Job ID: 11598
Job date: 2016-06-21
End Date:
Company : The Genome Analysis Centre (TGAC) Country : Role : Postdoc
Job date: 2016-06-21
End Date:
Company : The Genome Analysis Centre (TGAC) Country : Role : Postdoc
Job Description:
* Set up informatics pipelines, tested and implemented in the iPlant environment. Developing pipelines * Genetic variation of the wheat genome’s genic space and chloroplast genome across ~500 lines * Use GWA to identify genomic regions associated with enhanced photosynthetic efficiency * Develop bioinformatics to analyse epigenetic variation in traits * Develop mapping-by-sequencing approaches and other bulk segregation analysis methods DepartmentOrganisms and EcosystemsGroup DetailsTBCAdvert TextPostdoctoral Researcher – Wheat Genomics/Quantitative Genetics Starting salary range: £30,500 - £33,750 per annum (depending on skills and experience) Duration: 3 years Location: Norwich, UK Reference: 1003059 We currently have an exciting opportunity within our Plant Genomics Group, which will involve playing a key role in an International research grant entitled, “Using Next Generation Genetic Approaches to Exploit Phenotypic Variation in Photosynthetic Efficiency to Increase Wheat Yield”. The project is led by Professor Anthony Hall, in collaboration with the University of Lancaster, CiMMYT in Mexico, and Australian National University. This $2.0M project is funded as part of International Wheat Yield Partnership. The project aims to characterise photosynthetic traits from diverse lines of wheat and combine this with quantitative genetics and next generation DNA sequencing to identify the genes associated with each trait. The role in Norwich will be to lead the genotype and genetic analysis component of the project. You will have a PhD in Biological Science with a focus on Computational Biology, Plant biology or Genetics, or related field. Experience in quantitative genetics and/or next generation sequence data analysis, excellent written and verbal communication skills and the ability to work independently are essential. With an understanding Arabidopsis or wheat genetics desirable. TGAC is a vibrant, contemporary research institute and a UK hub for innovative Bioinformatics through research, analysis and interpretation of data sets. We host one of the largest computing hardware facilities dedicated to life science research in Europe and our aim is to ensure that biological science in the UK has access to a skill base in genomics and bioinformatics to deliver programmes leading to improved food security, advances in industrial biotechnology and improved human health and wellbeing. At TGAC we offer competitive salaries, excellent defined contribution pension scheme, life assurance, tailored learning and development and onsite sports facilities that are available to all staff and their guests. As a user of the disability symbol, we guarantee to interview all disabled applicants who meet the minimum essential criteria for this vacancy. Key relationshipsINTERNAL: Head of Plant Genomics, TGAC’s Deputy Directors, Director and Senior Management Team. TGAC’s Science Faculty and Research Teams (specifically professor Hall’s team). EXTERNAL: The International Wheat Yield Programme Teams, Programme Manager and Director, other stakeholders (BBSRC, industry). Main Activities & ResponsibilitiesEstablish a diversity panel, score for key traits associated with photosynthetic efficiency and wheat yield at CIMMYT sites in Mexico.Genotype the diversity panel, using a refined wheat exome capture with ~ 500 lines.Combine photosynthetic efficiency measurements /genotypic data in a genome wide analysis (GWAS).Develop shared informatics resources for both phenotypic and bioinformatics data.Extensive physiological characterisation of a subset of wheat lines displaying enhanced yield /photosynthetic efficiency from our diversity panel and existing national panels.Use next generation genetic approaches to identify genes/markers underlying known traits using DH populations, elite mapping populations and pooled phenotypic tails from diversity panels.Validate SNP markers through initial introgression into elite material.
