Job ID:
Job date: 2015-05-18
End Date:
Company : NATIONAL HEALTH AND ENVIRONMENTAL EFFECTS RESEARCH LAB Country : Role : Postdoc
Job date: 2015-05-18
End Date:
Company : NATIONAL HEALTH AND ENVIRONMENTAL EFFECTS RESEARCH LAB Country : Role : Postdoc
Job Description:
Additional Info:
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| Project number: | GED-05-04-2015-07 |
| Lab/Center/Office: | NATIONAL HEALTH AND ENVIRONMENTAL EFFECTS RESEARCH LAB |
| Division: | GULF ECOLOGY DIVISION |
| Branch: | BIOLOGICAL EFFECTS AND POPULATION RESPONSE BRANCH |
| Brief description of research project: | EPA’s Office of Research and Development is using genomic and proteomic endpoints to help identify molecular pathways and changes in microbial communities connected to environmental stressors. Research will contribute to the Chemical Safety for Sustainability and Safe and Sustainable Water Resources research programs. Critical work to be performed is the development and application of advanced molecular biology tools and approaches, including proteomic and genomics, to address ongoing and future priorities in chemical risk evaluation and water quality research. The successful applicant will use bioinformatics applicable to the collection, analysis, synthesis, interpretation, classification, movement and dissemination of large and complex data sets. Data will be generated from proteomics and genomics studies designed to understand and predict changes in environmental systems resulting from chemical exposure and/or nutrient enrichment and eutrophication. Successful development of state of the science approaches to support EPA’s mission will provide sensitive indicators, predictive tools, and improved application of models designed to assess the mechanisms responsible for observed or predicted impacts to the environment and human health. Research may include but is not limited to the following: i) Developing bioinformatic pipelines to analyze proteins and genes identified in toxicity pathways in aquatic and semi-aquatic species associated with exposure to environmental contaminants; ii) Determining statistical linkages between gene/protein expression and internal dose levels of various chemicals; iii) Determining if gene/protein expression and identified toxicity pathways can be applied to interspecies and interclass toxicity translator models (i.e., fish and amphibians); iv ) Bioinformatic analyses of microbial and/or functional gene indicators of nutrient impacts to aquatic ecosystems. Bioinformatics will be utilized to evaluate DNA sequences obtained from periphyton, sediments, or other substrates. |
| Geographical location of position: | Gulf Breeze, FL |
| High priority research areas: | Development and application of approaches that use protein and gene expression data to identify toxicity pathways following exposure to environmental contaminants, and development of methods for establishing quantitative management thresholds for use in sustainable nutrient management. |
| Scientific project area: | Integrated modeling for assessment impacts of aquatic systems exposed to environmental stressors. |
| Educational requirements: | Ph.D. in Bioinformatics, Molecular or Microbial Biology, Toxicology, Biochemistry, Environmental Sciences, Biology, Mathematics, Statistics, or related field. |
| Specialized training and/or experience preferred: | The preferred candidate will have demonstrated experience in information sciences as applied to biological and ecological systems. Provide bioinformatics research expertise across genomic and proteomic disciplines and serve future cross program priorities. Strong analytical background and expertise in bioinformatics methods, as well as experience applying mathematical and statistical methods to analyze high-dimension multivariate data sets. Experience in experimental design of research employing ‘omics’ technology, employing modern molecular biological methods, interpreting genomic and/or proteomic data to solve environmental problems. |
| Projected duration of appointment: | 3 years |
| Paid relocation to EPA work location: | Yes |
| Application Period Open Date: | May 04, 2015 |
| Application Period Close Date: | Jun 08, 2015 |
| Scientific contact/Principal Investigator(s)*: | Sandy Raimondo, raimondo.sandy@epa.gov, 850-934-2424 |
Skills :
Areas :
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