Job Description:
This paragraph summarizes the general nature, level and purpose of the job.
The Director of Bioinformatics for the Stanford Clinical Genomics Service will oversee a team of bioinformaticians responsible for: 1) laboratory validation studies of the bioinformatics pipeline as required by the College of American Pathologists and other regulatory agencies, 2) data analysis of Stanford Clinical Genomics Service (SCGS) cases, and 3) selection of algorithmic approaches to iteratively improve the bioinformatics pipeline. The SCGS analyzes genome sequencing and other sequencing and array-based data in an attempt to determine the molecular etiology in patients with unexplained heritable disease. With the Co-Directors of the SCGS, this individual will develop the vision and strategy of the SCGS. This individual will work closely with the Stanford Health Care IT (SHC IT) team to enable delivery of an enterprise-level genomic analysis platform. This platform includes the hardware and software infrastructure for large-scale clinical data processing. Software components include the Next Generation Sequence (NGS) data analysis pipeline; variant filtering, prioritization, and reporting support tools; relational variant databases. In addition, the Director of Bioinformatics for the Stanford Clinical Genomics Service will be responsible for implementing a bioinformatics quality management program and interfacing with various teams within the SCGS, SHC IT, and Stanford Children’s Health IT.
Essential Functions
The essential functions listed are typical examples of work performed by positions in this job classification. They are not designed to contain or be interpreted as a comprehensive inventory of all duties, tasks, and responsibilities. Employees may also perform other duties as assigned.
Employees must abide by all Joint Commission Requirements including but not limited to sensitivity to cultural diversity, patient care, patient’s rights and ethical treatment, safety and security of physical environments, emergency management, teamwork, respect for others, participation in ongoing education and training, communication and adherence to safety and quality programs, sustaining compliance with National Patient Safety Goals, and licensure and health screenings.
Employee must perform all duties and responsibilities in accordance with the C-I-CARE Standards of the Hospital. C-I-CARE is the foundation of Stanford’s patient-experience and represents a framework for patient-centered interactions.
• Serve as a single point of contact for bioinformatics requirements for SCGS.
• Responsible for defining, developing, and refining algorithmic approaches used in the bioinformatics pipeline.
• Work with SHC IT and third-parties during the development of the analysis pipeline to ensure that the pipeline meets enterprise-level requirements of SHC IT and that the cloud-based infrastructure can support the various components of the analysis pipeline. Ensure that the bioinformatics strategy is developed with consideration to program requirements, financial targets and evolving landscape of computational and regulatory aspects.
• Coordinate with SHC IT and Stanford Children’s Health IT teams to ensure those respective teams can implement Electronic Medical Record (EMR) integration, including order entry, utilization review and result reporting.
• Coordinate with SHC IT and Stanford Clinical Laboratories to ensure integration with the Laboratory Information Management System and other laboratory workflows and systems.
• Foster a collaborative culture between informatics groups in SHC, Stanford Children’s Health, School of Medicine, and greater Stanford University community.
• Ensure ongoing R&D of “best-in-class” diagnostic pipeline to keep SHC at the leading edge of diagnostics by leveraging expertise of Stanford University and Silicon Valley resources.
• Hire and manage a team of 4-6 bioinformaticians, who will be responsible for selection of algorithms to be used in the bioinformatics pipeline, validation studies, and ongoing analyses required by the SCGS. Provide technical leadership and supervision to the team. Ensure that the team is properly staffed and trained to meet its commitments.
• Maintain expertise in “best-practices” in bioinformatics and large-scale informatics methods.
• Work with regulatory bodies and standards organizations to help define standards for NGS data in the clinical lab environment.
• Work with senior management to ensure strategic plans align with the corporate goals and long-term plans. Responsible for meeting project milestones, for the quality of the scientific/engineering approach and for compliance with company processes.
• Be recognized expert both internally and externally. With approval of senior management, may present at scientific and professional meetings.
