Job ID: 224530BR
Job date: 2017-10-10
End Date:
Company : Novartis Country : Role : Research Scientist
Job date: 2017-10-10
End Date:
Company : Novartis Country : Role : Research Scientist
Job Description:
The successful candidate will serve as a biomarker liaison with clinical teams in Translational Clinical Oncology and Oncology Global Development, including the following responsibilities: We are seeking a bioinformatics investigator to accelerate the development of immuno-oncology therapies.
Additional Info:
The Next Generation Diagnostics (NGDx) group in NIBR Oncology has the mission of enabling an in-depth understanding of the molecular basis of therapeutic response for individual cancer patients using cutting-edge technologies. The group generates sequencing data from thousands of oncology clinical samples, which are then analyzed with internal bioinformatics pipelines.[Click Here to Access the Original Job Post]
The successful candidate will serve as a biomarker liaison with clinical teams in Translational Clinical Oncology and Oncology Global Development, including the following responsibilities: We are seeking a bioinformatics investigator to accelerate the development of immuno-oncology therapies.
- Collaborate with Precision Medicine Directors on the design and execution of biomarker profiling studies in clinical trials
- Manage the workflow of sample processing and data transfer, in collaboration with project managers and data engineers
- Assess the utility of candidate biomarkers, such as tumor mutation burden, circulating tumor DNA, RNA signatures, TCR clonality, and cytokines
- Develop analytical approaches for innovative technologies, such as single-cell RNA-seq
- Influence departmental leaders on technology development and deployment
- Mentor junior scientists on data analysis and scientific communication
- Ph.D. in bioinformatics, immunology, molecular biology, computer science, statistics, or related field with 3+ years of experience analyzing next-generation sequencing data
- Solid understanding of cancer genetics and immunology
- Demonstrated experience with analytical methods for DNA-seq and RNA-seq data
- Demonstrated statistical and analytical ability with programming expertise in R
- Effective prioritization among multiple projects
- Excellent interpersonal and communication skills; proven ability to work effectively within a team
- The ideal candidate would also have experience with: Linux tools; Python programming; high-performance computing clusters; single-cell RNA-seq
Requeriments :
Skills :
- Cancer biology
- DNA sequencing
- Genetics
- HPC
- immunology
- Lunix/Unix
- Next Generation Sequencing
- Programing in Python
- Programming in R
- RNA-seq
- Statistics
Areas :
Additional Info:
The Next Generation Diagnostics (NGDx) group in NIBR Oncology has the mission of enabling an in-depth understanding of the molecular basis of therapeutic response for individual cancer patients using cutting-edge technologies. The group generates sequencing data from thousands of oncology clinical samples, which are then analyzed with internal bioinformatics pipelines.[Click Here to Access the Original Job Post]