Job Description:
KEY ROLES/RESPONSIBILITIES
Additional Info:
The Molecular Characterization Laboratory (MoCha) is part of Leidos Biomedical Research’s Clinical Research Directorate (CRD) at the Frederick National Laboratory for Cancer Research. The MoCha Laboratory is responsible for providing high-level research in support of the NCI-Cancer Diagnostics Program (CDP) within the Division of Cancer Treatment and Diagnosis (DCTD). MoCha is charged with the development and application of genomic assays for use in medical research and diagnostics for DCTD-sponsored national extramural clinical trials. Leidos Overview: Leidos is a global science and technology solutions leader working to solve the world’s toughest challenges in the defense, intelligence, homeland security, civil, and health markets. The company’s 33,000 employees support vital missions for government and commercial customers. Headquartered in Reston, Virginia, Leidos reported pro forma annual revenues of approximately $10 billion for the fiscal year ended January 1, 2016 after giving effect to the recently completed combination of Leidos with Lockheed Martin's Information Systems & Global Solutions business (IS&GS). For more information, visit www.Leidos.com. The company’s diverse employees support vital missions for government and commercial customers. Qualified women, minorities, individuals with disabilities and protected veterans are encouraged to apply. Leidos will consider qualified applicants with criminal histories for employment in accordance with relevant Laws. Leidos is an Equal Opportunity Employ [Click Here to Access the Original Job Post]
KEY ROLES/RESPONSIBILITIES
- Provide substantial bioinformatics support for the MoCha clinical laboratory, including the analysis and interpretation of high throughput genomic data
- Provide expertise in the biological interpretation of results, including mutation impact assessment, expression analysis,statistics support and prioritization of identified loci/genes lists, classification model building and determining correlation with clinical data derived from patients
- Interact with investigators throughout the entire experimental process from study design to result interpretation including manuscript preparation
- Provide support to lab staff in the application of basic data analysis and study design
- Provide bioinformatics knowledge as a shared team resource
- Maintain and track complex data for multiple projects
- Work with lab managers to update genetic information in databases
- Work closely with clinical lab staff to provide computation resources and to support data analysis and storage
- Coordinate and integrate software applications and databases within the larger group including the Bethesda, Frederick, and Shady Grove NCI campuses
- This position is located in Frederick, MD
Qualifications:
BASIC QUALIFICATIONS: To be considered for this position, you must minimally meet the knowledge, skills, and abilities listed below:- Possession of a Bachelor's degree (Master’s Degree preferred) in biomedical science/bioinformatics/math/statistics/computer related field from an accredited college or university according to the Council for Higher Education Accreditation (CHEA) (Additional qualifying experience may be substituted for the required education).
- Foreign degrees must be evaluated for U.S. equivalency
- A minimum of five (5) years related computational experience in a biological/medical research laboratory environment with a strong background in bioinformatics application development
- Experience in next generation sequence analysis (NGS) including quality metrics, mapping, variant calling and biological interpretation, and experience with analysis of large genomic data sets including integration with data available from public or private sources
- Hands-on experience in data processing and analyzing sequencing, expression and other array data including quality and biological assessment
- Proficiency in Unix (Linux) system, scripting and programming languages such as Shell, R, Python, JavaScript, Perl, Java, SQL and bioinformatics tools and database management
- Experience in statistical analysis of complex biological data
- Experience and demonstrated success in a team-oriented environment
- Information tracking experience for data with complex structures
- Must be able to obtain and maintain a security clearance
- Peer reviewed publications demonstrating knowledge of the biology of cancer
- Experience with Ion Torrent systems, including the Ion Reporter system
- Experience in data integration, database construction, application development and visualization
- Experience in porting applications to a web environment and working with workflow tools and applications
Requeriments :
Skills :
- Bioinformatics
- Bioinformatics Databases
- Biology
- Cancer biology
- genomic
- JavaScript
- Lunix/Unix
- Next Generation Sequencing
- Programing in Python
- Programing Skills
- Programming in Java
- Programming in PERL
- Programming in R
- Shell scripting
- SQL
- Statistics
Areas :
Additional Info:
The Molecular Characterization Laboratory (MoCha) is part of Leidos Biomedical Research’s Clinical Research Directorate (CRD) at the Frederick National Laboratory for Cancer Research. The MoCha Laboratory is responsible for providing high-level research in support of the NCI-Cancer Diagnostics Program (CDP) within the Division of Cancer Treatment and Diagnosis (DCTD). MoCha is charged with the development and application of genomic assays for use in medical research and diagnostics for DCTD-sponsored national extramural clinical trials. Leidos Overview: Leidos is a global science and technology solutions leader working to solve the world’s toughest challenges in the defense, intelligence, homeland security, civil, and health markets. The company’s 33,000 employees support vital missions for government and commercial customers. Headquartered in Reston, Virginia, Leidos reported pro forma annual revenues of approximately $10 billion for the fiscal year ended January 1, 2016 after giving effect to the recently completed combination of Leidos with Lockheed Martin's Information Systems & Global Solutions business (IS&GS). For more information, visit www.Leidos.com. The company’s diverse employees support vital missions for government and commercial customers. Qualified women, minorities, individuals with disabilities and protected veterans are encouraged to apply. Leidos will consider qualified applicants with criminal histories for employment in accordance with relevant Laws. Leidos is an Equal Opportunity Employ [Click Here to Access the Original Job Post]