Job date: 2016-08-25
End Date:
Company : The Francis Crick Institute Country : Role : Postdoc
Postdoctoral Training Fellow in Cell Biology of Biological Clocks The Francis Crick Institute Location: London Salary: Competitive with benefits, subject to skills and experience Hours: Full Time Contract Type: Contract / Temporary Placed on: 26th August 2016 Closes: 25th September 2016 Job Ref: 3522 ★ View Employer Profile
Contract: Full- time, fixed-Term (4 years)
Short Introduction/Summary
This is an exciting role at a fresh and pioneering biomedical research institute, dedicated to innovation and science. We are looking for a highly motivated and adaptable cell biologist.
You will be highly skilled in the use of live cell imaging techniques and quantitative fluorescence microscopy. You will also be comfortable handling large imaging datasets and performing automated analysis of these using various open source and commercial software. You will be highly competent with the use of computers and technology, and have at least some experience of programming and scripting languages such as Java and R.
The Francis Crick Institute (the Crick) is a registered charity whose purpose is to conduct biomedical research into all aspects of human health and disease. Dedicated to research excellence, the institute will be a world-leading centre of biomedical research and innovation.
Project Scope/ Description
The project will focus on using novel real-time fluorescent reporters to simultaneously track 24 hour transcriptional oscillations and metabolic oscillations (e.g. hydrogen peroxide, NAD/NADH) in cells and organotypic slice culture systems. By employing CRISPR/Cas9 technology, relevant genes will be knocked out (or point mutations made) to allow mechanistic determination of links between transcriptional and metabolic processes. Some experiments will also focus on non-transcriptional oscillations in non-nucleated cells (red blood cells).
If you are interested in applying for this role, please apply via our website https://jobs.crick.ac.uk/
Please note: all offers of employment are subject to successful security screening and continuous eligibility to work in the United Kingdom.
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Academic or ResearchSubject Area(s):
Biological Sciences Biology Genetics Microbiology Molecular Biology and Biophysics Other Biological SciencesLocation(s):
London
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