Bioinformatics of causative mechanism discovery using drug signatures – University of Sheffield Centre for Genome Translation, United Kingdom-Sheffield

Job Description:

ISCB Job Board

Bioinformatics of causative mechanism discovery using drug signatures University of Sheffield Centre for Genome TranslationNeuroscience and computer scienceUnited Kingdom-Sheffield Discovery of causative mechanisms for disease requires new approaches to exploit the digitally encoded information available in the growing repositories of high dimensional data for biomedical research. You will work closely with our multidisciplinary research group both at the University of Sheffield and at Harvard to develop, apply and validate novel methods for interpretation of drug induced response signatures using bioinformatics-based approaches. This innovative opportunity will exploit your skills in quantitative biology, showcasing your ability to develop methods that have high impact and show clinical and wet lab applications. You will understand the need for translation and are a highly independent researcher who wants to exploit your interest in developing new methods for challenging problems. This is a career launching post and comes at a time when the skills you will acquire will be in high demand in both academics and industry.

Working in a stimulating environment with close association with clinical and wet lab scientists, you will join a growing team in the Centre for Genome Translation working across Sheffield University’s Institute for Translational Neuroscience in the department of Neuroscience and also the department of computer sciences. You will work with datasets generated at Harvard, Sheffield and across our global consortia to exploit whole genome human variation data, gene expression, drug response, and high throughput data from the LINCS project(http://www.lincsproject.org) the NIH Advanced Medicines Partnership (http://www.nih.gov/science/amp/alzheimers.htm) , and our local teams.
You will be trained and travel to local and international meetings, and you will collaborate closely with the groups at Harvard School of Public Health, Harvard Stem Cell Institute and Biogen Idec in Cambridge, USA and Sheffield departments of Computer Sciences and Neuroscience as well as Sheffield Hospital.

Please apply by email if you are interested by March 28th. Enclose a CV and statement of research interests.  PhD
Programming/scripting, quantitative biology experience essential. This is a computational biology post only. Job Information Position Type: Post-Doctoral Research Fellowships Reference (Job ID number): Pdoc3 Start Date: ASAP Duration: Full Time Status: openContact InformationUniversity of Sheffield Centre for Genome Translation
Neuroscience and computer science
Winston Hide
winhide'at'sheffield.ac.ukhttp://sitran.dept.shef.ac.uk/people/hide/How To Apply:email

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Skills :

• Bioinformatics
• Biology
• Computational Biology

Areas :

• Bioinformatics
• Computational Biology

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Additional Info:

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