Job ID: 2706
Job date: 2015-02-09
End Date:
Company : Josep Carreras Leukaemia Research Institute (IJC): Country : Role : Student
Job date: 2015-02-09
End Date:
Company : Josep Carreras Leukaemia Research Institute (IJC): Country : Role : Student
Job Description:
Summary:
We are a young and dynamic translational research group in iron metabolism diseases working in close collaboration with renowned international experts to improve basic knowledge in Iron diseases and discover novel iron-related entities applying the latest technology (exome/whole genome sequencing).
Our goal is to develop and apply computational technologies for iron related diseases. To this regard we have developed several projects that need to be continued incorporating a bioinformatician.
Project 1: We are analysing next-generation data from patients with novel iron-related diseases and developing and maintaining exome annotation pipelines.
Project 2: We created the bioinformatic SIREs web-server for the prediction of iron-responsive elements (http://ccbg.imppc.org/sires/). Based on new experimental data we are currently improving in this program. (1)
Project 3: We studied by computational analysis and structural modelling the effect of novel mutation in iron diseases (2)
Requisites and expected skills:
- Master finished before July 2015 and after 1-1-2011 (to be able to be admitted or provisional admitted in a PhD programme)
- Degree in Computational Biology, Molecular Biology, Computer Science or related discipline obtained after 1-1-2011.
- Basic UNIX skills and familiarity with computational environments.
- Fluency in one scripting language, such as PERL or Python, and one compiled language, such as C/C++, preferred.
- Experience with Next Generation Sequencing data analysis and/or computational structural biology will be a plus.
- A good understanding of statistics and facility with a statistical package such as R is desirable.
- Seminars of the group are in English, so a good level of English is required,
- The ability to pinpoint problems/challenges and find innovative solutions.
We are looking for someone that could start ASAP in our lab.
Please send your request to msanchez@imppc.org before February 20, 2015. Please include:
- Email Subject: Bioinformatician candidate to work as PhD student 2015
- CV with contact details
- Name, email and phone of two referees who can provide references.
- Letter of motivation
References:
1. Campillos M, Cases I, Hentze MW, Sánchez M. SIREs: Searching for Iron-Responsive Elements. Nucleic Acids Research 2010 Jul 1;38 W360-7.. IF: 7.836. Cites: 16, Q1
2. Athiyarath R, Arora N, Fuster F, Schwarzenbacher R, Ahmed R, George B, Chandy M, Srivastava A, Rojas AM, Sánchez M, Edison ES. Two Novel Missense Mutations in Iron Transport Protein Transferrin Causing Hypochromic Microcytic Anaemia and Haemosiderosis: molecular characterisation and structural implications. Brit J Haematol 2013 Nov;163(3):404
This job comes from a partnership with Science Magazine and
Additional Info:
[Click Here to Access the Original Job Post]
Summary:
We are a young and dynamic translational research group in iron metabolism diseases working in close collaboration with renowned international experts to improve basic knowledge in Iron diseases and discover novel iron-related entities applying the latest technology (exome/whole genome sequencing).
Our goal is to develop and apply computational technologies for iron related diseases. To this regard we have developed several projects that need to be continued incorporating a bioinformatician.
Project 1: We are analysing next-generation data from patients with novel iron-related diseases and developing and maintaining exome annotation pipelines.
Project 2: We created the bioinformatic SIREs web-server for the prediction of iron-responsive elements (http://ccbg.imppc.org/sires/). Based on new experimental data we are currently improving in this program. (1)
Project 3: We studied by computational analysis and structural modelling the effect of novel mutation in iron diseases (2)
Requisites and expected skills:
- Master finished before July 2015 and after 1-1-2011 (to be able to be admitted or provisional admitted in a PhD programme)
- Degree in Computational Biology, Molecular Biology, Computer Science or related discipline obtained after 1-1-2011.
- Basic UNIX skills and familiarity with computational environments.
- Fluency in one scripting language, such as PERL or Python, and one compiled language, such as C/C++, preferred.
- Experience with Next Generation Sequencing data analysis and/or computational structural biology will be a plus.
- A good understanding of statistics and facility with a statistical package such as R is desirable.
- Seminars of the group are in English, so a good level of English is required,
- The ability to pinpoint problems/challenges and find innovative solutions.
We are looking for someone that could start ASAP in our lab.
Please send your request to msanchez@imppc.org before February 20, 2015. Please include:
- Email Subject: Bioinformatician candidate to work as PhD student 2015
- CV with contact details
- Name, email and phone of two referees who can provide references.
- Letter of motivation
References:
1. Campillos M, Cases I, Hentze MW, Sánchez M. SIREs: Searching for Iron-Responsive Elements. Nucleic Acids Research 2010 Jul 1;38 W360-7.. IF: 7.836. Cites: 16, Q1
2. Athiyarath R, Arora N, Fuster F, Schwarzenbacher R, Ahmed R, George B, Chandy M, Srivastava A, Rojas AM, Sánchez M, Edison ES. Two Novel Missense Mutations in Iron Transport Protein Transferrin Causing Hypochromic Microcytic Anaemia and Haemosiderosis: molecular characterisation and structural implications. Brit J Haematol 2013 Nov;163(3):404
This job comes from a partnership with Science Magazine and
Skills :
Areas :
Additional Info:
[Click Here to Access the Original Job Post]