Job Description:
Exploratory Statistics and Bioinformatics is part of the Data and Statistical Sciences (DSS) organization in AbbVie R&D. This group provides statistical and bioinformatics expertise globally for various groups in drug discovery, development sciences and for biomarker studies in early to late stage clinical trials. Examples of
applications/topics supported include in-vitro screening, in-vivo pharmacology, genomics (high-throughput mRNA expression arrays, CGH arrays, next generation sequencing, microRNA, genotype data, etc.), proteomics, imaging, and other biomarker data generated from pre-clinical and clinical studies, research and
GLP assays used for measuring biomarkers, pharmacokinetics and immunogenicity response in preclinical and clinical studies, and ADMET screening assays. We have an exciting opportunity for a senior level computational biologist (grade level and position title commensurate with experience) reporting to the Global Head, Exploratory Statistics & Bioinformatics, and embedded with the scientific collaborators. This position will be based in Worcester, MA.
Key Responsibilities
Help build bioinformatics capabilities in the Immunology Translational Research & Investigation Unit by providing strategic input and leadership to analyze complex data sets derived from patient samples and pre-clinical models of disease to support novel target identification and patient stratification strategies. Sources of data will likely include: Genomics (high throughput gene expression arrays, CGH arrays, next generation sequencing, microRNA, etc.), Proteomics, Imaging, and flow based cytometric assays.
Develop and maintain good working relationships with Discovery and Clinical Scientists, statisticians,bioinformaticians, and external collaborators to drive program decisions as part of a multidisciplinaryteam.
Maintain and expand expertise in various bioinformatics and computing tools to leverage internal and external data sets to drive decisions. Examples of such tools include IPA, KEGG, GeneGo, GSEA, Cytoscape, Neato, Omnigraph, Grail, David, Panther, BLAST, etc.), in addition to R/Bioconductor, Spotfire, UNIX utilities, JAVA, Perl, etc. Continue development of various analysis tools to improve the process.
Consult/collaborate with other computational biologists and statisticians on developing and improving various analysis methodologies.
Proactively seek input and review from other experts within and outside the group on various projects and research activities, and share technical information when appropriate.
Proactively propose opportunities for productivity improvements and implementation plans.
AbbVie (NYSE:ABBV) is a global, research-based biopharmaceutical company formed in 2013 following separation from Abbott Laboratories.
Job Classification
Experienced
Shift
Day
Travel
Yes, 10 % of the Time
Position will be hired based on experience.
Basic Qualifications
5-15 years of related experience with demonstrated skills/accomplishments. Grade level and title will be commensurate with experience. Ph.D. in computational biology, statistical genetics, bioinformatics and related disciplines, with some coursework/experience in biochemistry, genetics, human physiology and related subjects.
Expertise in genetic and genomic data analysis, disease and biological pathway and network analysis.
Expertise in statistical methodologies such as predictive modeling, machine learning methods, mixed effects models, multivariate analysis, etc.
Relevant academic/industry experience on topics related to drug discovery, genomics and other applications mentioned above.
Strong programming and computing skills, along with expertise in various bioinformatics tools such as those listed above.
Key Leadership Competencies
Builds strong relationships with peers and cross functionally with partners outside of team to enable higher performance
Learns fast, grasps the 'essence' and can change the course quickly where indicated
Raises the bar and is never satisfied with the status quo
Creates a learning environment, opens to suggestions and experimentation for improvement
Embraces the ideas of others, nurtures innovation and manages innovation to reality
Additional Info:
[Click Here to Access the Original Job Post]
Exploratory Statistics and Bioinformatics is part of the Data and Statistical Sciences (DSS) organization in AbbVie R&D. This group provides statistical and bioinformatics expertise globally for various groups in drug discovery, development sciences and for biomarker studies in early to late stage clinical trials. Examples of
applications/topics supported include in-vitro screening, in-vivo pharmacology, genomics (high-throughput mRNA expression arrays, CGH arrays, next generation sequencing, microRNA, genotype data, etc.), proteomics, imaging, and other biomarker data generated from pre-clinical and clinical studies, research and
GLP assays used for measuring biomarkers, pharmacokinetics and immunogenicity response in preclinical and clinical studies, and ADMET screening assays. We have an exciting opportunity for a senior level computational biologist (grade level and position title commensurate with experience) reporting to the Global Head, Exploratory Statistics & Bioinformatics, and embedded with the scientific collaborators. This position will be based in Worcester, MA.
Key Responsibilities
Help build bioinformatics capabilities in the Immunology Translational Research & Investigation Unit by providing strategic input and leadership to analyze complex data sets derived from patient samples and pre-clinical models of disease to support novel target identification and patient stratification strategies. Sources of data will likely include: Genomics (high throughput gene expression arrays, CGH arrays, next generation sequencing, microRNA, etc.), Proteomics, Imaging, and flow based cytometric assays.
Develop and maintain good working relationships with Discovery and Clinical Scientists, statisticians,bioinformaticians, and external collaborators to drive program decisions as part of a multidisciplinaryteam.
Maintain and expand expertise in various bioinformatics and computing tools to leverage internal and external data sets to drive decisions. Examples of such tools include IPA, KEGG, GeneGo, GSEA, Cytoscape, Neato, Omnigraph, Grail, David, Panther, BLAST, etc.), in addition to R/Bioconductor, Spotfire, UNIX utilities, JAVA, Perl, etc. Continue development of various analysis tools to improve the process.
Consult/collaborate with other computational biologists and statisticians on developing and improving various analysis methodologies.
Proactively seek input and review from other experts within and outside the group on various projects and research activities, and share technical information when appropriate.
Proactively propose opportunities for productivity improvements and implementation plans.
AbbVie (NYSE:ABBV) is a global, research-based biopharmaceutical company formed in 2013 following separation from Abbott Laboratories.
Job Classification
Experienced
Shift
Day
Travel
Yes, 10 % of the Time
Position will be hired based on experience.
Basic Qualifications
5-15 years of related experience with demonstrated skills/accomplishments. Grade level and title will be commensurate with experience. Ph.D. in computational biology, statistical genetics, bioinformatics and related disciplines, with some coursework/experience in biochemistry, genetics, human physiology and related subjects.
Expertise in genetic and genomic data analysis, disease and biological pathway and network analysis.
Expertise in statistical methodologies such as predictive modeling, machine learning methods, mixed effects models, multivariate analysis, etc.
Relevant academic/industry experience on topics related to drug discovery, genomics and other applications mentioned above.
Strong programming and computing skills, along with expertise in various bioinformatics tools such as those listed above.
Key Leadership Competencies
Builds strong relationships with peers and cross functionally with partners outside of team to enable higher performance
Learns fast, grasps the 'essence' and can change the course quickly where indicated
Raises the bar and is never satisfied with the status quo
Creates a learning environment, opens to suggestions and experimentation for improvement
Embraces the ideas of others, nurtures innovation and manages innovation to reality
Skills :
Areas :
Additional Info:
[Click Here to Access the Original Job Post]