Education & QualificationsRequirementImportancePhD in biological science with a focus on computational biology, plant science genetics, or related subject.Essential
Specialist Knowledge & SkillsRequirementImportancePerforming and interpreting GWAEssentialNext generation sequence analysisEssentialSkills in building bioinformatics workflowsDesirableExperience using cloud computing ie iplantDesirableKnowledge of sequence data handlingDesirable
Relevant ExperienceRequirementImportanceExperience in quantitative genetic/GWAEssentialExperience of writing papersDesirableExperience in collaborating with group in the UK or International research groupsDesirableExperience in computational biology as associated with next generation sequence analysis or related subjectDesirable
Interpersonal & Communication SkillsRequirementImportanceGood presentation skillsEssentialGood interpersonal skillsEssentialAble to work independently as well as part of a teamEssentialHighly organisedEssentialAble to deal effectively with international and national collaborationsDesirable
Additional RequirementsRequirementImportancePromotes equality and values diversityEssential
Additional Info:
[Click Here to Access the Original Job Post]
* Set up informatics pipelines, tested and implemented in the iPlant environment. Developing pipelines * Genetic variation of the wheat genome’s genic space and chloroplast genome across ~500 lines * Use GWA to identify genomic regions associated with enhanced photosynthetic efficiency * Develop bioinformatics to analyse epigenetic variation in traits * Develop mapping-by-sequencing approaches and other bulk segregation analysis methods DepartmentOrganisms and EcosystemsGroup DetailsTBCAdvert TextPostdoctoral Researcher – Wheat Genomics/Quantitative Genetics Starting salary range: £30,500 - £33,750 per annum (depending on skills and experience) Duration: 3 years Location: Norwich, UK Reference: 1003059 We currently have an exciting opportunity within our Plant Genomics Group, which will involve playing a key role in an International research grant entitled, “Using Next Generation Genetic Approaches to Exploit Phenotypic Variation in Photosynthetic Efficiency to Increase Wheat Yield”. The project is led by Professor Anthony Hall, in collaboration with the University of Lancaster, CiMMYT in Mexico, and Australian National University. This $2.0M project is funded as part of International Wheat Yield Partnership. The project aims to characterise photosynthetic traits from diverse lines of wheat and combine this with quantitative genetics and next generation DNA sequencing to identify the genes associated with each trait. The role in Norwich will be to lead the genotype and genetic analysis component of the project. You will have a PhD in Biological Science with a focus on Computational Biology, Plant biology or Genetics, or related field. Experience in quantitative genetics and/or next generation sequence data analysis, excellent written and verbal communication skills and the ability to work independently are essential. With an understanding Arabidopsis or wheat genetics desirable. TGAC is a vibrant, contemporary research institute and a UK hub for innovative Bioinformatics through research, analysis and interpretation of data sets. We host one of the largest computing hardware facilities dedicated to life science research in Europe and our aim is to ensure that biological science in the UK has access to a skill base in genomics and bioinformatics to deliver programmes leading to improved food security, advances in industrial biotechnology and improved human health and wellbeing. At TGAC we offer competitive salaries, excellent defined contribution pension scheme, life assurance, tailored learning and development and onsite sports facilities that are available to all staff and their guests. As a user of the disability symbol, we guarantee to interview all disabled applicants who meet the minimum essential criteria for this vacancy. Key relationshipsINTERNAL: Head of Plant Genomics, TGAC’s Deputy Directors, Director and Senior Management Team. TGAC’s Science Faculty and Research Teams (specifically professor Hall’s team). EXTERNAL: The International Wheat Yield Programme Teams, Programme Manager and Director, other stakeholders (BBSRC, industry). Main Activities & ResponsibilitiesEstablish a diversity panel, score for key traits associated with photosynthetic efficiency and wheat yield at CIMMYT sites in Mexico.Genotype the diversity panel, using a refined wheat exome capture with ~ 500 lines.Combine photosynthetic efficiency measurements /genotypic data in a genome wide analysis (GWAS).Develop shared informatics resources for both phenotypic and bioinformatics data.Extensive physiological characterisation of a subset of wheat lines displaying enhanced yield /photosynthetic efficiency from our diversity panel and existing national panels.Use next generation genetic approaches to identify genes/markers underlying known traits using DH populations, elite mapping populations and pooled phenotypic tails from diversity panels.Validate SNP markers through initial introgression into elite material.
Education & QualificationsRequirementImportancePhD in biological science with a focus on computational biology, plant science genetics, or related subject.Essential
Specialist Knowledge & SkillsRequirementImportancePerforming and interpreting GWAEssentialNext generation sequence analysisEssentialSkills in building bioinformatics workflowsDesirableExperience using cloud computing ie iplantDesirableKnowledge of sequence data handlingDesirable
Relevant ExperienceRequirementImportanceExperience in quantitative genetic/GWAEssentialExperience of writing papersDesirableExperience in collaborating with group in the UK or International research groupsDesirableExperience in computational biology as associated with next generation sequence analysis or related subjectDesirable
Interpersonal & Communication SkillsRequirementImportanceGood presentation skillsEssentialGood interpersonal skillsEssentialAble to work independently as well as part of a teamEssentialHighly organisedEssentialAble to deal effectively with international and national collaborationsDesirable
Additional RequirementsRequirementImportancePromotes equality and values diversityEssential
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Additional Info:
[Click Here to Access the Original Job Post]