Bioinformatics Specialist (Senior Research Assistant)

Job ID: 1194797539
Job date: 2018-01-08
End Date:

Company : Oregon Health & Science University 

Country :

Role : Other 


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Job Description:
This is a joint position between the O’Roak and Adey labs that requires a skilled bioinformatician with experience processing and analyzing “next-generation” sequencing datasets. Individual will conduct primary and secondary analyzes that will likely require writing custom scripts/programs and running standard best practice computational pipelines. Initial projects will focus on: genome analysis, targeted resequencing, de novo assembly of viral genomes, and single cell genomics.

Experience with whole-exome or genome sequencing required. Familiarity with genome assembly, statistics, population and gene databases, in silico predictive algorithms, structural variation tools, genetics and genomics is strongly preferred. Experience with RNA-seq and epigenetics data analysis (e.g. ChIP-seq, ATAC-seq, etc..) is strongly preferred. Good communication skills are required.

OHSU is a highly collaborative environment. Researchers will have the opportunity to interact/collaborate with researchers from genetics, neurosciences, the new computational biology program, and clinical research programs focused on neurodevelopmental disorders.

Highlights of Dr. O’Roak’s past research successes include: pioneering trio-based exome sequencing in simplex autism, and developing new technologies for rapid and economical targeted resequencing. His diverse research group focuses on developing and implementing cutting-edge methods and technologies for discovery and replication, molecular diagnosis, functional dissection of pathways, and targeted therapeutics for neurodevelopmental and related disorders.

Highlights of Dr. Adey’s past research include the development and utilization of a number of next-generation sequencing technologies for genomic and epigenomic profiling, including the pioneering of transposase-based next-generation sequencing technologies. His group is focused heavily on single-cell assays and includes recent publications on novel technological advances that are being applied in collaboration with the O’Roak lab and others at OHSU.

Job Requirements

Required Qualifications:

  • Bachelor's Degree with major courses in field of research and 1 to 3 years of experience in computer science or bioinformatics
  • Experience with whole-exome or genome sequencing
  • Fluent in one or more programing languages
  • Good communication skills
  • Able to work in a team and effectively communicate results to other members
Preferred Qualifications:
  • Master's degree in related field
  • Intensive training in the areas of genetics/genomics, computer science, bioinformatics
  • Familiarity with statistics, population and gene databases, in silico predictive algorithms, structural variation tools, genetics and genomics
  • Experience with RNA-seq and ChIP-seq
  • Linux cluster management and architecture


Requeriments :

Skills :

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Additional Info:
Work Schedule, Hours, FTE, Salary Range:

FTE: 1.0 FTE, Full Time

Schedule: Variable

Salary Range: Commensurate with Experience

Location: Portland, OR (Marquam Hill)

Job Type: Research

Oregon Health & Science University values a diverse and culturally competent workforce. We are proud of our commitment to being an equal opportunity, affirmative action organization that does not discriminate against applicants on the basis of any protected class status, including disability status and protected veteran status. Individuals with diverse backgrounds and those who promote diversity and a culture of inclusion are encouraged to apply. To request reasonable accommodation contact the Affirmative Action and Equal Opportunity Department at 503-494-5148 or aaeo@ohsu.edu.

How To Apply:

Apply here online. Please attach CV/Resume, cover letter and list of 3 references.

[Click Here to Access the Original Job Post]