Job ID:
Job date: 2014-11-05
End Date:
Company : Wellcome Trust Sanger Institute Country : Role : Postdoc
Job date: 2014-11-05
End Date:
Company : Wellcome Trust Sanger Institute Country : Role : Postdoc
Job Description:
The Trynka lab at the Wellcome Trust Sanger Institute is seeking a highly-motivated researcher with strong skills in computational genomics to fill a postdoctoral fellow position to understand how genetic variants modulate the immune system and predispose to autoimmune diseases. Our research stretches from gene mapping and development of statistical methods through to functional genomics approaches to interpret the function of genetic immune variants. We are looking for an independent thinking person with a strong background in genomics and statistics to join our team and analyse a variety of large scale datasets – from RNA-seq, ChIP-seq, genotyping, and whole genome sequencing – generated from immune cells, both in house and from publically available resources.
We profile specific immune cell subtypes with genomic assays to measure the functional consequences of autoimmune disease variation. Candidates interested in gene regulation and genetics of complex-traits would be particularly well suited to this position. You must have programming skills sufficient to confidently analyse data from whole genome assays generated across thousands of individuals. The ideal candidate will have past experience working with ChIP-seq and/or RNA-seq data, an interest in immune phenotypes, and at least one first-author publication in a peer-reviewed journal.
This position offers the opportunity to work at one of the world’s leading genomic centres at the forefront of current genomic research. In addition to access to Sanger's computational resources, including a 15000+ core computational cluster (the largest in life science research in Europe) and multiple petabytes of high-speed cluster filesystems, our group also has a wet lab where we generate our own data. This provides an exciting opportunity for you to not only analyse the data but be actively involved in the planning and execution of large-scale experiments.
We are part of a dynamic and collaborative environment at the Genome Campus and, although we seek someone who can work independently, you will have the opportunity to interact with researchers across many Programmes at the Institute, and in particular with colleagues from other teams in the Computational Genomics and Human Genetics Programmes.
Postdoctoral Fellows are typically in their first or second postdoctoral position as part of a period of early career research training.
To submit an application, please click the "Apply through website" button.
Desired skills and experience
Essential Skills
•PhD in a relevant subject area (e.g. Statistics, Computational Biology, Population Genetics/Genomics, Computer Science, Physics).
•High self-motivation and critical thinking skills.
•Strong statistical skills (significance tests, statistical distributions, fitting of statistical models).
•Proficient programming skills (e.g. Python, Perl).
•Extensive experience with command-line UNIX/Linux and cluster computing.
•Experience with analysis of large genomic data sets (e.g. data from hundreds of samples from next-generation sequencing assays).
•Ability to communicate ideas and results effectively.
•Ability to work independently and organise own workload.
•Excellent written and spoken English.
•The ability to effectively communicate with collaborators and occasionally present orally to large groups.
•Proven independent working style, problem solving, data analysis and generation of novel ideas.
Ideal Skills
•Experience with analysis of -omics data sets (e.g. RNA-seq, ChIP-seq, or DNase I, genotyping or whole genome/exome sequence).
•Previous experience with QTL analysis.
•Previous experience with human genetics data.
•Interest in/knowledge of the function of human immune system.
•Strong publishing record.
About the employer
The Sanger Institute is a charitably funded research centre focused on understanding the role of genetics in health and disease. We use state of the art large-scale genomic approaches to drive world-leading projects to uncover the basis of genetic and infectious disease. Our goal is to provide results that can be translated into diagnostics, treatments or therapies that reduce global health burdens.
The Institute is located near Cambridge, UK on the stunning Wellcome Trust Genome Campus. This growing and dynamic site is the British hub of genomic science. It hosts the European Bioinformatics Institute (EBI), the Centre for Therapeutic Target Validation, a Biodata Innovation Centre and will soon host Genomics England Limited’s 100,000 Genomes Sequencing Centre. It is an excellent environment in which to work and collaborate with researchers on campus and around the world and benefit from cross-fertilisation of ideas.
To help researchers to develop their skills and networks, the Institute hosts a range of scientific seminars with internal and invited speakers, scientific group meetings and skills development workshops. In addition the Campus is home to the Wellcome Trust Advanced Course and Scientific Conferences programme and the Wellcome Trust Conference Centre.
Our Benefits include: Defined Benefit Pension Scheme, Group Income Protection, Healthcare scheme, Childcare Vouchers, Nursery and 25 days Annual Leave plus Bank Holidays. We also have a gym, two cafes, a nursery, dining facilities, and a free campus Bus service. Our thriving Sports and Social Club provides many opportunities to meet with people working across the campus.
