Job Description:
Are you looking for a patient-focused company that will inspire you and support your career? If so, be empowered to take charge of your future at Takeda. Join us as a Computational Biologist, Discovery Toxicologyin our Cambridgeoffice. Here, everyone matters and you will be a vital contributor to our inspiring, bold mission. As a Computational Biologist, Discovery Toxicologyworking on the Toxicologyteam, you will be empowered to develop and apply bioinformatics tools to analyze complex toxicology datasetsand work collaboratively on computational projects across multiple disciplinary areas, and a typical day will include: OBJECTIVES:
Additional Info:
Overview More than 30,000 Takeda employees working in more than 70 countries are committed to improving quality of life for patients, who remain at the center of everything we do. Takeda Pharmaceutical Company Limited is a global, research and development-driven organization working internally and with external partners to translate science into life-changing medicines. Takeda focuses on the core therapeutic areas of oncology, gastroenterology, central nervous system and providing vaccines that address the most important infectious diseases. Novel products, especially in oncology and gastroenterology, as well as our presence in emerging markets, fuel our growth. Takeda Pharmaceuticals U.S.A., Inc. ranks among the top 15 pharmaceutical companies in the United States. Our larger U.S. offices are in Cambridge, MA, Deerfield, IL, and San Diego, CA. Research & Development employees in our Cambridge location focus on oncology, gastroenterology, immunomodulation, biologics, translational research, and external innovation. In March 2016, we opened our newest space at 300 Massachusetts Avenue, featuring 230,000 square feet of state-of-the-art office and lab space. While Takeda is enjoying tremendous growth as an emerging global leader in the pharmaceutical industry, we remain ever mindful of our commitment to serve people worldwide by striving toward better health through leading innovation in medicine. In short, we are a passionate team doing important work that impacts patients’ lives. If you are driven to create better health and a brighter future, join us! WHAT TAKEDA CAN OFFER YOU: -401(k) with company match and Annual Retirement Contribution Plan -Tuition reimbursement -Company match of charitable contributions -Health & Wellness programs including onsite flu shots and health screenings -Generous time off for vacation and the option to purchase additional vacation days -Community Outreach Programs -Empowering Our People to Shine -Learn more at takedajobs.com. Takeda is an EEO employer of minorities, women, disabled, protected veterans.[Click Here to Access the Original Job Post]
Are you looking for a patient-focused company that will inspire you and support your career? If so, be empowered to take charge of your future at Takeda. Join us as a Computational Biologist, Discovery Toxicologyin our Cambridgeoffice. Here, everyone matters and you will be a vital contributor to our inspiring, bold mission. As a Computational Biologist, Discovery Toxicologyworking on the Toxicologyteam, you will be empowered to develop and apply bioinformatics tools to analyze complex toxicology datasetsand work collaboratively on computational projects across multiple disciplinary areas, and a typical day will include: OBJECTIVES:
- As part of the Global Discovery Toxicology Team work in interdisciplinary teams within and across Global Safety to provide safety support to early discovery teams and engage in core activities within the Discovery Toxicology group
- Work as part of a team of safety assessment scientists and more broadly DMPK, pathology, pharmacology, and medicinal chemistry experts to implement discovery toxicology strategy to enable the selection and progression of optimized drug candidates
- Apply novel toxicity mechanism-based assays and integrated models to support early target safety and chemistry evaluation.
- Integrate into early discovery project teams, assist in the identification of on- and off-target pharmacology risks and identify de-risking strategies
- Develop and apply bioinformatic tools to assist in the curation, analysis and visualization of large-scale, complex toxicological datasets from multiple sources
- Work collaboratively on computational projects across multiple disciplinary areas, including DMPK, medicinal chemistry, drug safety and pharmacology
- Design new computational biology tools and applications that are relevant to the design of drugs with the safest pharmacological profile
- Drive the improvement of early risk assessment strategies through the identification of toxicological pathways that are applicable across all therapeutic areas
- Develop and maintain global platforms that integrate internal and external bioinformatic tools and models
- Minimum of MS with 8 years of pharmaceutical experience or PhD in a scientific discipline with 3 years postdoctoral experience and/or 5+ years of experience working at a pharmaceutical company
- Passion to decrease safety related attrition in drug discovery
- Demonstrated experience and ability to work effectively in a matrix, global environment as part of a multidisciplinary team
- Broad scientific knowledge including pharmacology, toxicology, pathology, physiology and biochemistry.
- Strong interpersonal and organizational skills.
- Excellent oral and written communication skills
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Skills :
Areas :
Additional Info:
Overview More than 30,000 Takeda employees working in more than 70 countries are committed to improving quality of life for patients, who remain at the center of everything we do. Takeda Pharmaceutical Company Limited is a global, research and development-driven organization working internally and with external partners to translate science into life-changing medicines. Takeda focuses on the core therapeutic areas of oncology, gastroenterology, central nervous system and providing vaccines that address the most important infectious diseases. Novel products, especially in oncology and gastroenterology, as well as our presence in emerging markets, fuel our growth. Takeda Pharmaceuticals U.S.A., Inc. ranks among the top 15 pharmaceutical companies in the United States. Our larger U.S. offices are in Cambridge, MA, Deerfield, IL, and San Diego, CA. Research & Development employees in our Cambridge location focus on oncology, gastroenterology, immunomodulation, biologics, translational research, and external innovation. In March 2016, we opened our newest space at 300 Massachusetts Avenue, featuring 230,000 square feet of state-of-the-art office and lab space. While Takeda is enjoying tremendous growth as an emerging global leader in the pharmaceutical industry, we remain ever mindful of our commitment to serve people worldwide by striving toward better health through leading innovation in medicine. In short, we are a passionate team doing important work that impacts patients’ lives. If you are driven to create better health and a brighter future, join us! WHAT TAKEDA CAN OFFER YOU: -401(k) with company match and Annual Retirement Contribution Plan -Tuition reimbursement -Company match of charitable contributions -Health & Wellness programs including onsite flu shots and health screenings -Generous time off for vacation and the option to purchase additional vacation days -Community Outreach Programs -Empowering Our People to Shine -Learn more at takedajobs.com. Takeda is an EEO employer of minorities, women, disabled, protected veterans.[Click Here to Access the Original Job Post]