Job ID: 617565
Job date: 2017-06-19
End Date:
Company : Heptares Therapeutics Country : Role : Postdoc
Job date: 2017-06-19
End Date:
Company : Heptares Therapeutics Country : Role : Postdoc
Job Description:
We are currently seeking an experienced Bioinformatician to work with scientists internally and externally across a range of disciplines to advance both our platform technology and our pipeline of new medicines. Our preferred candidate would have the following background: · Educated to PhD level in Biochemistry or a related Biomedical science, with experience in applying Bioinformatics approaches to Biomedical questions · Expertise in R programming and Python scripting · A solid understanding of protein families, their physiological functions and their regulation by endogenous and exogenous ligands · Broad knowledge of 3D structures of proteins and ligands · Experience with the development and application of informatics approaches to analyse databases (including protein sequences and structures) · Familiarity with integrated sequence/structure/small molecule approaches and databases (e.g. ChEMBL) · Experience of working in a drug discovery environment would be an advantage The successful candidate will work independently but in association with other Heptares functions to: · Mine databases, publications and other sources of information to help generate disease/protein associations and identify suitable targets for drug discovery · Assist with the assessment of opportunities for new projects involving novel targets and/or novel drug molecules · Work with selected academic partners to use informatics data to progress target validation and drug discovery projects · Examine the effects of sequence variation on the structure and function of proteins · Analyse the rapidly growing body of data on structure-function relationships within GPCRs · Maintain and present summaries of informatics analyses in a form suitable for broader use · Keep up to date with Bioinformatics methodologies as applied to drug discovery This is an exceptional opportunity to participate in pioneering science with an industry-leading Drug Discovery company.
Additional Info:
Heptares Therapeutics is clinical stage company using innovative techniques in protein engineering and structure based drug design directed at G protein-coupled receptors (GPCRs). Heptares has built an exciting pipeline of new medicines across disease areas including Alzheimer's disease, migraine and cancer. Our ability to address highly validated, yet historically undruggable, GPCRs has also attracted multiple partners including Allergan, AstraZeneca, Daiichi Sankyo, Kymab, Morphosys, Pfizer and Teva. We offer a competitive salary and benefits package commensurate with qualifications and experience. Applicants must be able to demonstrate proof of the right to work in the United Kingdom. Heptares Therapeutics is an equal opportunities employer. Further information can be found on our website (www.heptares.com). Applications should include a covering letter with curriculum vitae including the names and contact details for two referees. Please send your application in pdf format, to hr@heptares.com quoting reference number 2017/2BMS. The closing date for applications is 14th July 2017. Strictly no agencies.[Click Here to Access the Original Job Post]
We are currently seeking an experienced Bioinformatician to work with scientists internally and externally across a range of disciplines to advance both our platform technology and our pipeline of new medicines. Our preferred candidate would have the following background: · Educated to PhD level in Biochemistry or a related Biomedical science, with experience in applying Bioinformatics approaches to Biomedical questions · Expertise in R programming and Python scripting · A solid understanding of protein families, their physiological functions and their regulation by endogenous and exogenous ligands · Broad knowledge of 3D structures of proteins and ligands · Experience with the development and application of informatics approaches to analyse databases (including protein sequences and structures) · Familiarity with integrated sequence/structure/small molecule approaches and databases (e.g. ChEMBL) · Experience of working in a drug discovery environment would be an advantage The successful candidate will work independently but in association with other Heptares functions to: · Mine databases, publications and other sources of information to help generate disease/protein associations and identify suitable targets for drug discovery · Assist with the assessment of opportunities for new projects involving novel targets and/or novel drug molecules · Work with selected academic partners to use informatics data to progress target validation and drug discovery projects · Examine the effects of sequence variation on the structure and function of proteins · Analyse the rapidly growing body of data on structure-function relationships within GPCRs · Maintain and present summaries of informatics analyses in a form suitable for broader use · Keep up to date with Bioinformatics methodologies as applied to drug discovery This is an exceptional opportunity to participate in pioneering science with an industry-leading Drug Discovery company.
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Additional Info:
Heptares Therapeutics is clinical stage company using innovative techniques in protein engineering and structure based drug design directed at G protein-coupled receptors (GPCRs). Heptares has built an exciting pipeline of new medicines across disease areas including Alzheimer's disease, migraine and cancer. Our ability to address highly validated, yet historically undruggable, GPCRs has also attracted multiple partners including Allergan, AstraZeneca, Daiichi Sankyo, Kymab, Morphosys, Pfizer and Teva. We offer a competitive salary and benefits package commensurate with qualifications and experience. Applicants must be able to demonstrate proof of the right to work in the United Kingdom. Heptares Therapeutics is an equal opportunities employer. Further information can be found on our website (www.heptares.com). Applications should include a covering letter with curriculum vitae including the names and contact details for two referees. Please send your application in pdf format, to hr@heptares.com quoting reference number 2017/2BMS. The closing date for applications is 14th July 2017. Strictly no agencies.[Click Here to Access the Original Job Post]