Job ID: 575581
Job date: 2016-03-22
End Date:
Company : GlaxoSmithKline Country : Role : Research Scientist
Job date: 2016-03-22
End Date:
Company : GlaxoSmithKline Country : Role : Research Scientist
Job Description:
Basic qualifications: • Ph.D. or equivalent and post doctoral experience in human genetics, pharmacogenetics, genomics, clinical pharmacology, biology or related field. • Recognized expert knowledge in human genetics, with a publication record in peer reviewed journals and a record of leading innovative research. • Demonstrated ability to interpret genetic associations of rare and common diseases and investigate underlying genetic mechanisms. Preferred qualifications: • Excellent communication and influencing skills for working with international teams including internal business partners, external scientific community, key opinion leaders and regulatory authorities (FDA,EMEA) on genetics matters. • Excellent matrix leadership skills with demonstrated ability to work effectively across disciplines and within multidisciplinary teams. • Quantitative analytical skills and familiarity with common bioinformatics databases, resources and tools to generate and follow up testable genetic hypotheses. • Experience in the design and interpretation of laboratory-based methods to investigate the functional role of genetic variants in biology and disease. • Experience in the identification and evaluation of biomarkers of disease progression/outcomes to support drug discovery and development. • Experience in the field of pharmacogenetics to support development of medicines. Details: We are seeking an innovative and dynamic geneticist with a passion to draw on human genetics evidence to identify the next generation of new drugs to meet global medical needs. Target Sciences, led by Lon Cardon, aims to improve the number of successful late stage clinical trials by identifying and advancing drug targets with strong evidence of their role in disease biology. The team builds on major scientific and technology advances, breakthrough understanding of biological pathways, genomics and genetics, rapid progress in gene editing, informatics and the emergence of large scale human health databases. In addition Target Sciences has recently established two key strategic relationships: the Center for Therapeutic Target Validation (CTTV) in the UK and the Altius Institute for Biomedical Sciences in the US. Successful candidates will work in a multidisciplinary, collaborative and scientifically driven environment, interacting with key academic collaborators and GSK scientists to advance drug discovery and clinical development in multiple therapeutic areas. This field-leading research addresses important drug discovery and development challenges, directly impacts GSK’s R&D pipeline, and publishes results in top scientific journals. These posts may be based at either the South-East England (Stevenage) or Philadelphia (Collegeville and King of Prussia) R&D sites. The selected Director, Genetics will: • Develop and implement strategies and contribute scientific expertise and design to acquire and apply human genetic evidence to inform target selection decisions across therapy areas. • Identify and champion new drug targets collaborating with scientists within Target Sciences and therapy areas as well as leveraging external collaborations. • Drive innovation in the use of genetic/genomic technologies to influence target identification and validation. • Initiate and maintain external collaborations. • Provide leadership to the Genetics team, including coaching, mentoring, and possibly managing other scientists. Contact information: You may apply for this position online by selecting the Apply now button. If you require an accommodation or other assistance to apply for a job at GSK, please contact the GSK HR Service Centre at 1-877-694-7547 (US Toll Free) or +1 801 567 5155 (outside US). GSK is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive equal consideration for employment without regard to race, color, national origin, religion, sex, pregnancy, marital status, sexual orientation, gender identity/expression, age, disability, genetic information, military service, covered/protected veteran status or any other federal, state or local protected class. Important notice to Employment businesses/ Agencies GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.
Additional Info:
[Click Here to Access the Original Job Post]
Basic qualifications: • Ph.D. or equivalent and post doctoral experience in human genetics, pharmacogenetics, genomics, clinical pharmacology, biology or related field. • Recognized expert knowledge in human genetics, with a publication record in peer reviewed journals and a record of leading innovative research. • Demonstrated ability to interpret genetic associations of rare and common diseases and investigate underlying genetic mechanisms. Preferred qualifications: • Excellent communication and influencing skills for working with international teams including internal business partners, external scientific community, key opinion leaders and regulatory authorities (FDA,EMEA) on genetics matters. • Excellent matrix leadership skills with demonstrated ability to work effectively across disciplines and within multidisciplinary teams. • Quantitative analytical skills and familiarity with common bioinformatics databases, resources and tools to generate and follow up testable genetic hypotheses. • Experience in the design and interpretation of laboratory-based methods to investigate the functional role of genetic variants in biology and disease. • Experience in the identification and evaluation of biomarkers of disease progression/outcomes to support drug discovery and development. • Experience in the field of pharmacogenetics to support development of medicines. Details: We are seeking an innovative and dynamic geneticist with a passion to draw on human genetics evidence to identify the next generation of new drugs to meet global medical needs. Target Sciences, led by Lon Cardon, aims to improve the number of successful late stage clinical trials by identifying and advancing drug targets with strong evidence of their role in disease biology. The team builds on major scientific and technology advances, breakthrough understanding of biological pathways, genomics and genetics, rapid progress in gene editing, informatics and the emergence of large scale human health databases. In addition Target Sciences has recently established two key strategic relationships: the Center for Therapeutic Target Validation (CTTV) in the UK and the Altius Institute for Biomedical Sciences in the US. Successful candidates will work in a multidisciplinary, collaborative and scientifically driven environment, interacting with key academic collaborators and GSK scientists to advance drug discovery and clinical development in multiple therapeutic areas. This field-leading research addresses important drug discovery and development challenges, directly impacts GSK’s R&D pipeline, and publishes results in top scientific journals. These posts may be based at either the South-East England (Stevenage) or Philadelphia (Collegeville and King of Prussia) R&D sites. The selected Director, Genetics will: • Develop and implement strategies and contribute scientific expertise and design to acquire and apply human genetic evidence to inform target selection decisions across therapy areas. • Identify and champion new drug targets collaborating with scientists within Target Sciences and therapy areas as well as leveraging external collaborations. • Drive innovation in the use of genetic/genomic technologies to influence target identification and validation. • Initiate and maintain external collaborations. • Provide leadership to the Genetics team, including coaching, mentoring, and possibly managing other scientists. Contact information: You may apply for this position online by selecting the Apply now button. If you require an accommodation or other assistance to apply for a job at GSK, please contact the GSK HR Service Centre at 1-877-694-7547 (US Toll Free) or +1 801 567 5155 (outside US). GSK is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive equal consideration for employment without regard to race, color, national origin, religion, sex, pregnancy, marital status, sexual orientation, gender identity/expression, age, disability, genetic information, military service, covered/protected veteran status or any other federal, state or local protected class. Important notice to Employment businesses/ Agencies GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.
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[Click Here to Access the Original Job Post]