Job ID: 4567
Job date: 2017-09-14
End Date:
Company : Broad Institute Country : Role : Research Scientist
Job date: 2017-09-14
End Date:
Company : Broad Institute Country : Role : Research Scientist
Job Description:
The Broad Institute of MIT & Harvard, a world leader in genomics research, is looking for an exceptional candidate to join the Data and Research Center of the All of Us research program, 1 million-person cohort study which is part the US Precision Medicine Initiative. The successful candidate will join an interdisciplinary team of computational biologists, bioinformatics analysts, laboratory scientists and clinicians who will build the Data and Research Center. The candidate will develop computational tools and perform data analysis for projects related to All of Us and will report into Drs. Kathiresan and Philippakis. Projects may include computational and statistical analysis of whole genome sequence data, electronic health records data, statistical methods development and analysis of disease risk based on environmental exposures and genetic risk factors, as well as comparative examination of individuals’ responses to commonly used drugs to enable downstream targeted therapies. Additionally, the individual will be responsible for organizing, managing/handling, and integrating various datasets. CHARACTERISTIC DUTIES:
Additional Info:
The Broad Institute has been awarded a five-year grant to establish the Data and Research Center along with partners from Vanderbilt University and Verily Life Sciences. The Data and Research Center will acquire, organize and provide secure access to what will be one of the world’s largest and most diverse datasets for precision medicine research. The center will also provide research support for the scientific data and analysis tools for the program, helping to build a vibrant community of researchers from community colleges to top healthcare research institutions and industries, and including citizen scientists, who can propose studies using this information.The Data and Research Center at the Broad is jointly led by Dr. Kathiresan (Co-director, Program in Medical and Population Genetics) and Dr. Anthony Philippakis (Chief Data Officer), who leads the Data Sciences and Data Engineering Group. EOE / Minorities / Females / Protected Veterans / Disabilities [Click Here to Access the Original Job Post]
The Broad Institute of MIT & Harvard, a world leader in genomics research, is looking for an exceptional candidate to join the Data and Research Center of the All of Us research program, 1 million-person cohort study which is part the US Precision Medicine Initiative. The successful candidate will join an interdisciplinary team of computational biologists, bioinformatics analysts, laboratory scientists and clinicians who will build the Data and Research Center. The candidate will develop computational tools and perform data analysis for projects related to All of Us and will report into Drs. Kathiresan and Philippakis. Projects may include computational and statistical analysis of whole genome sequence data, electronic health records data, statistical methods development and analysis of disease risk based on environmental exposures and genetic risk factors, as well as comparative examination of individuals’ responses to commonly used drugs to enable downstream targeted therapies. Additionally, the individual will be responsible for organizing, managing/handling, and integrating various datasets. CHARACTERISTIC DUTIES:
- Integrating data across formats and sources by robust synchronization with existing datasets and databases
- Under general direction, developing innovative analytical methods to enable collaborators to interpret and design follow-up research
- Work with Data Sciences and Data Engineering group to develop analytical methodologies into software tools that will be widely distributed and shared with the scientific community accessing PMI data sets
- Lead and contribute to manuscript preparation as well as internal and external project-team reports
- Actively participating in project team and group meetings
- Ph.D. in computational biology, bioinformatics, statistics or other similar quantitative discipline with 1-3 years of experience required.
- Must have experience with biological datasets, preferably large scale genotyping and/or sequencing data and experience with electronic health record (EHR)
- Must have demonstrated experience designing computational methods and tools, including prior experience with algorithms relevant to computational biology, and skill
- Relevant experience or formal training in computational biology and statistics
- Demonstrated capability as highly organized, a creative problem-solver, detail-oriented, self-motivated, and able to work independently as well as within cross-functional teams
- Ability to adapt to rapidly changing and high-demand environments
- Exceptional communication skills (oral and written) as demonstrated by publications and presentations
- Experience with statistical analysis is strongly preferred
- Familiarity with a range of sequence alignment tools.
- Experience with a scientific programming environment, such as R or Matlab, is preferred
- Good understanding and practical experience in data management tools and applications
Requeriments :
Skills :
Areas :
Additional Info:
The Broad Institute has been awarded a five-year grant to establish the Data and Research Center along with partners from Vanderbilt University and Verily Life Sciences. The Data and Research Center will acquire, organize and provide secure access to what will be one of the world’s largest and most diverse datasets for precision medicine research. The center will also provide research support for the scientific data and analysis tools for the program, helping to build a vibrant community of researchers from community colleges to top healthcare research institutions and industries, and including citizen scientists, who can propose studies using this information.The Data and Research Center at the Broad is jointly led by Dr. Kathiresan (Co-director, Program in Medical and Population Genetics) and Dr. Anthony Philippakis (Chief Data Officer), who leads the Data Sciences and Data Engineering Group. EOE / Minorities / Females / Protected Veterans / Disabilities [Click Here to Access the Original Job Post]