Bioinformatics Scientist – Primer Design

Job ID:
Job date: 2018-02-24
End Date:

Company : Thermo Fisher Scientific 

Country :

Role : Research Scientist 


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Job Description:
When you’re part of the team at Thermo Fisher Scientific, you’ll do important work, like helping customers in finding cures for cancer, protecting the environment or making sure our food is safe. Your work will have real-world impact, and you’ll be supported in achieving your career goals.

How will you make an impact?

You’ll be part of our dynamic Bioinformatics Research and Development team in Clinical Next Generation Sequencing Group. You’ll be responsible for primer design for the development of targeted sequencing panels, pipelines and algorithms for next-generation DNA sequencing.

As the leading supplier of life science technology and related applications, we are helping life scientists understand and use the power of genomics to pursue new scientific discoveries and advance clinical research in personalized medicine. Our innovations extend Thermo Fisher’s commitment to help researchers bring new cancer diagnostics to clinic

What will you do?

  • Design assays for custom targeted sequencing panels for external and internal researchers.
  • Understand the core scientific questions and design assays to best address these questions.
  • Develop, maintain, and operate bioinformatics pipelines for assay design, data mining and analysis
  • Improve the designs by iterative analysis of the sequencing data obtained. Develop heuristic rules, optimization, and algorithms to improve the design pipeline.
  • Analyze sequence data and mine public databases for sequence content.
  • Collaborate closely with the molecular biologists, product management, sales, experimental researchers and other members of the Bioinformatics team.
  • Work closely with external customers to understand and provide the best design solution that meets their need.

How will you get there?

Education and Experience:

  • This position requires the knowledge and skills normally acquired through completion of a MS/PhD in Bioinformatics, Computational Biology, Computer Science, Genomics or related field. A minimum of three years of relevant working experience is required.
  • Experience working and developing bioinformatics production systems.
  • Experience in Perl / Python programming, shell scripting and SQL.
  • Hands-on experience with the relevant sequence analysis tools such as Blast, Clustalw and Bowtie.
  • Experience with next generation sequencing data.
Knowledge, Skills, Abilities:
  • An excellent understanding of genomic databases and their annotations (GenBank, RefSeq, ENSEMBL, dbSNP, UCSC genome browser).
  • A good understanding of the biology behind genotyping, gene expression profiling, comparative genomics and genetic mapping.
  • An appreciation of the use of statistical methods and mathematical models in the interpretation of biological data.
  • Strong communication and organization skills are required.


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Additional Info:
About Thermo Fisher Scientific:

Thermo Fisher Scientific Inc. (NYSE: TMO) is the world leader in serving science, with revenues of more than $20 billion and approximately 65,000 employees globally. Our mission is to enable our customers to make the world healthier, cleaner and safer. We help our customers accelerate life sciences research, solve complex analytical challenges, improve patient diagnostics, deliver medicines to market and increase laboratory productivity. Through our premier brands – Thermo Scientific, Applied Biosystems, Invitrogen, Fisher Scientific and Unity Lab Services – we offer an unmatched combination of innovative technologies, purchasing convenience and comprehensive services.

Thermo Fisher Scientific is an EEO/Affirmative Action Employer and does not discriminate on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability or any other legally protected status.

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