Job ID: 70519
Job date: 2017-02-01
End Date:
Company : The University of Iowa Country : Role : Research Scientist
Job date: 2017-02-01
End Date:
Company : The University of Iowa Country : Role : Research Scientist
Job Description:
Basic Function and Responsibility: Perform basic and applied research in bioinformatics and image processing, with considerable scope and complexity in which existing theory or methods may be limited or lacking, with responsibility for identifying and selecting the problems to be studied, the approach to them and the results obtained. Specifically, to develop and implement methods of analyzing imaging and large-scale genomic datasets in ocular diseases. The incumbent is expected to work through all phases of experimental design, bioinformatics analysis and interpretation for experiments pertaining to the progression of retinal degenerative disease in both genetic models as well as humans. Characteristic Duties and Responsibilities: 1.Regular daily/weekly use and management of large genomic data sets. 2.Identify and define problems, solutions to which can be approached through a scientific research process.Specific examples include objective measures of gene expression in cells and eyes with different disease phenotypes and establishing methods for OCT segmentation. 3. Gain experience in molecular Ophthalmology. 4. Develop hypotheses to be tested and methodology for evaluating results. 5. Perform experiments and collect and analyze data. 6. Evaluate data to establish relevance to the problem or problems being evaluated. 7. Prepare research results for publication in reports, papers, journals, books and other media. 8. Prepare seminars, discussions and lectures for dissemination of knowledge and results of research. 9. Develop new proposals for research and obtain support for new and/or continuing research activities. 10. Maintain liaison with sponsoring agencies and organizations as well as with other research and educational institutions. 11. Manage all or part of a research project including staff selection, assignment and scheduling, monitoring of project funds, coordination of data generation and analysis and identification, acquisition and use of equipment and facilities. 12. Participate in determining research priorities and planning programs of research. 13. Train investigators and support staff, and conduct continuing education. Maintain effective working relationships with faculty, staff, students and the public. Education Required: A doctorate degree in Bioinformatics or related field. Experience Required: 1. 1-3 years of documentable postdoctoral experience working in bioinformatics or related computational field. 2. 1-3 years of experience working through all phases of experimental design and execution 3. 1-3 years of experience with software development (developing custom software, and adapting existing software) 4. Experience performing quantitative image analysis (OCT segmentation, etc) 5. Experience performing and interpreting gene expression experiments (e.g., microarray and RNA-seq), including design, execution, analysis. 6. Working understanding of human eye anatomy 7. Strong understanding of the genetics of eye disease. Desirable Qualifications: 1. Experience with hardware development and support (robotics, custom hardware). 2. Experience applying Next Generation Sequencing technologies to clinical samples of ocular physiology. 3. Familiarity with multiple programming languages (Perl, Python, C, Java). 4. Familiarity with ImageJ/Fiji. 5. Experience handling human ocular tissue is highly desirable. 6. Experience with the Cufflinks and DESeq packages for RNA-seq analysis is highly desirable. 7. Extensive experience with R. is highly desirable. 8. Experience with single cell transcriptomics is highly desirable.
Additional Info:
Advertising Ends on: Tuesday, February 14th, 2017 Type of Position : Regular: A position which is considered essential for the effective long-term operation of the university. Persons appointed to this position will receive the privileges and benefits associated with regular employment status. Application Type: This job requires basic applicant information, plus a resume. Your resume should not be sent to the contact below. The resume will be attached during the Online Application Process. Cover Letter: A plain text cover letter is required. References: References must be filled out online during the application process, however, only professional references will be allowed. Number of References: 3 The University of Iowa is an equal opportunity/affirmative action employer. All qualified applicants are encouraged to apply and will receive consideration for employment free from discrimination on the basis of race, creed, color, national origin, age, sex, pregnancy, sexual orientation, gender identity, genetic information, religion, associational preference, status as a qualified individual with a disability, or status as a protected veteran. The University also affirms its commitment to providing equal opportunities and equal access to University facilities. Women and Minorities are encouraged to apply for all employment vacancies. For additional information on nondiscrimination policies, contact the Coordinator of Title IX and Section 504, and the ADA in The Office of Equal Opportunity and Diversity, 319/335-0705 (voice) or 319/335-0697 (text), The University of Iowa, 202 Jessup Hall, Iowa City, Iowa, 52242-1316. Persons with disabilities may contact University Human Resources/Faculty and Staff Disability Services, (319) 335-2660 or fsds@uiowa.edu, to inquire or discuss accommodation needs. Prospective employees may review the University Campus Security Policy and the latest annual crime statistics by contacting the Department of Public Safety at 319/335-5022. [Click Here to Access the Original Job Post]
