Manager, Statistical Consulting, Target Sciences – GlaxoSmithKline – Collegeville, PA

Job ID: 5756
Job date: 2016-07-15
End Date:

Company : GlaxoSmithKline 

Country :

Role : Research Scientist 


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Job Description:
Basic qualifications:

MSc in statistics or a related field, e.g. bioinformatics with emphasis in statistics

Preferred qualifications:

PhD in statistics or a related field, e.g. bioinformatics with emphasis in statistics
Significant experience as a consulting statistician, collaborating with scientists from other disciplines
Strong oral and written communication skills

Demonstrated ability to
• Identify existing or develop new statistical methods to improve the design, analysis, and interpretation of scientific studies
• Evaluate, recommend, and implement statistical tools for addressing scientific problems
• Deliver analytical and consulting support for the design, analysis, and interpretation of studies across multiple scientific disciplines
• Take a leadership role in multi-disciplinary teams
• Build and maintain relationships with customer groups
• Drive the adoption of statistical best practice within R&D
• Lead initiatives within a statistics team to develop internal capability

Interest in continually learning and applying new statistical skills
Knowledge of some of the following topics
• In statistics: experimental design, mixed models, Bayesian methods, linear and nonlinear regression, repeated measures, high-dimensional problems as found in ‘omics analyses
• In biology: genomics, transcriptomics, proteomics, disease biology, cellular and animal models

Details:

Selecting the targets on which to conduct long-term, expensive research is one of the most important decisions in drug discovery. Poor choices are often not realized until years later when programs fail in clinical trials. Recent advances in genetics, genomics, cell biology and informatics have the potential to improve the understanding of target biology dramatically and therefore, to improve target progression decisions. To take advantage of this opportunity, GSK recently formed a new Target Sciences group, bringing together scientists from genetics, bioinformatics, statistics, and cellular and molecular biology. Cross-disciplinary Target Sciences teams will work in close partnership with other GSK drug discovery groups and the academic community, e.g. through the ground-breaking Centre for Therapeutic Target Validation (http://www.targetvalidation.org/), to advance the science of target selection and validation. We now have a number of job opportunities in the Target Sciences Statistics team – opportunities to collaborate with other scientists to advance exciting, innovative scientific programs with the potential to improve the lives of millions of people.

The selected Manager, Statistical Consulting will
• Use a wide range of statistical methods to address diverse statistical problems in drug discovery
• Influence scientists and managers to use statistical tools and thinking to advance GSK research programs
• Identify existing statistical methods or develop new ones to improve the designs, analyses, and interpretations of GSK studies
• Deliver sound statistical solutions to GSK projects and research units
• Provide leadership within the statistics team

The position requires good technical and communication skills, continual learning of statistics and biology, and the ability to work with scientists from varied backgrounds. Successful consultants are innovative, pragmatic, and flexible, thriving in a dynamic, collegial environment with frequent new challenges.

*LI-GSK

Contact information:

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