Perform other related duties as assigned. Minimum Requirements
Education: Master’s degree in a work-related field/discipline from an accredited college or university.
Experience: Ten (10) years of progressively responsible and directly related work experience.
License/Certification:
Any combination of education and experience that would likely provide the required knowledge, skills and abilities as well as possession of any required licenses or certifications is qualifying.
Knowledge, Skills, and Abilities
These are the observable and measurable attributes and skills required to perform successfully the essential functions of the job and are generally demonstrated through qualifying experience, education, or licensure/certification.
• Knowledge of Bioinformatics, Computational Biology, Mathematics, Computer Science, Physics, Engineering or related fields.
• Knowledge of algorithmic techniques common to bioinformatics (e.g., dynamic programming and graph algorithms), machine learning and statistical analysis methods (e.g., Bayesian inference, Hidden Markov Models, Principal Component Analysis).
• Knowledge of HPC and Cloud solutions.
• Knowledge of multi-million dollar budgeting for enterprise-level bioinformatics projects Ability directing complex informatics projects and bioinformatics teams.
• Strong analytical abilities and communication skills.
Physical Requirements and Working Conditions
The Physical Requirements and Working Conditions in which the job is typically performed are available from the Occupational Health Department. Reasonable accommodations will be made to enable individuals with disabilities to perform the essential functions of the job.
Job Information
Position Type: Director Reference (Job ID number): 32532
Start Date: ASAP
Duration: Full Time
Status: open
Contact Information
Stanford Health Care
Clinical Labs
Teresa Wei
twei@stanfordhealthcare.orghttp://www.stanfordhealthcarecareers.com/job/job_info/32532/E
How To Apply:Online at: http://www.stanfordhealthcarecareers.com/job/job_info/32532/E
or email resume to: twei@stanfordhealthcare.org
Additional Info:
[Click Here to Access the Original Job Post]
ISCB Job Board
Director of Bioinformatics, Stanford Clinical Genomics ServiceStanford Health CareClinical LabsUS-CA-Palo Alto Job SummaryThis paragraph summarizes the general nature, level and purpose of the job.
The Director of Bioinformatics for the Stanford Clinical Genomics Service will oversee a team of bioinformaticians responsible for: 1) laboratory validation studies of the bioinformatics pipeline as required by the College of American Pathologists and other regulatory agencies, 2) data analysis of Stanford Clinical Genomics Service (SCGS) cases, and 3) selection of algorithmic approaches to iteratively improve the bioinformatics pipeline. The SCGS analyzes genome sequencing and other sequencing and array-based data in an attempt to determine the molecular etiology in patients with unexplained heritable disease. With the Co-Directors of the SCGS, this individual will develop the vision and strategy of the SCGS. This individual will work closely with the Stanford Health Care IT (SHC IT) team to enable delivery of an enterprise-level genomic analysis platform. This platform includes the hardware and software infrastructure for large-scale clinical data processing. Software components include the Next Generation Sequence (NGS) data analysis pipeline; variant filtering, prioritization, and reporting support tools; relational variant databases. In addition, the Director of Bioinformatics for the Stanford Clinical Genomics Service will be responsible for implementing a bioinformatics quality management program and interfacing with various teams within the SCGS, SHC IT, and Stanford Children’s Health IT.
Essential Functions
The essential functions listed are typical examples of work performed by positions in this job classification. They are not designed to contain or be interpreted as a comprehensive inventory of all duties, tasks, and responsibilities. Employees may also perform other duties as assigned.
Employees must abide by all Joint Commission Requirements including but not limited to sensitivity to cultural diversity, patient care, patient’s rights and ethical treatment, safety and security of physical environments, emergency management, teamwork, respect for others, participation in ongoing education and training, communication and adherence to safety and quality programs, sustaining compliance with National Patient Safety Goals, and licensure and health screenings.
