Job ID: 3557
Job date: 2015-06-04
End Date:
Company : University of Copenhagen Country : Role : Student
Job date: 2015-06-04
End Date:
Company : University of Copenhagen Country : Role : Student
Job Description:
Project description
This PhD project is part of the larger MetaPig project designed to elucidate how modulations of the pig gut microbiota may increase feed efficiency and gut health. The PhD project will focus on identification of host genetic factors shaping the microbiota diversity and on genetic mechanisms and interactions between host and microbiota of importance for gut health and nutrient absorption. The project comprises two major parts. Both exploit a large cohort of pigs in which individual feed efficiency has been registered and the microbiota has been characterized via microbiome sequencing. One part is focused on next-generation RNA sequencing and Fluidigm qPCR to characterize the gut epithelium transcriptome profile. Based on this data, gene co-expression network analysis will be carried out to identify genes and major signaling pathways of importance for microbiota assembly, feed efficiency and gut health. Another part focuses on a genome wide association study to identify loci in the pig genome with effect on gut epithelium gene expression, microbiota composition, feed efficiency and gut health.
Job description
The candidate will primarily focus on:
Transcriptome and genome analysis
GWAS
RNA and DNA sequence analysis, bioinformatics
Teaching, scientific writing, information dissemination
Required qualifications
A master's in veterinary science, molecular biology or a similar subject area related to the project
Prior experience in GWAS and bioinformatics
Knowledge in animal genetics and microbiome analysis
Motivation and excellent scientific skills are essential
Good communication skills both oral and written
Fluency in English
Preferably, scientific publications documenting the above mentioned qualifications
The successful candidate is also required to be enterprising and to possess good interpersonal skills.
It is a prerequisite that the PhD candidate is enrolled as PhD Student at the Faculty of Health and Medical Sciences, University of Copenhagen, according to the rules stipulated in “Bekendtgørelse nr. 18 af 14. januar 2008 om ph.d.-graden.“
Additional Info:
[Click Here to Access the Original Job Post]
Project description
This PhD project is part of the larger MetaPig project designed to elucidate how modulations of the pig gut microbiota may increase feed efficiency and gut health. The PhD project will focus on identification of host genetic factors shaping the microbiota diversity and on genetic mechanisms and interactions between host and microbiota of importance for gut health and nutrient absorption. The project comprises two major parts. Both exploit a large cohort of pigs in which individual feed efficiency has been registered and the microbiota has been characterized via microbiome sequencing. One part is focused on next-generation RNA sequencing and Fluidigm qPCR to characterize the gut epithelium transcriptome profile. Based on this data, gene co-expression network analysis will be carried out to identify genes and major signaling pathways of importance for microbiota assembly, feed efficiency and gut health. Another part focuses on a genome wide association study to identify loci in the pig genome with effect on gut epithelium gene expression, microbiota composition, feed efficiency and gut health.
Job description
The candidate will primarily focus on:
Transcriptome and genome analysis
GWAS
RNA and DNA sequence analysis, bioinformatics
Teaching, scientific writing, information dissemination
Required qualifications
A master's in veterinary science, molecular biology or a similar subject area related to the project
Prior experience in GWAS and bioinformatics
Knowledge in animal genetics and microbiome analysis
Motivation and excellent scientific skills are essential
Good communication skills both oral and written
Fluency in English
Preferably, scientific publications documenting the above mentioned qualifications
The successful candidate is also required to be enterprising and to possess good interpersonal skills.
It is a prerequisite that the PhD candidate is enrolled as PhD Student at the Faculty of Health and Medical Sciences, University of Copenhagen, according to the rules stipulated in “Bekendtgørelse nr. 18 af 14. januar 2008 om ph.d.-graden.“
Skills :
Areas :
Additional Info:
[Click Here to Access the Original Job Post]