Job Description:
This position will provide general bioinformatics support for RGC teams, with a focus on the interpretation and understanding of the functional impact of sequence variants. The ideal analyst candidate would have a strong customer focus and experience with bioinformatics tools used to interpret and analyze NGS variants. Requirements: This position requires a Master’s degree in computational biology or bioinformatics and/or 2+ years of experience in NGS data analysis. Additional requirements include: • A strong communicator with a customer-focused attitude • Previous experience with NGS variant annotation and analysis tools • Experience using standard bioinformatics NGS variant annotation tools (e.g. SNPeff, AnnoVAR, etc.) • Experience in working with various annotation resources (e.g., dbNSFP, HGMD, GenomeTrax) • Experience writing and applying analysis scripts (Python, Perl, etc.) in a Linux/UNIX environment • Familiarity with R • Demonstrated ability to apply and troubleshoot computational tools and workflows • Experience in a cloud computing environments is a plus Roles & Responsibilities: • Support the all RGC teams’ bioinformatics and analysis needs • Apply RGC analysis & annotation tools to provide bioinformatic variant assessments and annotations • Update resources and annotations routinely to be in sync with broader update cycle of RGC tools • Working from customer requirements, deliver timely and accurate analysis results • Support RNAseq analysis interpretation and annotation work • Install and execute published/commercial software relevant to variant/gene annotation and interpretation • Communicate and collaborate closely with customers and RGC team members This is an opportunity to join our select team that is already leading the way in the Pharmaceutical/Biotech industry. Apply today and learn more about Regeneron’s unwavering commitment to combining good science & good business.
Additional Info:
The Regeneron Genetics Center (RGC) is a wholly-owned subsidiary of the Company, whose goals are to apply large scale human genetics to identify new drug targets and to guide the development of therapeutics programs and precision medicine. Building upon Regeneron's strengths in mouse genetics and genetics-driven drug discovery and development, the RGC specializes in ultra-high-throughput exome sequencing, large scale informatics and data analysis encompassing genomics and electronic health records, and translating genetic discoveries into new biology and drug discovery opportunities. The RGC leverages multiple approaches including large population based studies, Mendelian genetics and family based studies, founder population genetics, and large-scale disease focused projects and has developed a network of over 50 collaborations with research organizations around the world. Including some of the largest sequencing studies in the world, such as the DiscovEHR study in collaboration with Geisinger Health System, and an initiative to sequence 500,000 participants with the UK Biobank, the RGC has built one of the largest human genetics databases, including sequence data from over several hundred thousand participants and rapidly growing. Our interests encompass a breadth of different areas across all therapeutic areas and the RGC is highly integrated into all facets of research and development at Regeneron. Program goals include target discovery, indication discovery, and patient-disease stratification. Objectives include advancing basic science around the world through public sharing of discoveries, providing clinically-valuable insights to physicians and providers of collaborating health-care systems, improving patient outcomes, and identifying novel targets for drug development. To all agencies: Please, no phone calls or emails to any employee of Regeneron about this opening. All resumes submitted by search firms/employment agencies to any employee at Regeneron via-email, the internet or in any form and/or method will be deemed the sole property of Regeneron, unless such search firms/employment agencies were engaged by Regeneron for this position and a valid agreement with Regeneron is in place. In the event a candidate who was submitted outside of the Regeneron agency engagement process is hired, no fee or payment of any kind will be paid. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law. Employment Type: Regular Employee[Click Here to Access the Original Job Post]
This position will provide general bioinformatics support for RGC teams, with a focus on the interpretation and understanding of the functional impact of sequence variants. The ideal analyst candidate would have a strong customer focus and experience with bioinformatics tools used to interpret and analyze NGS variants. Requirements: This position requires a Master’s degree in computational biology or bioinformatics and/or 2+ years of experience in NGS data analysis. Additional requirements include: • A strong communicator with a customer-focused attitude • Previous experience with NGS variant annotation and analysis tools • Experience using standard bioinformatics NGS variant annotation tools (e.g. SNPeff, AnnoVAR, etc.) • Experience in working with various annotation resources (e.g., dbNSFP, HGMD, GenomeTrax) • Experience writing and applying analysis scripts (Python, Perl, etc.) in a Linux/UNIX environment • Familiarity with R • Demonstrated ability to apply and troubleshoot computational tools and workflows • Experience in a cloud computing environments is a plus Roles & Responsibilities: • Support the all RGC teams’ bioinformatics and analysis needs • Apply RGC analysis & annotation tools to provide bioinformatic variant assessments and annotations • Update resources and annotations routinely to be in sync with broader update cycle of RGC tools • Working from customer requirements, deliver timely and accurate analysis results • Support RNAseq analysis interpretation and annotation work • Install and execute published/commercial software relevant to variant/gene annotation and interpretation • Communicate and collaborate closely with customers and RGC team members This is an opportunity to join our select team that is already leading the way in the Pharmaceutical/Biotech industry. Apply today and learn more about Regeneron’s unwavering commitment to combining good science & good business.
Requeriments :
Skills :
- Cloud Computing
- Lunix/Unix
- Next Generation Sequencing
- Programing in Python
- Programming in PERL
- Programming in R
Areas :
Additional Info:
The Regeneron Genetics Center (RGC) is a wholly-owned subsidiary of the Company, whose goals are to apply large scale human genetics to identify new drug targets and to guide the development of therapeutics programs and precision medicine. Building upon Regeneron's strengths in mouse genetics and genetics-driven drug discovery and development, the RGC specializes in ultra-high-throughput exome sequencing, large scale informatics and data analysis encompassing genomics and electronic health records, and translating genetic discoveries into new biology and drug discovery opportunities. The RGC leverages multiple approaches including large population based studies, Mendelian genetics and family based studies, founder population genetics, and large-scale disease focused projects and has developed a network of over 50 collaborations with research organizations around the world. Including some of the largest sequencing studies in the world, such as the DiscovEHR study in collaboration with Geisinger Health System, and an initiative to sequence 500,000 participants with the UK Biobank, the RGC has built one of the largest human genetics databases, including sequence data from over several hundred thousand participants and rapidly growing. Our interests encompass a breadth of different areas across all therapeutic areas and the RGC is highly integrated into all facets of research and development at Regeneron. Program goals include target discovery, indication discovery, and patient-disease stratification. Objectives include advancing basic science around the world through public sharing of discoveries, providing clinically-valuable insights to physicians and providers of collaborating health-care systems, improving patient outcomes, and identifying novel targets for drug development. To all agencies: Please, no phone calls or emails to any employee of Regeneron about this opening. All resumes submitted by search firms/employment agencies to any employee at Regeneron via-email, the internet or in any form and/or method will be deemed the sole property of Regeneron, unless such search firms/employment agencies were engaged by Regeneron for this position and a valid agreement with Regeneron is in place. In the event a candidate who was submitted outside of the Regeneron agency engagement process is hired, no fee or payment of any kind will be paid. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law. Employment Type: Regular Employee[Click Here to Access the Original Job Post]