Job Description:
Genentech is inviting applications for a scientist position (rank equivalent to assistant professor in academia) in the Department of Human Genetics, which has the goal of identifying novel therapeutic targets and biomarkers. Day-to-day responsibilities will include: -Collaborating with scientists to design genetic studies. -Analysis of data (including quality control, data management) to identify variants/gene contributing to disease susceptibility and treatment outcomes. -Interpretation of findings to uncover novel therapeutic targets and biomarkers of disease heterogeneity. -Presentation of the work at internal meetings and external conferences. -Manuscript writing. -Data analysis to include: processing large-scale whole-genome/exome/RNA sequencing data, GWAS, linkage, eQTL, differential gene expression analyses, and application of functional genomic annotations and pathways/gene-networks. Focus areas include cancer immunotherapy, autoimmune, neuro-degenerative, and metabolic disorders. Who You Are: Qualified candidates will meet the following requirements. The level of the position will depend on the qualifications of the selected candidate. -PhD in a relevant discipline. -Significant relevant experience in statistical/human genetics or bioinformatics/computational biology. -Record of scientific publications in respected journals in these fields. -Core computational skills necessary to carry out the above responsibilities. -Well versed in the management and analysis of large datasets including those derived from SNP arrays, expression arrays and next-generation sequencing platforms. -Clear understanding of the analysis methods involved in large-scale genetic association studies for complex diseases (e.g. correcting for population stratification, imputation of genotypes). -Familiarity with tools and databases commonly used in genetic data analysis. -Proficiency in high-level programming languages (e.g. Perl, Python) and statistical computing (R) are highly desirable. -Knowledge of molecular biology and experience in biologic interpretation of human genetic data are a plus -Strong communication and interpersonal skills. -Highly motivated and demonstrate the ability to collaborate with experimental scientists.
Additional Info:
Genentech provides an exceptional research environment composed of internationally recognized leaders as well as state of the art core facilities with cutting edge technologies and computational resources to support all research activities. We provide a highly collaborative community and as such you will interact closely with clinical development teams and other scientists in the areas of biomarkers, bioinformatics, and research discovery departments, including Cancer Immunotherapy, Molecular Oncology, Immunology, Metabolic Disease, and Neuroscience. Who We Are: A member of the Roche Group, Genentech has been at the forefront of the biotechnology industry for more than 40 years, using human genetic information to develop novel medicines for serious and life-threatening diseases. Genentech has multiple therapies on the market for cancer & other serious illnesses. Please take this opportunity to learn about Genentech where we believe that our employees are our most important asset & are dedicated to remaining a great place to work. The next step is yours. To apply today, click on the "Apply online" button below. Genentech is an equal opportunity employer & prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital & veteran status. For more information about equal employment opportunity, visit our Genentech Careers page.[Click Here to Access the Original Job Post]
Genentech is inviting applications for a scientist position (rank equivalent to assistant professor in academia) in the Department of Human Genetics, which has the goal of identifying novel therapeutic targets and biomarkers. Day-to-day responsibilities will include: -Collaborating with scientists to design genetic studies. -Analysis of data (including quality control, data management) to identify variants/gene contributing to disease susceptibility and treatment outcomes. -Interpretation of findings to uncover novel therapeutic targets and biomarkers of disease heterogeneity. -Presentation of the work at internal meetings and external conferences. -Manuscript writing. -Data analysis to include: processing large-scale whole-genome/exome/RNA sequencing data, GWAS, linkage, eQTL, differential gene expression analyses, and application of functional genomic annotations and pathways/gene-networks. Focus areas include cancer immunotherapy, autoimmune, neuro-degenerative, and metabolic disorders. Who You Are: Qualified candidates will meet the following requirements. The level of the position will depend on the qualifications of the selected candidate. -PhD in a relevant discipline. -Significant relevant experience in statistical/human genetics or bioinformatics/computational biology. -Record of scientific publications in respected journals in these fields. -Core computational skills necessary to carry out the above responsibilities. -Well versed in the management and analysis of large datasets including those derived from SNP arrays, expression arrays and next-generation sequencing platforms. -Clear understanding of the analysis methods involved in large-scale genetic association studies for complex diseases (e.g. correcting for population stratification, imputation of genotypes). -Familiarity with tools and databases commonly used in genetic data analysis. -Proficiency in high-level programming languages (e.g. Perl, Python) and statistical computing (R) are highly desirable. -Knowledge of molecular biology and experience in biologic interpretation of human genetic data are a plus -Strong communication and interpersonal skills. -Highly motivated and demonstrate the ability to collaborate with experimental scientists.
Requeriments :
Skills :
- Bioinformatics
- Biomarker Discovery
- Computational Biology
- Genetics
- molecular biology
- Next Generation Sequencing
- Programing in Python
- Programing Skills
- Programming in PERL
- Programming in R
- RNA-seq
Areas :
Additional Info:
Genentech provides an exceptional research environment composed of internationally recognized leaders as well as state of the art core facilities with cutting edge technologies and computational resources to support all research activities. We provide a highly collaborative community and as such you will interact closely with clinical development teams and other scientists in the areas of biomarkers, bioinformatics, and research discovery departments, including Cancer Immunotherapy, Molecular Oncology, Immunology, Metabolic Disease, and Neuroscience. Who We Are: A member of the Roche Group, Genentech has been at the forefront of the biotechnology industry for more than 40 years, using human genetic information to develop novel medicines for serious and life-threatening diseases. Genentech has multiple therapies on the market for cancer & other serious illnesses. Please take this opportunity to learn about Genentech where we believe that our employees are our most important asset & are dedicated to remaining a great place to work. The next step is yours. To apply today, click on the "Apply online" button below. Genentech is an equal opportunity employer & prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital & veteran status. For more information about equal employment opportunity, visit our Genentech Careers page.[Click Here to Access the Original Job Post]