Additional Info:
[Click Here to Access the Original Job Post]
The Trynka lab at the Wellcome Trust Sanger Institute is seeking a highly-motivated researcher with strong skills in computational genomics to fill a postdoctoral fellow position to understand how genetic variants modulate the immune system and predispose to autoimmune diseases. Our research stretches from gene mapping and development of statistical methods through to functional genomics approaches to interpret the function of genetic immune variants. We are looking for an independent thinking person with a strong background in genomics and statistics to join our team and analyse a variety of large scale datasets – from RNA-seq, ChIP-seq, genotyping, and whole genome sequencing – generated from immune cells, both in house and from publically available resources.
We profile specific immune cell subtypes with genomic assays to measure the functional consequences of autoimmune disease variation. Candidates interested in gene regulation and genetics of complex-traits would be particularly well suited to this position. You must have programming skills sufficient to confidently analyse data from whole genome assays generated across thousands of individuals. The ideal candidate will have past experience working with ChIP-seq and/or RNA-seq data, an interest in immune phenotypes, and at least one first-author publication in a peer-reviewed journal.
This position offers the opportunity to work at one of the world’s leading genomic centres at the forefront of current genomic research. In addition to access to Sanger's computational resources, including a 15000+ core computational cluster (the largest in life science research in Europe) and multiple petabytes of high-speed cluster filesystems, our group also has a wet lab where we generate our own data. This provides an exciting opportunity for you to not only analyse the data but be actively involved in the planning and execution of large-scale experiments.
We are part of a dynamic and collaborative environment at the Genome Campus and, although we seek someone who can work independently, you will have the opportunity to interact with researchers across many Programmes at the Institute, and in particular with colleagues from other teams in the Computational Genomics and Human Genetics Programmes.
Postdoctoral Fellows are typically in their first or second postdoctoral position as part of a period of early career research training.
To submit an application, please click the "Apply through website" button.
Desired skills and experience
Essential Skills
•PhD in a relevant subject area (e.g. Statistics, Computational Biology, Population Genetics/Genomics, Computer Science, Physics).
•High self-motivation and critical thinking skills.
•Strong statistical skills (significance tests, statistical distributions, fitting of statistical models).
•Proficient programming skills (e.g. Python, Perl).
•Extensive experience with command-line UNIX/Linux and cluster computing.
•Experience with analysis of large genomic data sets (e.g. data from hundreds of samples from next-generation sequencing assays).
•Ability to communicate ideas and results effectively.
•Ability to work independently and organise own workload.
•Excellent written and spoken English.
•The ability to effectively communicate with collaborators and occasionally present orally to large groups.
•Proven independent working style, problem solving, data analysis and generation of novel ideas.
Ideal Skills
•Experience with analysis of -omics data sets (e.g. RNA-seq, ChIP-seq, or DNase I, genotyping or whole genome/exome sequence).
•Previous experience with QTL analysis.
•Previous experience with human genetics data.
•Interest in/knowledge of the function of human immune system.
•Strong publishing record.
About the employer
The Sanger Institute is a charitably funded research centre focused on understanding the role of genetics in health and disease. We use state of the art large-scale genomic approaches to drive world-leading projects to uncover the basis of genetic and infectious disease. Our goal is to provide results that can be translated into diagnostics, treatments or therapies that reduce global health burdens.
The Institute is located near Cambridge, UK on the stunning Wellcome Trust Genome Campus. This growing and dynamic site is the British hub of genomic science. It hosts the European Bioinformatics Institute (EBI), the Centre for Therapeutic Target Validation, a Biodata Innovation Centre and will soon host Genomics England Limited’s 100,000 Genomes Sequencing Centre. It is an excellent environment in which to work and collaborate with researchers on campus and around the world and benefit from cross-fertilisation of ideas.
To help researchers to develop their skills and networks, the Institute hosts a range of scientific seminars with internal and invited speakers, scientific group meetings and skills development workshops. In addition the Campus is home to the Wellcome Trust Advanced Course and Scientific Conferences programme and the Wellcome Trust Conference Centre.
Our Benefits include: Defined Benefit Pension Scheme, Group Income Protection, Healthcare scheme, Childcare Vouchers, Nursery and 25 days Annual Leave plus Bank Holidays. We also have a gym, two cafes, a nursery, dining facilities, and a free campus Bus service. Our thriving Sports and Social Club provides many opportunities to meet with people working across the campus.
Requeriments :
Skills :
Areas :
Additional Info:
[Click Here to Access the Original Job Post]