Bioinformatician

Job ID: 1313346
Job date: 2017-08-16
End Date:

Company : Battelle 

Country :

Role : Other 


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Job Description:
We are currently seeking a Bioinformatician. This position is located on the Centers for Disease Control and Prevention (CDC) Roybal Campus in Atlanta, Georgia. The position is located in the Influenza Division (ID) of the National Center for Immunization and Respiratory Diseases (NCIRD), CCID, CDC at the Roybal Campus in Atlanta, Georgia.

TOPS is currently seeking a Bioinformatician with experience in computational biology / genomic sequence data analysis. The position is located in the Influenza Division (ID) of the National Center for Immunization and Respiratory Diseases (NCIRD), Office if Infectious Disease (OID), CDC at the Roybal Campus, Atlanta, Georgia. TOPS is working with HHS/CDC in supporting efforts for pandemic influenza preparedness. The CDC ID provides critical standards for pandemic preparedness to the US State Public Health Laboratories and acts as a World Health Organization (WHO) reference laboratory supporting international influenza surveillance and response networks. Rapid genetic and antigenic characterization of circulating viral strains coupled with vaccine development are essential components to increase pandemic readiness and response. TOPS is supporting CDC in research and development efforts to eliminate data gaps in influenza surveillance by increasing the diagnostic and immunization tools available to clinical providers, public health laboratories and domestic and international partners. Monitoring influenza viruses through the application of sequencing technologies and incorporation of laboratory surveillance with classic epidemiology facilitate detection of new epidemic variants and provide complete and accurate information about influenza viruses posing a pandemic threat. The design of protocols and analysis of complex biological data sets from genomics applications (Next Gen Sequencing) are needed to optimize data management and analysis. Our goal is to provide support for enhanced data analysis while working with team members on various pathogen genome sequencing projects. Salary will be determined based on education and experience. The selected applicant will have to obtain and maintain a CDC security clearance.

RESPONSIBILITIES:

  • Use advanced skills and in-depth knowledge of bioinformatics algorithms, tools and resources to accomplish biological sequence retrieval, alignment and clustering techniques, expression profiling and protein related analysis
  • Develop pipelines using custom and existing open source bioinformatics tools to automate data management and analysis of biological sequence data
  • Perform data management and analysis of viral pathogen derived NGS data including assembly, mapping, annotation, and whole-genome comparison as well as evaluate quality metrics of generated data from multiple NGS platforms such as MiSeq, NextSeq, HiSeq, MinIon and PacBio RS
  • Use and develop bioinformatics pipelines to perform metagenomics analyses of next generation sequencing data (NGS) obtained from existing and newly emerging NGS platforms
  • Perform genetic transmission analysis using algorithms that utilize meta-data overlays to expand context of derived transmission profiles
  • Provide extensible script-based configuration tools to enable automation of data management/analysis workflows within systems
  • Provide support in Linux/unix computer system;
  • Design, write and utilize scripts in Python, PERL, BioPERL, java, python, ruby or groovy for automation of data analysis and visualization
  • Contribute to the development of procedures and standards for database development
  • Contribute to the formation of project proposals and progress reports for the Division information management system; Contribute to the development of technical documents, standard operating procedures and manuscripts
  • Maintain detailed records that meet good documentation practice standards
  • Train/support junior staff as needed
  • Maintain compliance with all CDC safety and IT security requirements
  • Some travel may be required.
THE FOLLOWING REQUIREMENTS MUST BE MET TO BE CONSIDERED FOR THIS POSITION:
  • BS with 5-8 years’ experience in a life sciences discipline with demonstrated background/experience in Bioinformatics or Computational Biology OR BS degree with 5-8 years’ experience in a computer science discipline with demonstrated background/experience providing service for life science projects
  • Must be able to obtain and maintain a CDC Security Clearance
THE FOLLOWING IS DESIRED, BUT NOT REQUIRED TO BE CONSIDERED FOR THIS POSITION:
  • Master’s or Ph.D. degree in a life science discipline with a strong emphasis on Bioinformatics/Computational Biology or Bioinformatics/Computational Biology with a focus on the use of Next Generation Sequencing technologies
  • Proficiency performing human genetics analysis
  • Proficiency using Cloudera Hadoop systems, particularly data migration and advanced querying
  • Proficiency using Github for maintenance of software project components


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Additional Info:
Battelle is guided by a founding mission. We invest our knowledge, talents and resources, helping our customers achieve their most important goals. We apply scientific rigor and creativity, succeeding where others may fail and we invest in our communities, making the world better for generations to come. All of us share a common purpose: to solve the greatest challenges of today and tomorrow.

Battelle’s Technical On-site Professional Services (TOPS) is a part of the Contract Research business within Battelle providing laboratory support to the Centers for Disease Control and Prevention (CDC).

TOPS is working with HHS/CDC in supporting efforts for pandemic influenza preparedness. The CDC ID provides critical standards for pandemic preparedness to the US State Public Health Laboratories and acts as a World Health Organization (WHO) reference laboratory supporting international influenza surveillance and response networks. Rapid genetic and antigenic characterization of circulating viral strains coupled with vaccine development are essential components to increase pandemic readiness and response.

Our 22,000 employees work at the forefront of scientific innovation to tackle critical challenges in security, human health, manufacturing, energy and environmental management. Battelle’s work is grounded in the belief that science, technology and a passion for excellence can make industries more competitive and the world a better place.

BENEFITS

Battelle is an Affirmative Action/Equal Opportunity Employer and supports diversity in the workplace. Applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, age, disability, veteran status, marital status, or sexual orientation. For more information about our other openings, please visit www.battelle.org/careers

For more information about our other openings, please visit www.battelle.org/careers

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