Job Description:
Applications are invited for a Computational Biologist to join the Quadram Institute Bioscience in Norwich, UK. The Role: The successful post holder will develop computer software to predict rDNA sequence and copy number variation from bespoke single chromosome datasets developed in collaboration with Dr Jane Usher at the University of Exeter, using computational techniques such as variation graphs and machine learning. This will be followed by analysis of the discovered variation to enable inferences about the biological processes driving rDNA evolution to be made. Project software will ultimately be used to predict rDNA variation associated with key biological processes such as disease status and healthy ageing. The close collaboration with the Davey group at EI will also provide opportunities to work amongst computational biology groups researching a wider range of projects. The Ideal Candidate: Candidates are expected to have a PhD in a numerical discipline such as Computational Biology, Bioinformatics, Computer Science or Mathematics. Excellent computer programming skills are also required, with experience in C++ an advantage. Experience in one or more of analysis of genomic and transcriptomic datasets, algorithm design, machine learning and variation graphs would also be highly advantageous. The ability to handle complex concepts and ideas and to work independently are required, as are effective communication skills.
Additional Info:
Location: Norwich Salary: £31,250 to £38,100 per annum depending on qualifications and experience Hours: Full Time Contract Type: Fixed-Term/Contract Placed on: 16th January 2018 Closes: 28th January 2018 Background: Dr Jo Dicks at the Quadram Institute Bioscience (QIB - www.quadram.ac.uk) and Dr Robert Davey at the neighbouring Earlham Institute (EI - www.earlham.ac.uk) have been instrumental in the development of a dynamic computational research program precisely characterizing ribosomal DNA (rDNA) variation and evolution in yeast, with associated publications in leading journals such as Nature, Genome Research, Systematic Biology and Bioinformatics. The rDNA is fundamental to life, encoding elements involved in the translation of mRNA molecules to proteins. Yet despite the importance of this genomic region, the variation encompassed within and its biological significance have largely been ignored. This exciting research program is now poised to begin a new phase of research, investigating rDNA variation and expression across disparate chromosomes in yeast and wheat. Salary on appointment will be within the range £31,250 to £38,100 per annum depending on qualifications and experience. This post is for a contract of two years. For further information and details of how to apply, please visit our web site https://jobs.quadram.ac.uk or contact the Human Resources team on 01603 450462 or nbi.recruitment@nbi.ac.uk quoting reference 1003395. We are committed to equal opportunities and welcome applications from all sectors of society. The Institute supports equality of opportunity within the workplace and expects all employees to share and display these values. To support our commitment, we have a range of family, faith and diversity friendly working arrangements to help all staff achieve excellence in their area of work. As a Disability Confident employer, we guarantee to offer an interview to all disabled applicants who meet the essential criteria for this vacancy. The closing date for applications will be 28th January 2018 The Quadram Institute Bioscience is a registered charity (No. 1058499) and is an Equal Opportunities Employer.[Click Here to Access the Original Job Post]
Applications are invited for a Computational Biologist to join the Quadram Institute Bioscience in Norwich, UK. The Role: The successful post holder will develop computer software to predict rDNA sequence and copy number variation from bespoke single chromosome datasets developed in collaboration with Dr Jane Usher at the University of Exeter, using computational techniques such as variation graphs and machine learning. This will be followed by analysis of the discovered variation to enable inferences about the biological processes driving rDNA evolution to be made. Project software will ultimately be used to predict rDNA variation associated with key biological processes such as disease status and healthy ageing. The close collaboration with the Davey group at EI will also provide opportunities to work amongst computational biology groups researching a wider range of projects. The Ideal Candidate: Candidates are expected to have a PhD in a numerical discipline such as Computational Biology, Bioinformatics, Computer Science or Mathematics. Excellent computer programming skills are also required, with experience in C++ an advantage. Experience in one or more of analysis of genomic and transcriptomic datasets, algorithm design, machine learning and variation graphs would also be highly advantageous. The ability to handle complex concepts and ideas and to work independently are required, as are effective communication skills.
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Additional Info:
Location: Norwich Salary: £31,250 to £38,100 per annum depending on qualifications and experience Hours: Full Time Contract Type: Fixed-Term/Contract Placed on: 16th January 2018 Closes: 28th January 2018 Background: Dr Jo Dicks at the Quadram Institute Bioscience (QIB - www.quadram.ac.uk) and Dr Robert Davey at the neighbouring Earlham Institute (EI - www.earlham.ac.uk) have been instrumental in the development of a dynamic computational research program precisely characterizing ribosomal DNA (rDNA) variation and evolution in yeast, with associated publications in leading journals such as Nature, Genome Research, Systematic Biology and Bioinformatics. The rDNA is fundamental to life, encoding elements involved in the translation of mRNA molecules to proteins. Yet despite the importance of this genomic region, the variation encompassed within and its biological significance have largely been ignored. This exciting research program is now poised to begin a new phase of research, investigating rDNA variation and expression across disparate chromosomes in yeast and wheat. Salary on appointment will be within the range £31,250 to £38,100 per annum depending on qualifications and experience. This post is for a contract of two years. For further information and details of how to apply, please visit our web site https://jobs.quadram.ac.uk or contact the Human Resources team on 01603 450462 or nbi.recruitment@nbi.ac.uk quoting reference 1003395. We are committed to equal opportunities and welcome applications from all sectors of society. The Institute supports equality of opportunity within the workplace and expects all employees to share and display these values. To support our commitment, we have a range of family, faith and diversity friendly working arrangements to help all staff achieve excellence in their area of work. As a Disability Confident employer, we guarantee to offer an interview to all disabled applicants who meet the essential criteria for this vacancy. The closing date for applications will be 28th January 2018 The Quadram Institute Bioscience is a registered charity (No. 1058499) and is an Equal Opportunities Employer.[Click Here to Access the Original Job Post]