Employee must perform all duties and responsibilities in accordance with the C-I-CARE Standards of the Hospital. C-I-CARE is the foundation of Stanford’s patient-experience and represents a framework for patient-centered interactions.
• Serve as a single point of contact for bioinformatics requirements for SCGS.
• Responsible for defining, developing, and refining algorithmic approaches used in the bioinformatics pipeline.
• Work with SHC IT and third-parties during the development of the analysis pipeline to ensure that the pipeline meets enterprise-level requirements of SHC IT and that the cloud-based infrastructure can support the various components of the analysis pipeline. Ensure that the bioinformatics strategy is developed with consideration to program requirements, financial targets and evolving landscape of computational and regulatory aspects.
• Coordinate with SHC IT and Stanford Children’s Health IT teams to ensure those respective teams can implement Electronic Medical Record (EMR) integration, including order entry, utilization review and result reporting.
• Coordinate with SHC IT and Stanford Clinical Laboratories to ensure integration with the Laboratory Information Management System and other laboratory workflows and systems.
• Foster a collaborative culture between informatics groups in SHC, Stanford Children’s Health, School of Medicine, and greater Stanford University community.
• Ensure ongoing R&D of “best-in-class” diagnostic pipeline to keep SHC at the leading edge of diagnostics by leveraging expertise of Stanford University and Silicon Valley resources.
• Hire and manage a team of 4-6 bioinformaticians, who will be responsible for selection of algorithms to be used in the bioinformatics pipeline, validation studies, and ongoing analyses required by the SCGS. Provide technical leadership and supervision to the team. Ensure that the team is properly staffed and trained to meet its commitments.
• Maintain expertise in “best-practices” in bioinformatics and large-scale informatics methods.
• Work with regulatory bodies and standards organizations to help define standards for NGS data in the clinical lab environment.
• Work with senior management to ensure strategic plans align with the corporate goals and long-term plans. Responsible for meeting project milestones, for the quality of the scientific/engineering approach and for compliance with company processes.
• Be recognized expert both internally and externally. With approval of senior management, may present at scientific and professional meetings.
Perform other related duties as assigned. Minimum Requirements
Education: Master’s degree in a work-related field/discipline from an accredited college or university.
Experience: Ten (10) years of progressively responsible and directly related work experience.
License/Certification:
Any combination of education and experience that would likely provide the required knowledge, skills and abilities as well as possession of any required licenses or certifications is qualifying.
Knowledge, Skills, and Abilities
These are the observable and measurable attributes and skills required to perform successfully the essential functions of the job and are generally demonstrated through qualifying experience, education, or licensure/certification.
• Knowledge of Bioinformatics, Computational Biology, Mathematics, Computer Science, Physics, Engineering or related fields.
• Knowledge of algorithmic techniques common to bioinformatics (e.g., dynamic programming and graph algorithms), machine learning and statistical analysis methods (e.g., Bayesian inference, Hidden Markov Models, Principal Component Analysis).
• Knowledge of HPC and Cloud solutions.
• Knowledge of multi-million dollar budgeting for enterprise-level bioinformatics projects Ability directing complex informatics projects and bioinformatics teams.
• Strong analytical abilities and communication skills.
Physical Requirements and Working Conditions
The Physical Requirements and Working Conditions in which the job is typically performed are available from the Occupational Health Department. Reasonable accommodations will be made to enable individuals with disabilities to perform the essential functions of the job.
Job Information
Position Type: Director Reference (Job ID number): 32532
Start Date: ASAP
Duration: Full Time
Status: open
Contact Information
Stanford Health Care
Clinical Labs
Teresa Wei
twei@stanfordhealthcare.orghttp://www.stanfordhealthcarecareers.com/job/job_info/32532/E
How To Apply:Online at: http://www.stanfordhealthcarecareers.com/job/job_info/32532/E
or email resume to: twei@stanfordhealthcare.org
Skills :
Areas :
Additional Info:
[Click Here to Access the Original Job Post]