Associate Scientist/Scientist, Bioinformatics

Job ID:
Job date: 2018-05-20
End Date: 2018-07-19

Company : Agios Pharmaceuticals 

Country : United States 

Role : Research Scientist 


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Job Description:
Agios Pharmaceuticals is searching for a dynamic Associate Scientist/Scientist to join our growing Informatics team. The Associate Scientist/Scientist will be responsible for Next Generation Sequencing (NGS), single-cell RNAseq, and Microarray data analysis, interpretation, and reporting. This individual will provide Bioinformatics and Genomics support from study design to data analysis and communication of results to various project teams. The candidate is expected to drive projects by translating Bioinformatics analysis results into decisions in experimental steps and program directions.

Key Responsibilities:

  • Responsible for analyzing Agios & public Next Generation Sequencing (NGS) and microarray data, and be a key contributor to the identification of novel cancer targets and patient selection strategies.
  • Participate in different project teams and be the champion and owner of the genomic studies and data interpretations.
  • Performing NGS study design, data processing and analysis, including building analysis pipelines, databases and web portals for result retrieval and visual/graphic display.
  • Conducting scientific presentations for internal/external audiences.
  • Supervise external CRO analysts.
Minimum Requirements:
  • Ph.D. or Master in Computational Biology, Statistics, or a related field, with at least 3 years of hands-on working experience in genetic/genomic data analysis and method development, preferably in Oncology with publications.
  • Strong hands-on programing skills, especially R/Bioconductor, Unix, cluster computing and/or Python, are essential.
  • Strong ability to translate Bioinformatics analysis results into new Biological insights, experimental verification proposals, and program decisions.
  • Self-motivated and able to work independently or in a small team with minimal supervision.
  • Excellent communication and organizational skills.
  • Experienced, and proficient with processing and analysis of next-generation sequencing (NGS) and microarray platforms (expression, methylation, and SNP arrays).
Preferred Qualifications:
  • Experience and/or training in Immunology is preferred.
  • Familiar with TCGA (including Firehose) data structure and result interpretation.
  • Hands-on experience on data visualization tools (R-Shiny, Spotfire, etc).


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Additional Info:
Agios (agios.com) is a biopharmaceutical company committed to applying our scientific leadership in cellular metabolism to transform the lives of patients with cancer and rare genetic diseases. We are growing rapidly with an active research and discovery pipeline across both therapeutic areas. Agios has one approved oncology precision medicine and multiple first-in-class investigational therapies in clinical and/or preclinical development.

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