Job Description:
Erasmus MC, Department of Genetic Identification plans to appoint a Ph.D. Student for fundamental & applied research on lifestyle epigenetics with medical relevance and forensic applications. Job description The field of forensic epigenetics, mostly via investigating differential DNAmethylation patterns depending on age (Zbie´c-Piekarska et al., Forensic Sci Int Genet, 2015) or tissue type (Bartling et al., Electrophoresis, 2014), has gained increasing attention over the recent years. However, it is evident that various environmental factors including lifestyle choices impact on DNA methylation patterns such as tobacco smoking (Dogan et al., BMC Genomics, 2014), physical exercise (Voisin et al., Acta Physiologica, 2015) and others. Currently published studies in lifestyle epigenetics have mainly focused on either investigating DNAmethylation changes as a result of a lifestyle adaptation or how these lifestyle factors can affect the aging process. Information on an individual’s lifestyle profile cannot only have medical relevance but could also potentially assist in forensic intelligence investigations; however, current possibilities in predicting such information from biological samples are limited. As Ph.D. student you will investigate lifestyle dependent epigenetic variation of potential medical and forensic relevance, and you will develop and validate state-of-the-art tools for the estimation of such traits in future practical applications. This position entails close collaborative and interdisciplinary work involving other departments at Erasmus MC and international partners. For fulfilling PhD requirements at Erasmus MC, multiple first author publications in international peer-reviewed scientific journals are necessary. Work environment A healthy population and excellence in healthcare through research and education. This is what Erasmus MC stands for. Conducting groundbreaking work, pushing boundaries and leading the way. In research, education, and healthcare. We are practical people with a high level of expertise, working hard to improve and renew the healthcare of today and the public health of tomorrow. The vision of the Department of Genetic Identification (previously known as Department of Forensic Molecular Biology, http://www.erasmusmc. nl/fmb) is to improve safety of the society and enhance quality of life via outcomes of fundamental and applied research in human genetics and genomics. Using genetic identification as key principle, we perform innovative research and technological developments in a wide range of societally relevant areas of human life sciences, including forensic and legal medicine problems, epidemiological and other disease-related issues, and others. Together with several fundamental research departments, the Department of Genetic Identification is embedded in the Biomedical Science Theme (http://www.erasmusmc.nl/biomedicalsciences/?lang=en), and collaborates with several clinical departments of Erasmus MC and research institutions worldwide. Qualifications and skills You have a MSc in Molecular Biology/ Biochemistry/ Genetics from an internationally highly recognized university. You have a background in both wetlab and drylab epigenetic research and good biostatistics and bioinformatics skills. You are highly motivated to perform molecular research, you are able to develop innovative ideas within the framework of the given project, have very good communication skills in English (written and spoken language, English is the working language in the department), and you are able to work independently as well as in a team. Being able to present a certificate of good conduct is a condition for the appointment. Terms of employment You will receive a temporary position for 4 years. The gross monthly salary is € 2.222,- in the 1st year and increases to € 2.846,- in the 4th year (scale OIO). The terms of employment are according to the Collective Bargaining Agreement for Dutch University Medical Centers (CAO UMC). Information For more information about this position, please contact Prof.Dr. Manfred Kayser, e-mail:m.kayser@erasmusmc.nl. Application Applications should include CV, cover letter stating motivations, research ideas on the above mentioned topic and respectively suitable skills, list of publications if available, and names/ contact details of three senior scientists to be contacted for recommendations. No agencies please
Additional Info:
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Erasmus MC, Department of Genetic Identification plans to appoint a Ph.D. Student for fundamental & applied research on lifestyle epigenetics with medical relevance and forensic applications. Job description The field of forensic epigenetics, mostly via investigating differential DNAmethylation patterns depending on age (Zbie´c-Piekarska et al., Forensic Sci Int Genet, 2015) or tissue type (Bartling et al., Electrophoresis, 2014), has gained increasing attention over the recent years. However, it is evident that various environmental factors including lifestyle choices impact on DNA methylation patterns such as tobacco smoking (Dogan et al., BMC Genomics, 2014), physical exercise (Voisin et al., Acta Physiologica, 2015) and others. Currently published studies in lifestyle epigenetics have mainly focused on either investigating DNAmethylation changes as a result of a lifestyle adaptation or how these lifestyle factors can affect the aging process. Information on an individual’s lifestyle profile cannot only have medical relevance but could also potentially assist in forensic intelligence investigations; however, current possibilities in predicting such information from biological samples are limited. As Ph.D. student you will investigate lifestyle dependent epigenetic variation of potential medical and forensic relevance, and you will develop and validate state-of-the-art tools for the estimation of such traits in future practical applications. This position entails close collaborative and interdisciplinary work involving other departments at Erasmus MC and international partners. For fulfilling PhD requirements at Erasmus MC, multiple first author publications in international peer-reviewed scientific journals are necessary. Work environment A healthy population and excellence in healthcare through research and education. This is what Erasmus MC stands for. Conducting groundbreaking work, pushing boundaries and leading the way. In research, education, and healthcare. We are practical people with a high level of expertise, working hard to improve and renew the healthcare of today and the public health of tomorrow. The vision of the Department of Genetic Identification (previously known as Department of Forensic Molecular Biology, http://www.erasmusmc. nl/fmb) is to improve safety of the society and enhance quality of life via outcomes of fundamental and applied research in human genetics and genomics. Using genetic identification as key principle, we perform innovative research and technological developments in a wide range of societally relevant areas of human life sciences, including forensic and legal medicine problems, epidemiological and other disease-related issues, and others. Together with several fundamental research departments, the Department of Genetic Identification is embedded in the Biomedical Science Theme (http://www.erasmusmc.nl/biomedicalsciences/?lang=en), and collaborates with several clinical departments of Erasmus MC and research institutions worldwide. Qualifications and skills You have a MSc in Molecular Biology/ Biochemistry/ Genetics from an internationally highly recognized university. You have a background in both wetlab and drylab epigenetic research and good biostatistics and bioinformatics skills. You are highly motivated to perform molecular research, you are able to develop innovative ideas within the framework of the given project, have very good communication skills in English (written and spoken language, English is the working language in the department), and you are able to work independently as well as in a team. Being able to present a certificate of good conduct is a condition for the appointment. Terms of employment You will receive a temporary position for 4 years. The gross monthly salary is € 2.222,- in the 1st year and increases to € 2.846,- in the 4th year (scale OIO). The terms of employment are according to the Collective Bargaining Agreement for Dutch University Medical Centers (CAO UMC). Information For more information about this position, please contact Prof.Dr. Manfred Kayser, e-mail:m.kayser@erasmusmc.nl. Application Applications should include CV, cover letter stating motivations, research ideas on the above mentioned topic and respectively suitable skills, list of publications if available, and names/ contact details of three senior scientists to be contacted for recommendations. No agencies please
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