Job ID: 654814611
Job date: 2018-05-04
End Date: 2018-07-03
Company : Howard Hughes Medical Institute Country : United States Role : Other
Job date: 2018-05-04
End Date: 2018-07-03
Company : Howard Hughes Medical Institute Country : United States Role : Other
Job Description:
The Howard Hughes Medical Institute has an exciting opportunity for a Bioinformatics Specialist to join the research team in a lab at the University of Washington in Seattle, Washington. Position Purpose: The Bioinformatics Specialist will lead genome-wide analyses to investigate copy number and genomic structural variation specifically within complex regions of the human genome including regions of segmental duplications. He will work with the PI and postdoctoral fellows to develop computational pipelines using a suite of next-generation sequencing technologies, including Illumina, long-read single-molecule, real-time (SMRT) PacBio, and traditional capillary sequencing technology. He will participate in national and international consortia focused on understanding the genetic architecture of autism, assembly of primate genomes, and the characterization of human genome structural variation. Position Complexities This lab is involved in several different projects simultaneously, which requires skills in integrating data and systems. Familiarity with existing bioinformatics-specific software tools, especially data-mining of whole-genome shotgun sequence data analysis, is required. Experience in genomics research is necessary for performance of this job. The ideal candidate will independently perform scientific investigative procedures requiring application of professional judgment, interpret experimental results, guide lab members through bioinformatics methods and analyses, and prepare reports of research for presentation or publication. Dimensions and Impact to the University: This position will work in a prominent laboratory whose work impacts other researchers worldwide. High functioning will be reflected in even greater funding opportunities and enhancement of the reputation of the University as a biomedical research powerhouse. Responsibilities: (Identify the percent of time spent on each major duty, listed in decreasing order of importance. The total job duties must equal 100% regardless of the position’s % FTE.)
Additional Info:
About HHMI Howard Hughes Medical Institute (HHMI) is a science philanthropy whose mission is to advance biomedical research and science education for the benefit of humanity. We empower exceptional scientists and students to pursue fundamental questions about living systems, and work to share scientific discoveries with researchers, students, and science-curious individuals around the world. Founded in 1953 by aviator and industrialist Howard R. Hughes, HHMI is headquartered in Chevy Chase, Maryland, and employs more than 2,500 people across the U.S. Visit hhmi.org/careers to learn more about working at HHMI. HHMI is an Equal Opportunity Employer. At the Howard Hughes Medical Institute, we believe in the power of individuals to advance science through research and science education, making discoveries that benefit humanity. Learn more about how we move science forward. Visit our website at http://www.hhmi.org. [Click Here to Access the Original Job Post]
The Howard Hughes Medical Institute has an exciting opportunity for a Bioinformatics Specialist to join the research team in a lab at the University of Washington in Seattle, Washington. Position Purpose: The Bioinformatics Specialist will lead genome-wide analyses to investigate copy number and genomic structural variation specifically within complex regions of the human genome including regions of segmental duplications. He will work with the PI and postdoctoral fellows to develop computational pipelines using a suite of next-generation sequencing technologies, including Illumina, long-read single-molecule, real-time (SMRT) PacBio, and traditional capillary sequencing technology. He will participate in national and international consortia focused on understanding the genetic architecture of autism, assembly of primate genomes, and the characterization of human genome structural variation. Position Complexities This lab is involved in several different projects simultaneously, which requires skills in integrating data and systems. Familiarity with existing bioinformatics-specific software tools, especially data-mining of whole-genome shotgun sequence data analysis, is required. Experience in genomics research is necessary for performance of this job. The ideal candidate will independently perform scientific investigative procedures requiring application of professional judgment, interpret experimental results, guide lab members through bioinformatics methods and analyses, and prepare reports of research for presentation or publication. Dimensions and Impact to the University: This position will work in a prominent laboratory whose work impacts other researchers worldwide. High functioning will be reflected in even greater funding opportunities and enhancement of the reputation of the University as a biomedical research powerhouse. Responsibilities: (Identify the percent of time spent on each major duty, listed in decreasing order of importance. The total job duties must equal 100% regardless of the position’s % FTE.)
- Develop and streamline algorithms and computational tools to detect duplications, copy number variants, and single-nucleotide polymorphisms using data generated from genome sequencing projects. (30%)
- Manage genome datasets, local UCSC Genome Browser and interact with IT to optimize massively parallel computing infrastructure (2000+ CPUs) and transfer of data from and to cloud services. (20%)
- Create new programs and/or scripts, including graphical visualization software to facilitate large-scale datamining of the genome, genetic and expression databases. (20%)
- Prepare reports and presentations for research projects, including collaborations as part of international consortia. (10%)
- Train programmers and work independently as well as with trainees on research projects as assigned by the Investigator (10%)
- Provide support for PacBio Cost Center. (10%)
- Bachelors of Science degree in computer science, bioinformatics or related field or equivalent in education and experience.
- At least three years of experience developing computational methods and tools used in bioinformatics research.
- In-depth understanding of data structure and algorithm design and implementation.
- Extensive experience in two or more programming languages (C/C++, Perl, Python, Java, etc.).
- Skilled with Linux/Unix and working in a command line environment.
- Ability to perform independent analyses and report findings to both national and international collaborative groups.
- Technical proficiency and collaborative ability as well as independent thought.
- Ability to develop innovative processes to achieve goals. Reviews work activities to determine where new information could improve processes or move projects forward.
- Ability to work independently and as part of a multidisciplinary team.
- Masters of Science degree in computer science/bioinformatics or related field or equivalent in education and experience.
- At least one year of bioinformatics or related research experience in data analysis of next-generation sequencing or whole-genome shotgun data.
- Proficient with existing bioinformatics tools (e.g., BWA, GATK, BLAST, CLUSTALW, or MEGA).
Requeriments :
Skills :
- Bioinformatics
- Lunix/Unix
- Programing in C
- Programing in C++
- Programing in Python
- Programing Skills
- Programming in Java
- Programming in PERL
Areas :
Additional Info:
About HHMI Howard Hughes Medical Institute (HHMI) is a science philanthropy whose mission is to advance biomedical research and science education for the benefit of humanity. We empower exceptional scientists and students to pursue fundamental questions about living systems, and work to share scientific discoveries with researchers, students, and science-curious individuals around the world. Founded in 1953 by aviator and industrialist Howard R. Hughes, HHMI is headquartered in Chevy Chase, Maryland, and employs more than 2,500 people across the U.S. Visit hhmi.org/careers to learn more about working at HHMI. HHMI is an Equal Opportunity Employer. At the Howard Hughes Medical Institute, we believe in the power of individuals to advance science through research and science education, making discoveries that benefit humanity. Learn more about how we move science forward. Visit our website at http://www.hhmi.org. [Click Here to Access the Original Job Post]