Basic Function and Responsibility: Perform basic and applied research in bioinformatics and image processing, with considerable scope and complexity in which existing theory or methods may be limited or lacking, with responsibility for identifying and selecting the problems to be studied, the approach to them and the results obtained. Specifically, to develop and implement methods of analyzing imaging and large-scale genomic datasets in ocular diseases. The incumbent is expected to work through all phases of experimental design, bioinformatics analysis and interpretation for experiments pertaining to the progression of retinal degenerative disease in both genetic models as well as humans. Characteristic Duties and Responsibilities: 1.Regular daily/weekly use and management of large genomic data sets. 2.Identify and define problems, solutions to which can be approached through a scientific research process.Specific examples include objective measures of gene expression in cells and eyes with different disease phenotypes and establishing methods for OCT segmentation. 3. Gain experience in molecular Ophthalmology. 4. Develop hypotheses to be tested and methodology for evaluating results. 5. Perform experiments and collect and analyze data. 6. Evaluate data to establish relevance to the problem or problems being evaluated. 7. Prepare research results for publication in reports, papers, journals, books and other media. 8. Prepare seminars, discussions and lectures for dissemination of knowledge and results of research. 9. Develop new proposals for research and obtain support for new and/or continuing research activities. 10. Maintain liaison with sponsoring agencies and organizations as well as with other research and educational institutions. 11. Manage all or part of a research project including staff selection, assignment and scheduling, monitoring of project funds, coordination of data generation and analysis and identification, acquisition and use of equipment and facilities. 12. Participate in determining research priorities and planning programs of research. 13. Train investigators and support staff, and conduct continuing education. Maintain effective working relationships with faculty, staff, students and the public. Education Required: A doctorate degree in Bioinformatics or related field. Experience Required: 1. 1-3 years of documentable postdoctoral experience working in bioinformatics or related computational field. 2. 1-3 years of experience working through all phases of experimental design and execution 3. 1-3 years of experience with software development (developing custom software, and adapting existing software) 4. Experience performing quantitative image analysis (OCT segmentation, etc) 5. Experience performing and interpreting gene expression experiments (e.g., microarray and RNA-seq), including design, execution, analysis. 6. Working understanding of human eye anatomy 7. Strong understanding of the genetics of eye disease. Desirable Qualifications: 1. Experience with hardware development and support (robotics, custom hardware). 2. Experience applying Next Generation Sequencing technologies to clinical samples of ocular physiology. 3. Familiarity with multiple programming languages (Perl, Python, C, Java). 4. Familiarity with ImageJ/Fiji. 5. Experience handling human ocular tissue is highly desirable. 6. Experience with the Cufflinks and DESeq packages for RNA-seq analysis is highly desirable. 7. Extensive experience with R. is highly desirable. 8. Experience with single cell transcriptomics is highly desirable.
Requeriments :
Skills :
- Genetics
- Human Biology
- Microarray
- Next Generation Sequencing
- Programing in C
- Programing in Python
- Programming in Java
- Programming in PERL
- Programming in R
- RNA-seq
- Software Design
Areas :
Additional Info:
Advertising Ends on: Tuesday, February 14th, 2017 Type of Position : Regular: A position which is considered essential for the effective long-term operation of the university. Persons appointed to this position will receive the privileges and benefits associated with regular employment status. Application Type: This job requires basic applicant information, plus a resume. Your resume should not be sent to the contact below. The resume will be attached during the Online Application Process. Cover Letter: A plain text cover letter is required. References: References must be filled out online during the application process, however, only professional references will be allowed. Number of References: 3 The University of Iowa is an equal opportunity/affirmative action employer. All qualified applicants are encouraged to apply and will receive consideration for employment free from discrimination on the basis of race, creed, color, national origin, age, sex, pregnancy, sexual orientation, gender identity, genetic information, religion, associational preference, status as a qualified individual with a disability, or status as a protected veteran. The University also affirms its commitment to providing equal opportunities and equal access to University facilities. Women and Minorities are encouraged to apply for all employment vacancies. For additional information on nondiscrimination policies, contact the Coordinator of Title IX and Section 504, and the ADA in The Office of Equal Opportunity and Diversity, 319/335-0705 (voice) or 319/335-0697 (text), The University of Iowa, 202 Jessup Hall, Iowa City, Iowa, 52242-1316. Persons with disabilities may contact University Human Resources/Faculty and Staff Disability Services, (319) 335-2660 or fsds@uiowa.edu, to inquire or discuss accommodation needs. Prospective employees may review the University Campus Security Policy and the latest annual crime statistics by contacting the Department of Public Safety at 319/335-5022. [Click Here to Access the Original Job Post]