Job ID: 22019
Job date: 2017-05-06
End Date:
Company : Medical College of Wisconsin Country : Role : Technician
Job date: 2017-05-06
End Date:
Company : Medical College of Wisconsin Country : Role : Technician
Job Description:
Under general supervision, works as part of a multidisciplinary team providing service and support to the Biomedical Research and Individual Medicine units of the Human and Molecular Genetics Center. Determines and performs appropriate bioinformatic anlaysis of data generated through high complexity techniques such as next generation sequencing, electronic medical record, and other biomedical research and clinical data. Works with multidisciplinary development teams to develop new methodology and tools for analysis, and/or to define improvements for existing systems and tools. Primary Functions: 1. Understands Next Generation Sequencing (NGS) principles and results in the context of molecular diagnostics to analyze NGS data. Independently provides troubleshooting feedback to wet lab for NGS data and creates clinical NGS reports. 2. Develops, implements, and refines bioinformatic workflows and analytical tools for analyzing and visualizing NGS data. 3. Adapts standard bioinformatics tools, visualization packages, and NGS database/annotation resources for research projects to independently and accurately perform routine analysis. 4. Performs CLIA-level validation of new procedures, protocols, software, and translational medicine projects under the direction of Bioinformatics Lead. 5. Oversees all LIMS workflows and validation procedures for the CLIA laboratory and multiple research projects. Interfaces LIMS with existing and new platforms. 6. Works with DBA and system administrator to implement and optimize databases and data storage methods. 7. Contributes to publications by providing figures, tables, and text to accurately illustrate analytical methods & results. 8. Operates and troubleshoots key analytic tools; notifies Supervisor when complex problems occur. 9. Operates, calibrates, maintains, and troubleshoots equipment; notifies Lead Clinical Analyst when complex problems occur. 10. Performs other duties as needed or indicated by Supervisor. Position Requirements: Specifications Minimum Education: Bachelor's degree, Master’s degree Preferred Prior Experience: 2 years Preferred Field of Study: Biomedical or quantitative science, Information Systems, Bioinformatics, Biomedical Informatics, Computer Science, or comparable field Knowledge, Skills, and Abilities: This position requires cross-disciplinary and strong analytical skills as well as broad experience using computational methods, databases, software, and hardware. Working (professional / academic) experience with bioinformatics tools and algorithms on large-scale data. Familiarity with programming languages (Python, Perl or similar), Database, mathematical, computational and/or statistical software, (R, GATK, or similar), Linux (or similar). Experience with Linux-based HPC clusters (hard or cloud). Organized, detail-oriented, and capable of collecting and analyzing large amounts of data. A basic background in Human Genetics is essential along with understanding of the biology, molecular mechanisms and functional studies of disease genes. Ability to critically read, understand, and interpret data from scientific publications on a daily basis.
