Job ID: 6169
Job date: 2017-06-03
End Date:
Company : Case Western Reserve University Country : Role : Research Scientist
Job date: 2017-06-03
End Date:
Company : Case Western Reserve University Country : Role : Research Scientist
Job Description:
Working under the supervision of the principal investigator, the Senior Genome Research Assistant will manage projects and design and perform genomic and RNA-Seq experiments with a high degree of independence and assist in analysis. The individual will also communicate directly with the principal investigator and collaborators to facilitate engagement of the principal investigator’s functional genomics laboratory in the completion of projects. ESSENTIAL FUNCTIONS 1. Design, manage, perform and analyze genomic and transcriptomic experiments (e.g. exome, microbiome, RNA-Seq, miRNA-Seq) experiments with a high degree of independence. (25%) 2. Provide supervision, technical guidance and training of technical staff developing novel low-input (including single cell) protocols in next generation sequencing and bioinformatic analysis of the human and macaque genome and transcriptome. (20%) 3. Provide GCLP-level nucleic acid isolation, genomics support and quality control/quality assurance to the laboratory and multidisciplinary programs focused on cancer and infectious disease (including HIV) vaccine and therapy research. (20%) 4. Perform quality control, sequence alignment and preliminary data analysis of next generation sequencing datasets.(15%) 5. Contribute to research so as to merit serving as author or co-author on research publications.(15%) NONESSENTIAL FUNCTIONS 1. Maintain inventory of samples, equipment and reagents and monitor project budgets and expenses. 2. Provide input and make recommendations to the principal investigator regarding significant developments in research projects within the lab and in the public domain. 3. Perform other duties as assigned. CONTACTS: Department: Continuous contact with principal investigator and laboratory staff and postdocs. University: Regular contact with purchasing, human resources, space and facilities planning, environmental health, safety/contact, Research Administration, IRB, and Sponsored Projects Accounting. Frequent contact with collaborators in other university departments and centers. External: Regular contact with vendors and collaborators at other national and international universities, institutions and industry. Occasional contact with granting program directors and project managers. Students: Moderate contact as needed with students. SUPERVISORY RESPONSIBILITY Direct supervisory responsibility for laboratory technicians and research assistants. Direct supervisory responsibilities include the authority to screen, hire, assign, and evaluate laboratory employees or effectively recommend such actions to the principle investigator.
Additional Info:
Diversity Statement In employment, as in education, Case Western Reserve University is committed to Equal Opportunity and Diversity. Women, veterans, members of underrepresented minority groups, and individuals with disabilities are encouraged to apply. Reasonable Accommodations Case Western Reserve University provides reasonable accommodations to applicants with disabilities. Applicants requiring a reasonable accommodation for any part of the application and hiring process should contact the Office of Inclusion, Diversity and Equal Opportunity at 216-368-8877 to request a reasonable accommodation. Determinations as to granting reasonable accommodations for any applicant will be made on a case-by-case basis.[Click Here to Access the Original Job Post]
Working under the supervision of the principal investigator, the Senior Genome Research Assistant will manage projects and design and perform genomic and RNA-Seq experiments with a high degree of independence and assist in analysis. The individual will also communicate directly with the principal investigator and collaborators to facilitate engagement of the principal investigator’s functional genomics laboratory in the completion of projects. ESSENTIAL FUNCTIONS 1. Design, manage, perform and analyze genomic and transcriptomic experiments (e.g. exome, microbiome, RNA-Seq, miRNA-Seq) experiments with a high degree of independence. (25%) 2. Provide supervision, technical guidance and training of technical staff developing novel low-input (including single cell) protocols in next generation sequencing and bioinformatic analysis of the human and macaque genome and transcriptome. (20%) 3. Provide GCLP-level nucleic acid isolation, genomics support and quality control/quality assurance to the laboratory and multidisciplinary programs focused on cancer and infectious disease (including HIV) vaccine and therapy research. (20%) 4. Perform quality control, sequence alignment and preliminary data analysis of next generation sequencing datasets.