Job date: 2016-02-24
End Date:
Company : Imperial College London Country : Role : Faculty
Imperial BRC Genomics Facility
Investigative Medicine Section
Division of Diabetes, Endocrinology and Metabolism
Department of Medicine
LEAD BIOINFORMATICIAN
Salary range: £43,980- £53,160 per annum
Full-time, fixed-term until 31 March 2017
Hammersmith Campus
Applications are invited for a skilled and motivated Lead Bioinformatician to join the NIHR Imperial BRC Genomics Facility on the Hammersmith Campus. The Facility provides state-of-the-art laboratory and computational support for translational research that harnesses genome information to advance disease diagnostics, prognosis and treatment. The Facility provides access to the latest next-generation sequencing (NGS) platforms including the Illumina HiSeq and MiSeq. It is responsible for the management and processing of NGS data and carries out bioinformatics analysis of large-scale genomic data sets. It develops and maintains computational workflows for NGS data processing and analysis utilising cutting edge bioinformatics tools and high-performance computing resources.
The post is funded by the Imperial Biomedical Research Centre (BRC) to support the investigation of the genetic basis of common and rare human diseases using state-of-the-art genome technologies. The successful applicant will lead the bioinformatics support within the Facility and work with clinicians and scientists from groups across the Faculty of Medicine and the BRC Genomics Facility to analyse large-scale genomic datasets predominantly obtained by NGS based approaches such as whole-genome and exome re-sequencing, RNA-seq and ChIP-seq. The post holder will carry out the analysis of next-generation sequencing data and supervise the work of junior bioinformaticians in the Facility. Activities will include quality control and mapping of NGS data for variant detection, transcription profiling or epigenetic modification detection; integration of genomic datasets with public and commercial biomedical data sources for annotation and interpretation; development, maintenance and optimisation of analysis pipelines and procedures. The ability to make strategic contributions to experimental design and assist clinicians and scientists with data interpretation are key requirements of the post.
The ideal candidate will have a degree in a biomedical science and an equivalent qualification and proven track record in bioinformatics or a closely related discipline. Applicants must have a sound understanding of the application of genome technologies and bioinformatics in the context of genomics and genetics and practical experience with the processing and analysis of large genomic, preferably next-generation sequencing datasets. The ability to communicate effectively in a multi-disciplinary research environment is essential. Experience of staff supervision will be advantageous.
Informal enquiries are welcome and can be made to Professor Jorge Ferrer (tel: +44 (0)20 759 40968, email: jorge.ferrer@imperial.ac.uk). For more information on the Imperial BRC Genomics Facility please visit http://www.imperial.ac.uk/genomicsfacility.
The College cannot normally apply for a Certificate of Sponsorship for this post under Tier 2 of the UK Border Agency’s Points Based System. Any candidate, who is considering applying for this position and requires sponsorship, must ensure that they are able to obtain permission to work in the UK through an appropriate immigration route.
Our preferred method of application is online via our website via the Apply through website button (please select “Job Search” then enter the job title or vacancy reference number into “Keywords”). Please complete and upload an application form as directed quoting reference number HM2016037.
Alternatively, if you are unable to apply online, please email m.badiani@imperial.ac.uk to request an application form.
Closing date: 10 March 2016 (Midnight GMT).
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