Job ID: 2782
Job date: 2015-02-18
End Date:
Company : University of Copenhagen Country : Role : Faculty
Job date: 2015-02-18
End Date:
Company : University of Copenhagen Country : Role : Faculty
Job Description:
Our research and the group
Research in the Porse group is focused on elucidating mechanisms governing normal and malignant hematopoiesis with special emphasis on the behaviour of hematopoietic stem cells during adult hematopoiesis and leukemic stem cells in acute myeloid leukemia. To this end we employ mouse models of human AML, mouse knock-out lines of key regulatory components as well as primary patient material. We have also conducted a number of shRNA-based in vivo screens for genes involved in tumor maintenance and identified a number of novel potential oncogenes and tumor suppressors, which will be studied in future projects.
The Porse group is affiliated with the Finsen Laboratory (www.finsenlab.dk) at Rigshospitalet as well as BRIC (www.bric.ku.dk) and DanStem (www.danstem.ku.dk), both University of Copenhagen.
The research project(s)
A number of projects within the overall headlines listed below are available for the successful applicants.
1. Characterisation of novel candidate oncogenes and tumor suppressors in AML
2. Development and characterisation of novel mouse models of human AML
3. Characterisation of HSC regulators
Start: Preferably Spring 2015 or after agreement.
Duration: Two positions of 3 years and two positions of 2 years.
Qualifications
We expect you to be a highly motivated and highly ambitious scientist with the following qualifications:
• A PhD in Life Sciences
• Strong documented research experience in either mouse genetics, advanced flow cytometry, chromatin immunoprecipation or functional hematopoiesis.
• Candidates with combined experiences are particularly encouraged to apply.
• Strong molecular biology background and/or experience with bioinformatics processing of NGS/micro-array datasets is an advantage
• Excellent English skills written and spoken
Additional Info:
[Click Here to Access the Original Job Post]
Our research and the group
Research in the Porse group is focused on elucidating mechanisms governing normal and malignant hematopoiesis with special emphasis on the behaviour of hematopoietic stem cells during adult hematopoiesis and leukemic stem cells in acute myeloid leukemia. To this end we employ mouse models of human AML, mouse knock-out lines of key regulatory components as well as primary patient material. We have also conducted a number of shRNA-based in vivo screens for genes involved in tumor maintenance and identified a number of novel potential oncogenes and tumor suppressors, which will be studied in future projects.
The Porse group is affiliated with the Finsen Laboratory (www.finsenlab.dk) at Rigshospitalet as well as BRIC (www.bric.ku.dk) and DanStem (www.danstem.ku.dk), both University of Copenhagen.
The research project(s)
A number of projects within the overall headlines listed below are available for the successful applicants.
1. Characterisation of novel candidate oncogenes and tumor suppressors in AML
2. Development and characterisation of novel mouse models of human AML
3. Characterisation of HSC regulators
Start: Preferably Spring 2015 or after agreement.
Duration: Two positions of 3 years and two positions of 2 years.
Qualifications
We expect you to be a highly motivated and highly ambitious scientist with the following qualifications:
• A PhD in Life Sciences
• Strong documented research experience in either mouse genetics, advanced flow cytometry, chromatin immunoprecipation or functional hematopoiesis.
• Candidates with combined experiences are particularly encouraged to apply.
• Strong molecular biology background and/or experience with bioinformatics processing of NGS/micro-array datasets is an advantage
• Excellent English skills written and spoken
Skills :
Areas :
Additional Info:
[Click Here to Access the Original Job Post]