(15%) 5. Contribute to research so as to merit serving as author or co-author on research publications.(15%) NONESSENTIAL FUNCTIONS 1. Maintain inventory of samples, equipment and reagents and monitor project budgets and expenses. 2. Provide input and make recommendations to the principal investigator regarding significant developments in research projects within the lab and in the public domain. 3. Perform other duties as assigned. CONTACTS: Department: Continuous contact with principal investigator and laboratory staff and postdocs. University: Regular contact with purchasing, human resources, space and facilities planning, environmental health, safety/contact, Research Administration, IRB, and Sponsored Projects Accounting. Frequent contact with collaborators in other university departments and centers. External: Regular contact with vendors and collaborators at other national and international universities, institutions and industry. Occasional contact with granting program directors and project managers. Students: Moderate contact as needed with students. SUPERVISORY RESPONSIBILITY Direct supervisory responsibility for laboratory technicians and research assistants. Direct supervisory responsibilities include the authority to screen, hire, assign, and evaluate laboratory employees or effectively recommend such actions to the principle investigator.
Qualifications:
Experience: 5 years of academic lab experience with 3 years experience in genetics, genomics, next generation sequencing technologies or related research, including familiarity with GCLP. Education/Licensing: Master of Science degree in Molecular Biology, Microbiology, Immunology, Pharmacology, Bioinformatics, Biostatistics or a related discipline. Required skills: 1. Knowledge and understanding of commonly used concepts, practices, and procedures within the field of immunology, functional genomics and next generation sequencing. 2. Ability to perform RNA/DNA isolation and amplification from human and animal samples. 3. Ability to perform Illumina next generation sequencing library, clustering and sequencing with high quality control and assurance. 4.. Ability to operate Illumina next generation sequencing laboratory equipment. 5. Demonstrated ability to perform preliminary sequencing analysis preferred, including alignment and gene expression analysis. 6. Familiarity with BSL-2+ policies and procedures and GCLP. 7. Ability to develop and/or follow standard operating protocols to perform the functions of the job. 8. A demonstrated peer-reviewed publication record is a strong advantage. 9. Professional and effective oral and written communication skills; and good interpersonal skills with the ability to work and communicate with various individuals within and external to the University. 10. Strong organization and independence skills; ability to multi-task, prioritize and meet deadlines.Must demonstrate attention to detail and accuracy, time management skills, and follow-through. 11. Effective academic and management skills; ability to lead, train, work with, and elicit cooperation from team members, staff and collaborators. 12. Ability to work with sensitive information and maintain confidentiality. 13. Effective problem-solving skills; must demonstrate sound judgment and good decision-making. 14. Must demonstrate flexibility and ability to work under pressure; must be able and willing to conform to shifting priorities, demands and timeline. 15. Knowledge of basic accounting practices is preferred. 16. Proficiency in Microsoft Office and database applications preferred. Working conditions: Biosafety Level 2+ lab environment. Hazards include: electrical currents, airborne or contact exposure to bacterial or viral materials, human and animal blood/blood products/biological samples/tissues, toxic or caustic chemicals, and explosive gases.Requeriments :
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Additional Info:
Diversity Statement In employment, as in education, Case Western Reserve University is committed to Equal Opportunity and Diversity. Women, veterans, members of underrepresented minority groups, and individuals with disabilities are encouraged to apply. Reasonable Accommodations Case Western Reserve University provides reasonable accommodations to applicants with disabilities. Applicants requiring a reasonable accommodation for any part of the application and hiring process should contact the Office of Inclusion, Diversity and Equal Opportunity at 216-368-8877 to request a reasonable accommodation. Determinations as to granting reasonable accommodations for any applicant will be made on a case-by-case basis.[Click Here to Access the Original Job Post]