information, send or email a resume/CV with a brief cover letter explaining your interests and experience to: Dr. Michael Mayo (Michael.L.Mayo@usace.army.mil), Environmental Laboratory, U.S. Army Engineer Research and Development Center, 3909 Halls Ferry Rd, Vicksburg, MS, 39180. Applicants will be evaluated by 25 February, 2015.
The Environmental Laboratory (EL) is one of seven DOD-funded laboratories within the US Army Engineer Research and Development Center, which is part of the US Army Corps of Engineers (http://www.erdc.usace.army.mil/). Successful applicants may join the Environmental Genomics and Systems Biology (EGSB) team, which seeks to better understand and predict the effects and impacts of chemical and physical stressors on a broad spectrum of animal species at the molecular and population level. EGSB team projects range from experimental studies of toxicological outcomes of military munitions on model animals to theoretical investigations of coupled dynamic interactions in the gene-regulatory networks of Escherichia coli and Saccharomyces cerevisiae. Related areas of research include the use of gene expression data for biomarker development, stressor / toxicity assessment and reverse engineering of biological networks impacted by stressors. Our ultimate goal in this work is development of predictive models that will inform if and why a stressor is harmful and what magnitude of risk is posed. Further, understanding biological networks and their control dynamics has inherent practical utility for understanding how complex systems function, and for predicting the fundamental behavior of complex engineered networks. All of these efforts include a heavy component of bioinformatics, mathematical and computational modeling, and systems biology approaches. As a result we are searching for motivated people that can not only support these existing efforts, but contribute innovative solutions that advance the USACE and EL mission.
Additional Info:
[Click Here to Access the Original Job Post]
The US Army Engineer Research and Development Center (ERDC) has initiated a multi-year program in systems biology and toxicology, which includes the development of mechanistic mathematical models, such as toxicokinetic (TK) and toxicodynamic (TD) models, predictive of a wide variety of biological toxicity data gathered from whole-animal and cell-based assays.
Post-doctoral opportunities of 1 year, with potential for renewal for 2 additional years, are available for qualified candidates to pursue funded work to develop mechanistic mathematical models predictive of toxicological pathway response in teleost fish (e.g. fathead minnows, zebrafish) from data gathered at the genome and metabolome level; and to develop and analyze reverse-TK/TD models for several dosimetry related efforts involving the impacts of military munitions on the environment. In addition to these toxicological modeling studies, opportunities exist to investigate and improve ecotoxicological impact models for improved life-cycle assessments (LCA) of environmental contaminants.
Successful applicants will have obtained a PhD or all-but-dissertation (ABD) status in a field indicative of mathematical or computational training, such as biophysics, mathematics, chemical or biological engineering, bioinformatics, computational toxicology, among others; or will exhibit the knowledge, skills, and abilities required to develop mathematical models from underlying conceptual models. The incumbent will work with an experienced and diverse team of PhD-level scientists with expertise in theoretical physics, bioinformatics, genetics, molecular biology, and toxicology. The post-doctoral associate will be expected to publish their research in peer-reviewed journals. Salaries of qualified applicants may be expected to range from $55,000 to $80,000 USD, dependent upon experience. To obtain more information, send or email a resume/CV with a brief cover letter explaining your interests and experience to: Dr. Michael Mayo (Michael.L.Mayo@usace.army.mil), Environmental Laboratory, U.S. Army Engineer Research and Development Center, 3909 Halls Ferry Rd, Vicksburg, MS, 39180. Applicants will be evaluated by 25 February, 2015.
The Environmental Laboratory (EL) is one of seven DOD-funded laboratories within the US Army Engineer Research and Development Center, which is part of the US Army Corps of Engineers (http://www.erdc.usace.army.mil/). Successful applicants may join the Environmental Genomics and Systems Biology (EGSB) team, which seeks to better understand and predict the effects and impacts of chemical and physical stressors on a broad spectrum of animal species at the molecular and population level. EGSB team projects range from experimental studies of toxicological outcomes of military munitions on model animals to theoretical investigations of coupled dynamic interactions in the gene-regulatory networks of Escherichia coli and Saccharomyces cerevisiae. Related areas of research include the use of gene expression data for biomarker development, stressor / toxicity assessment and reverse engineering of biological networks impacted by stressors. Our ultimate goal in this work is development of predictive models that will inform if and why a stressor is harmful and what magnitude of risk is posed. Further, understanding biological networks and their control dynamics has inherent practical utility for understanding how complex systems function, and for predicting the fundamental behavior of complex engineered networks. All of these efforts include a heavy component of bioinformatics, mathematical and computational modeling, and systems biology approaches. As a result we are searching for motivated people that can not only support these existing efforts, but contribute innovative solutions that advance the USACE and EL mission.
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Additional Info:
[Click Here to Access the Original Job Post]