Job ID: 248832470
Job date: 2016-12-14
End Date:
Company : PHS Group Country : Role : Research Scientist
Job date: 2016-12-14
End Date:
Company : PHS Group Country : Role : Research Scientist
Job Description:
Partners HealthCare Personalized Medicine (PPM) is a leader and innovator in helping realize the promise of personalized medicine by accelerating the integration of genetic knowledge into clinical care. PPM is tasked with translating the latest genetic discoveries into routinely orderable genetic tests that are used to improve clinical decision making for patients around the world. The Associate Bioinformatician I will have the opportunity to assist in the development and maintenance of bioinformatics capabilities which support the activities of the Laboratory for Molecular Medicine (a CLIA-certified molecular diagnostic laboratory), PPMs Translational Genomics Core, and the Partners BioBank. A focus will be the support of next-generation sequencing pipelines in the research, translational, and clinical settings. Assigned tasks will depend on the centers priorities and may encompass responsibilities beyond those described here. The successful candidate should have a strong scientific background with prior exposure to genetics and/or genomics, excellent communication and problem-solving skills, and the ability to interact with multidisciplinary staff in a fast-paced environment. Responsibilities: Assist in building different modules of software pipelines for next-generation sequencing applications and array technologies Provide informatics support in development of clinical diagnostic tests Assist in mining/annotation of clinical data. A strong understanding of the principles of genetics is a preferred plus. Assist with current clinical operation pipelines and research operation pipelines Assist with data quality assessment and troubleshooting Assist in the analysis, acquisition, and loading of new data sources Work collaboratively with the group. Create testing, validation, and standard operation procedure documentation. M.Sc. in bioinformatics, computer science or related field. Basic knowledge of algorithms, data structures, and scientific programming. Experience in a Unix/Linux environment, including proficiency in shell scripting, and scripting in a language such as Perl or Python. Some experience with R statistical package or MatLab. Familiarity with common NGS tools (BWA/GATK/Picard Tools, etc). Familiarity using common bioinformatics databases (UCSC, NCBI, etc). Ability to work on multiple projects. This is a dynamic environment where priorities often change. Strong interest in molecular biology and genetics, and a willingness to learn concepts and terminology from these fields as needed.
Additional Info:
As a not-for-profit organization, Partners HealthCare is committed to supporting patient care, research, teaching, and service to the community by leading innovation across our system. Founded by Brigham and Womens Hospital and Massachusetts General Hospital, Partners HealthCare supports a complete continuum of care including community and specialty hospitals, a managed care organization, a physician network, community health centers, home care and other health-related entities. Several of our hospitals are teaching affiliates of Harvard Medical School, and our system is a national leader in biomedical research. Were focused on a people-first culture for our systems patients and our professional family. Thats why we provide our employees with more ways to achieve their potential. Partners HealthCare is committed to aligning our employees personal aspirations with projects that match their capabilities and creating a culture that empowers our managers to become trusted mentors. We support each member of our team to own their personal developmentand we recognize success at every step. Our employees use the Partners HealthCare values to govern decisions, actions and behaviors. These values guide how we get our work done: Patients, Affordability, Accountability & Service Commitment, Decisiveness, Innovation & Thoughtful Risk, and how we treat each other: Diversity & Inclusion, Integrity & Respect, Learning, Continuous Improvement & Personal Growth, Teamwork & Collaboration.[Click Here to Access the Original Job Post]
Partners HealthCare Personalized Medicine (PPM) is a leader and innovator in helping realize the promise of personalized medicine by accelerating the integration of genetic knowledge into clinical care. PPM is tasked with translating the latest genetic discoveries into routinely orderable genetic tests that are used to improve clinical decision making for patients around the world. The Associate Bioinformatician I will have the opportunity to assist in the development and maintenance of bioinformatics capabilities which support the activities of the Laboratory for Molecular Medicine (a CLIA-certified molecular diagnostic laboratory), PPMs Translational Genomics Core, and the Partners BioBank. A focus will be the support of next-generation sequencing pipelines in the research, translational, and clinical settings. Assigned tasks will depend on the centers priorities and may encompass responsibilities beyond those described here. The successful candidate should have a strong scientific background with prior exposure to genetics and/or genomics, excellent communication and problem-solving skills, and the ability to interact with multidisciplinary staff in a fast-paced environment. Responsibilities: Assist in building different modules of software pipelines for next-generation sequencing applications and array technologies Provide informatics support in development of clinical diagnostic tests Assist in mining/annotation of clinical data. A strong understanding of the principles of genetics is a preferred plus. Assist with current clinical operation pipelines and research operation pipelines Assist with data quality assessment and troubleshooting Assist in the analysis, acquisition, and loading of new data sources Work collaboratively with the group. Create testing, validation, and standard operation procedure documentation. M.Sc. in bioinformatics, computer science or related field. Basic knowledge of algorithms, data structures, and scientific programming. Experience in a Unix/Linux environment, including proficiency in shell scripting, and scripting in a language such as Perl or Python. Some experience with R statistical package or MatLab. Familiarity with common NGS tools (BWA/GATK/Picard Tools, etc). Familiarity using common bioinformatics databases (UCSC, NCBI, etc). Ability to work on multiple projects. This is a dynamic environment where priorities often change. Strong interest in molecular biology and genetics, and a willingness to learn concepts and terminology from these fields as needed.
Requeriments :
Skills :
- Bioinformatics
- Genetics
- genomic
- Lunix/Unix
- Next Generation Sequencing
- Programing in Python
- Programming in Matlab
- Programming in PERL
- Programming in R
- Shell scripting
Areas :
Additional Info:
As a not-for-profit organization, Partners HealthCare is committed to supporting patient care, research, teaching, and service to the community by leading innovation across our system. Founded by Brigham and Womens Hospital and Massachusetts General Hospital, Partners HealthCare supports a complete continuum of care including community and specialty hospitals, a managed care organization, a physician network, community health centers, home care and other health-related entities. Several of our hospitals are teaching affiliates of Harvard Medical School, and our system is a national leader in biomedical research. Were focused on a people-first culture for our systems patients and our professional family. Thats why we provide our employees with more ways to achieve their potential. Partners HealthCare is committed to aligning our employees personal aspirations with projects that match their capabilities and creating a culture that empowers our managers to become trusted mentors. We support each member of our team to own their personal developmentand we recognize success at every step. Our employees use the Partners HealthCare values to govern decisions, actions and behaviors. These values guide how we get our work done: Patients, Affordability, Accountability & Service Commitment, Decisiveness, Innovation & Thoughtful Risk, and how we treat each other: Diversity & Inclusion, Integrity & Respect, Learning, Continuous Improvement & Personal Growth, Teamwork & Collaboration.[Click Here to Access the Original Job Post]