Bioinformatics Scientist

Job Description:
Are you motivated to participate in a dynamic, multi-tasking environment? Do you want to become part of a company that invests in its employees? Are you seeking a position where you can use your skills while continuing to be challenged and learn? Then we encourage you to dive deeper into this opportunity.

NeoGenomics is looking for a Bioinformatics Research Scientist within our Molecular Laboratory who will report directly to the technical director of the Molecular Laboratory. This position is primarily a genomics analyst based position and will assist R&D in developing advanced NGS pipelines for targeted cancer therapy to prepare CAP, CLIA, NCI-Match, NYS, FDA applications/submissions. The person will also be responsible for developing bioinformatic pipelines and custom analysis for validation/troubleshooting of assays required for preliminary for prospective clinical trials as well as maintaining local shared NGS cluster resources.

As a Bioinformatics Research Scientist you will support the dynamic goals of the fast paced genomics environment in industry. Responsibilities will include, but not be limited to the following:

• Lead the Development, analytical testing and validation of new bioinformatic pipelines to improve Neogenomics clinical diagnostic NGS platform with an emphasis on rigorously validation and robust procedures. Working closely with an interdisciplinary team of clinical laboratory scientists, pathologists, R&D scientists, marketing, and sales teams to bring new methods to the operational level.
• Assist with drafting and completing government applications (NIH, FDA, NYS, CLIA, CAP) and manuscripts for publication; lead data analysis and interpretation of study results throughout application/publication process from draft through submission and acceptance.
• Enhance existing bioinformatics methods, improving their assay capabilities as well as their technical robustness.
• Monitor and evaluate analytical aspects of new and emerging technologies.
• Process, analyze, and interpret high volumes of data for the development and validation of methods.
• Present scientific and technical data to colleagues in a clear and cohesive manner.
• Work independently and prepare timetables, deliverables, and project schedules.

Experience & Required Qualifications:

Education: Masters 2-4 years or Ph.D. Molecular Biology, Bioinformatics, Genomic Sciences, Genetics, Cancer Biology or 1-2 yrs w/direct NGS experience

Required Experience:

• In this role, you should have working knowledge of molecular biology with strong scientific understanding of genomics and show a strong capacity for independent thinking.
• Required knowledge of common genomic terminology (exome, targeted RNA/DNA panels, gene structure), databases (UCSC/EBI/NIH), genome versions, and tools used in genomics (e.g. dbSNP, COSMIC, ClinVar, UCSC genome browser, Galaxy, IGV)
• Required working analysis experience of large genomic datasets (RNAseq profiling, somatic variant analysis, CNV analysis, bioinformatics QC of libraries, TCGA), and use of common bioinformatics tools (TopHat, BWA, GATK, SAMtools, pysam, Picard Tools, Bowtie, edgeR, DESeq, BWA etc…).
• Required Linux/Unix terminal/command line-only expertise; GUI/MS-based experience will not be considered. You should have first-hand experience maintaining common use parallel computing environments/clusters, like SGE/Torque clusters.
• Required knowledge of R command line; and R figures and plots.
• Required expert efficiency in BASH and scripting languages (e.g. Python) languages
• A high level of professional maturity, including an ability to consistently meet tight deadlines under pressure and command attention and respect in a client-facing setting.
• Capability of highly-independent work as well as being a team player and role model.
• High energy level, a driving sense of urgency and a seasoned “make it happen/can do” orientation

Preferred:

• Experience in cancer or genetics research, including a working understanding of computational approaches for cancer/genetic genome analysis, is helpful.
• Knowledge of Bioinformatic approaches to RNA normalization, Variant annotation, CNV tools, UMI tools, translocation and fusions identification, and MSI.
• Established scientific/technical writing and presentation skills; publication/manuscript/CAP/CLIA/NYS validation, NIH grant experience greatly preferred.
• Fluency in English

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Requeriments :

• M.Sc. or higher Degree in Bioinformatics
• Master’s Degree in Genetics

Skills :

• Bioinformatics
• Cancer biology
• Genetics
• genomic
• Lunix/Unix
• molecular biology
• Next Generation Sequencing
• Programing in Python
• Programming in R
• RNA-seq

Areas :

• Bioinformatics

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Additional Info:
Now that you know what we're looking for in talent, let us tell you why you'd want to work at NeoGenomics:

NeoGenomics Laboratories is comprised of a national team of experts in developing and delivering laboratory diagnostic and clinical trial services with a focus in cancer. It is the common purpose of all NeoGenomics employees to save lives by improving patient CARE through Communication, Accuracy, Reliability, and Efficiency. Our staff physicians, scientists, laboratory professionals, client services representatives, and sales people team up with our clients. Together, we work to solve the medical, scientific, and logistical challenges of making precise diagnoses, aiding in bringing new therapies to market and finding the unusual hallmarks of each patient’s disease that point the way to proper treatment.

As an employer, we promise to provide you with a purpose driven mission in which you have the opportunity to save lives by improving patient care through the exceptional work you perform. Together, we will become the world's leading cancer reference laboratory.

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