Bioinformatics Scientist, Cancer Immunology Employer Genentech, Inc. Location South San Francisco, California Salary DOE Posted June 21 2016 Discipline Life Sciences, Bioinformatics, Cancer Research Send Save Apply
Join a Team that Lives to Improve Lives
People come to Genentech from across disciplines and across the world to solve our most challenging medical conditions. You’ll find inspiration in our passion for biotechnology, our purpose to positively impact the lives of millions of patients and our dedication to our people. Joining Genentech means being part of a tradition of inquiry that will change the world. It means embracing our failures as much as our successes. It requires a willingness to look beyond the edge of what's possible. And a focus on doing the day-to-day work that makes great science happen.
The following opportunity exists in our South San Francisco, CA headquarters:
Bioinformatics Scientist, Cancer Immunology
Description
Recently, exciting developments at Genentech and elsewhere have raised the possibility of leveraging the human immune system for effective and durable control of cancer. Genentech seeks a talented and highly motivated bioinformatic scientist to pursue research projects in collaboration with our Cancer Immunology Department, and to contribute to the identification and development of the next generation of immune-based cancer therapies.
The primary focus will be on generation and interpretation of high-throughput genomic and other molecular data that increase our understanding of, for example:
The degree and nature of immune infiltration in the tumor microenvironment; Mechanisms by which tumors avoid immune surveillance; The impact of mutation or gene expression dysregulation on tumor neo-antigen presentation; and Local or circulating biomarkers which predict response to immunomodulatory drugs or therapies.Emphasis is on basic research, but with a direct connection to the clinic and to Genentech’s drug and biomarker development initiatives.
The successful candidate will work with interdisciplinary teams, carry out data analysis and integration across various domains, and apply best-in-class algorithms — or develop new algorithms — that directly address the motivating biological and clinical questions. Regular publication of both scientific and methodological results is strongly encouraged. Finally, the successful candidate will be able to effectively present complex results in a clear and concise manner that is accessible to a diverse audience of quantitative, experimental, and clinical scientists.
There is potential for a management/supervisory role for candidates who are more advanced in their careers.
Who You Are
In hiring new employees, we look for people who are also inspired by our mission and who would fit in well with the collaborative, rigorous and entrepreneurial spirit of the company culture. Because we know that employees are critical to our success in bringing novel medicines to patients, we are dedicated to remaining a great place to work and to providing employees with programs, services and benefits that allow them to bring the best to the business and to their personal lives.
The ideal candidate for this role will possess the following qualifications:
PhD in bioinformatics, biostatistics, computational biology or similar, with a strong publication record. Alternately, a PhD in molecular biology, immunology, etc. combined with a very strong record of high-throughput data analysis, supported by publication in this area. A solid understanding of the relevant concepts in cancer biology and genetics, or in immunology. Enthusiasm for learning more. Broad experience with data generated by one or more high-throughput molecular assays: microarrays, next-generation sequencing, multiplexed qPCR, flow cytometry, mass spectrometry proteomics, etc. An understanding of the statistical principles behind current best practices in high-throughput molecular data analysis. Strong experience in the use of a high-level programming language such as R, MATLAB, Python or Perl for complex data analysis. Exceptionally strong communication, data presentation and visualization skills. Ability to work both independently and collaboratively, and to handle several concurrent, fast-paced projects.A Job with Benefits Beyond the Benefits
No matter who you are or what role you play, you’ll help change the face of medicine and make a real difference in the lives of people facing the most challenging medical conditions. Plus, you’ll thrive in our one-of-a-kind culture, where diversity is celebrated, employees are valued for their contributions and we all serve as advocates for change who continually find ways to do things better.
The next step is yours. To apply today, click on the "Apply" button below.
Genentech, a member of the Roche Group, has multiple medicines on the market for cancer and other serious illnesses.
Genentech is an Equal Opportunity Employer: Minorities/Women/Disability/Veteran
Apply link: http://www.gene.com/careers/find-a-job/apply/00442290?src=JB-12582
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Skills :
- Bioinformatics
- Biology
- Cancer biology
- Computational Biology
- Genetics
- Microarray
- Programing in Python
- Programming in Matlab
- Programming in PERL
- Programming in R
- Statistics
Areas :
Additional Info:
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