Additional Info:
Location: HRC Department: Human Molecular Genetics Center Division: HMGC Bioinformatics Reports to (title): Most Senior Bioinformatics Analyst II Direct Reports (title): Collaborates with (title): Bioinformatics Analyst I, Clinical DB and Applications Specialists, other HMGC quantitative, lab, and analytic positions Workweek: Full-time role with expectations for coverage during core business hours and flexibility required as necessary to accommodate business needs. About MCW : The Medical College of Wisconsin (MCW) is one of the largest healthcare employers in Wisconsin. We are a distinguished leader and innovator in the education and development of the next generation of physicians, scientists, pharmacists and health professionals; we discover and translate new knowledge in the biomedical and health sciences; we provide cutting-edge, collaborative patient care of the highest quality; and we improve the health of the communities we serve. We are an Equal Opportunity Employer and do not discriminate against any employee or applicant for employment because of race, color, sex, age, national origin, religion, sexual orientation, gender identity, status as a veteran, and basis of disability or any other federal, state or local protected class. [Click Here to Access the Original Job Post]
Under general supervision, works as part of a multidisciplinary team providing service and support to the Biomedical Research and Individual Medicine units of the Human and Molecular Genetics Center. Determines and performs appropriate bioinformatic anlaysis of data generated through high complexity techniques such as next generation sequencing, electronic medical record, and other biomedical research and clinical data. Works with multidisciplinary development teams to develop new methodology and tools for analysis, and/or to define improvements for existing systems and tools. Primary Functions: 1. Understands Next Generation Sequencing (NGS) principles and results in the context of molecular diagnostics to analyze NGS data. Independently provides troubleshooting feedback to wet lab for NGS data and creates clinical NGS reports. 2. Develops, implements, and refines bioinformatic workflows and analytical tools for analyzing and visualizing NGS data. 3. Adapts standard bioinformatics tools, visualization packages, and NGS database/annotation resources for research projects to independently and accurately perform routine analysis. 4. Performs CLIA-level validation of new procedures, protocols, software, and translational medicine projects under the direction of Bioinformatics Lead. 5. Oversees all LIMS workflows and validation procedures for the CLIA laboratory and multiple research projects. Interfaces LIMS with existing and new platforms. 6. Works with DBA and system administrator to implement and optimize databases and data storage methods. 7. Contributes to publications by providing figures, tables, and text to accurately illustrate analytical methods & results. 8. Operates and troubleshoots key analytic tools; notifies Supervisor when complex problems occur. 9. Operates, calibrates, maintains, and troubleshoots equipment; notifies Lead Clinical Analyst when complex problems occur. 10. Performs other duties as needed or indicated by Supervisor. Position Requirements: Specifications Minimum Education: Bachelor's degree, Master’s degree Preferred Prior Experience: 2 years Preferred Field of Study: Biomedical or quantitative science, Information Systems, Bioinformatics, Biomedical Informatics, Computer Science, or comparable field Knowledge, Skills, and Abilities: This position requires cross-disciplinary and strong analytical skills as well as broad experience using computational methods, databases, software, and hardware. Working (professional / academic) experience with bioinformatics tools and algorithms on large-scale data. Familiarity with programming languages (Python, Perl or similar), Database, mathematical, computational and/or statistical software, (R, GATK, or similar), Linux (or similar). Experience with Linux-based HPC clusters (hard or cloud). Organized, detail-oriented, and capable of collecting and analyzing large amounts of data. A basic background in Human Genetics is essential along with understanding of the biology, molecular mechanisms and functional studies of disease genes. Ability to critically read, understand, and interpret data from scientific publications on a daily basis.
Requeriments :
Skills :
- Bioinformatics Databases
- Biology
- Genetics
- HPC
- LIMS
- Lunix/Unix
- Mathematics
- Next Generation Sequencing
- Programing in Python
- Programing Skills
- Programming in PERL
- Programming in R
Areas :
Additional Info:
Location: HRC Department: Human Molecular Genetics Center Division: HMGC Bioinformatics Reports to (title): Most Senior Bioinformatics Analyst II Direct Reports (title): Collaborates with (title): Bioinformatics Analyst I, Clinical DB and Applications Specialists, other HMGC quantitative, lab, and analytic positions Workweek: Full-time role with expectations for coverage during core business hours and flexibility required as necessary to accommodate business needs. About MCW : The Medical College of Wisconsin (MCW) is one of the largest healthcare employers in Wisconsin. We are a distinguished leader and innovator in the education and development of the next generation of physicians, scientists, pharmacists and health professionals; we discover and translate new knowledge in the biomedical and health sciences; we provide cutting-edge, collaborative patient care of the highest quality; and we improve the health of the communities we serve. We are an Equal Opportunity Employer and do not discriminate against any employee or applicant for employment because of race, color, sex, age, national origin, religion, sexual orientation, gender identity, status as a veteran, and basis of disability or any other federal, state or local protected class. [Click Here to Access the Original Job Post]