Bioinformaticist – Renal – 38320

Job ID: 38320
Job date: 2017-10-22
End Date:

Company : Washington University in St. Louis 

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Job Description:
We are seeking a highly motivated individual who to join our single cell sequencing team. The primary job responsibility will be the bioinformatics analysis of high dimensional scRNA-seq datasets.

Training will be provided as needed, however programming experience (R, Python) and RNA-sequencing analysis experience is required. The successful applicant will also have substantial molecular biology experience. This position offers superb opportunities for continued scientific learning and career development including primary and coauthorship, and is full-time. The successful applicant will also learn all aspects of the single cell RNA-Seq workflow, including tissue dissociation, microfluidic encapsulation, library generation, sequencing and bioinformatic analysis of sequencing data. This position is well suited to PhD scientists who do not wish to pursue an independent career but want to be a part of a dynamic team ion a very fast moving field.

The successful applicant will hold the title of Bioinformaticist. The Humphreys Lab is a collaborative, highly productive and fun scientific work environment.

PRIMARY DUTIES AND RESPONSIBILITIES:

  1. Designs, develops, and implements:
    • Algorithms and computer software for analyzing high-throughput, massively parallel genomic data sets
    • Relational databases to store, disseminate and analyze data, including verification of data submitted and recommendations for analyses
    • Web interfaces and queries to access relational databases; maintains web server
    • Independent research projects, including design of research protocols and development of procedures for the collection, verification, and management of data
  2. Performs complex systems analysis of data and writes interpretative reports
  3. Evaluates commercial and academic bioinformatics software
  4. Trains other researchers on the everyday use of analysis software and research databases
  5. Assists with grant preparation and reporting of methods, data, and results
  6. Solves practical problems relating to difficulties with equipment or test subjects; suggests technical or procedural improvements in testing methods
Required Qualifications: Bachelor’s degree in science or related field plus 4 years of experience required.

Preferred Qualifications:

  • Master’s degree or Ph.D. in computer science or related field highly preferred
  • Strong expertise in molecular biology
  • Prior software programming experience
  • Strong organization, record keeping and computer skills
  • Excellent communication, interpersonal and time management skills
  • Ability to handle multiple tasks and/or requests with minimal supervision
  • Detail oriented with ability to learn tasks independently within scope of responsibility
Salary Range:The hiring range for this position is $52,769 - $71,240 annually.


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Additional Info:
Job Type/Schedule: This position is full-time and works approximately 40 hours per week.

Department Name/Job Location: This position is in the Department of Internal Medicine, Renal Division. This position is for the Medical School Campus.

The field of single cell transcriptomincs by RNA-Seq at high-throughput scale is revolutionizing biological investigation. Microfluidic droplet technologies allow co-encapsulation of a cell, barcoded DNA oligonucleotides and cell lysis buffer within a tiny droplet of about 2 nanoliters. These transformative approaches allow for parallel processing of thousands of cells with great efficiency and precision and they are already having far-reaching impacts across biology and medicine. We are applying two separate droplet microfluidics-based approaches, Drop-Seq and InDrops, for single cell RNA-sequencing of human and mouse kidney and human pluripotent stem cell-derived kidney organoids.

Department Summary

The Humphreys lab consists of 8 post-doctoral fellows, three research assistants. An overview of the Humphreys Lab research can be found at: http://humphreyslab.com/.

Benefits

This position is eligible for full-time benefits. Please visit our website at http://hr.wustl.edu to view a summary of benefits.

Applicant Special Instructions

Please submit a letter explaining your interest, a CV/resume, and contact information for three references with your application.

Works in laboratory environment with potential exposure to biological, chemical and radioactive hazards.

Must be physically able to wear protective equipment.

Must be able to provide standard care to research animals.

EOE Statement

Washington University is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, age, sex, sexual orientation, gender identity or expression, national origin, genetic information, disability, or protected veteran status.

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