Job ID: 3419
Job date: 2015-05-18
End Date:
Company : University of Texas Southwestern Medical Center Country : Role : Postdoc
Job date: 2015-05-18
End Date:
Company : University of Texas Southwestern Medical Center Country : Role : Postdoc
Job Description:
We are a collaborative and energetic team in the Green Center for Reproductive Biology at UT Southwestern Medical Center in Dallas, Texas. We are intensely focused on unraveling the functions of the non-coding genome, and are particularly intrigued by several questions:
• How do the millions of non-coding regulatory elements, including enhancers, promoters, insulators, and repressors, synergize to precisely control gene expression?
• How do genetic and epigenetic perturbations affect regulatory element function and contribute to disease?
• Can we build a predictive understanding of non-coding element function to learn the rules of gene regulation?
To answer these questions, we take a systems biology approach: developing and employing integrative techniques at the interface of gene regulation, epigenetics, functional genomics, and bioinformatics. Specifically, to provide a descriptive global view of gene regulation, we employ high throughput sequencing assays to interrogate the epigenome, identify regulatory elements, and probe the three-dimensional interactions of these elements with target genes. In parallel, to derive predictive models of regulatory element function, we are developing high throughput functional screens with gene editing approaches. Through integrative bioinformatic analysis, we apply these predictive models to descriptive global data to address key questions of regulatory function in developmental and disease contexts.
POSTDOCTORAL OPENING
We firmly believe that the modern biologist must be adept at experimentation as well as computation, and we are committed to training these scientists to succeed as future independent investigators.
We are seeking applicants for an integrated and dynamic postdoctoral training program studying gene regulation on a global scale. We especially value motivated, creative, adventurous, and collaborative individuals. Familiarity with statistical / machine learning methods as applied to large-scale data analysis is essential. Bench experience in molecular biology, or a strong desire to learn how to do experiments, is encouraged.
To apply, submit a CV, a brief statement of interests / accomplishments, and a list of references to Gary.Hon@utsouthwestern.edu .
Job Information
Position Type: Postdoctoral Fellow
Start Date: ASAP
Duration: Full Time
Status: open
Contact Information
University of Texas Southwestern Medical Center
Obstetrics & Gynecology
Gary Hon
Gary.Hon@utsouthwestern.eduhttp://www.honlab.org/
How To Apply:e-mail
Additional Info:
[Click Here to Access the Original Job Post]
ISCB Job Board
Postdoctoral fellow: functional and regulatory genomicsUniversity of Texas Southwestern Medical CenterObstetrics & GynecologyUSA-TX-Dallas RESEARCH INTERESTSWe are a collaborative and energetic team in the Green Center for Reproductive Biology at UT Southwestern Medical Center in Dallas, Texas. We are intensely focused on unraveling the functions of the non-coding genome, and are particularly intrigued by several questions:
• How do the millions of non-coding regulatory elements, including enhancers, promoters, insulators, and repressors, synergize to precisely control gene expression?
• How do genetic and epigenetic perturbations affect regulatory element function and contribute to disease?
• Can we build a predictive understanding of non-coding element function to learn the rules of gene regulation?
To answer these questions, we take a systems biology approach: developing and employing integrative techniques at the interface of gene regulation, epigenetics, functional genomics, and bioinformatics. Specifically, to provide a descriptive global view of gene regulation, we employ high throughput sequencing assays to interrogate the epigenome, identify regulatory elements, and probe the three-dimensional interactions of these elements with target genes. In parallel, to derive predictive models of regulatory element function, we are developing high throughput functional screens with gene editing approaches. Through integrative bioinformatic analysis, we apply these predictive models to descriptive global data to address key questions of regulatory function in developmental and disease contexts.
POSTDOCTORAL OPENING
We firmly believe that the modern biologist must be adept at experimentation as well as computation, and we are committed to training these scientists to succeed as future independent investigators.
We are seeking applicants for an integrated and dynamic postdoctoral training program studying gene regulation on a global scale. We especially value motivated, creative, adventurous, and collaborative individuals. Familiarity with statistical / machine learning methods as applied to large-scale data analysis is essential. Bench experience in molecular biology, or a strong desire to learn how to do experiments, is encouraged.
To apply, submit a CV, a brief statement of interests / accomplishments, and a list of references to Gary.Hon@utsouthwestern.edu .
Job Information
Position Type: Postdoctoral Fellow
Start Date: ASAP
Duration: Full Time
Status: open
Contact Information
University of Texas Southwestern Medical Center
Obstetrics & Gynecology
Gary Hon
Gary.Hon@utsouthwestern.eduhttp://www.honlab.org/
How To Apply:e-mail
Skills :
Areas :
Additional Info:
[Click Here to Access the Original Job Post]