Job Description:
At the University of Bergen, Faculty of Medicine and Dentistry, Department of Clinical Medicine, Research Group “Translational Science in Neurodegeneration and Aging (TSNA)” ( http://www.uib.no/en/rg/neurodegeneration ), there is a vacant full-time temporary position as PhD-candidate in bioinformatics and integromics for a period of three (3) years. The position is linked to the project “Using multidimensional integration of biological systems to unravel the pathogenesis of Parkinson’s disease”, financed by the Bergen Research Foundation and the Research Council of Norway. Parkinson’s disease (PD) is a major cause of death and disability and has a worldwide socioeconomic impact. It affects ~2% of the population above the age of 65 and its prevalence increases dramatically as the population ages reaching ~4% of those above the age of 85 years. Despite two centuries of scientific endeavor, the molecular mechanisms underlying Parkinson’s disease (PD) remain unknown. Reductionist approaches focusing on single risk factors have failed to uncover disease pathways that can be targeted by therapies. Thus, having no understanding of the processes underlying disease initiation and progression, we are unable to develop effective therapies and patients confront a future of progressive disability and premature death. The aim of this project is to decipher the molecular pathogenesis of PD, using a holistic approach to integrate genomic, environmental and clinical information into a single, unifying model. The candidate will work in a fully funded and structured research project employing cutting-edge bioinformatic analyses of genomic and epigenomic data from patient brain-tissue, in order to elucidate novel molecular pathways underlying the pathogenesis and progression of PD. Main tasks will include integrative analyses of large-scale data sets including whole exome and genome sequencing, whole DNA-methylome, ChIP-sequencing of diverse targets and RNA sequencing. The candidate will work closely with the PI and a senior researcher in bioinformatics who has the required expertise and will supervise the candidate “hands-on”. The TSNA group includes both clinicians and basic scientists devoted to the study of neurodegenerative disorders. We have well-equipped laboratory facilities and full access to bioinformatics labs with state-of-the-art analysis tools. We also have access to a wide array of university platforms covering microscopy, metabolomics, transcriptomics and proteomics. The candidate will interact directly with a highly competitive and stimulating research environment including neurologists, pathologists, geneticists and bioinformaticians. This position is ideal for candidates interested in highly translational research in the field of aging and neurodegeneration. This post will offer substantial opportunities for career development and growth. Qualifications: We are seeking a talented young scientist holding an MSc or equivalent degree in computational biology, mathematics, physics or similar disciplines. The following qualifications will be prioritized:
Additional Info:
The University of Bergen (UiB) is an internationally recognised research university with more than 14,000 students and close to 3,500 employees at six faculties. The university is located in the heart of Bergen. Our main contribution to society is excellent basic research and education across a wide range of disciplines. For further information about the project and the position, please contact Dr Charalampos Tzoulis, phone: + 47 55 97 50 58 or +47 55 97 50 45, e-mail: Charalampos.Tzoulis@uib.no We can offer: The salary will be paid in accordance with level 50 (code 1017/pay framework 20.8) on the government salary scale, at present NOK 432 700 gross p.a. for a full time position. Further increases in salary will be based on seniority in the position. For applicants who have completed their internships, salary level 52, at present NOK 446 900 gross p.a. for a full time position. Medical specialist start on wage level 58 (code 1017/ pay framework 20.15), at present NOK 494 800 gross p.a. for a full time position A good pension scheme in the Norwegian Public Service Pension Fund A position in an inclusive workplace (IA enterprise)
At the University of Bergen, Faculty of Medicine and Dentistry, Department of Clinical Medicine, Research Group “Translational Science in Neurodegeneration and Aging (TSNA)” ( http://www.uib.no/en/rg/neurodegeneration ), there is a vacant full-time temporary position as PhD-candidate in bioinformatics and integromics for a period of three (3) years. The position is linked to the project “Using multidimensional integration of biological systems to unravel the pathogenesis of Parkinson’s disease”, financed by the Bergen Research Foundation and the Research Council of Norway. Parkinson’s disease (PD) is a major cause of death and disability and has a worldwide socioeconomic impact. It affects ~2% of the population above the age of 65 and its prevalence increases dramatically as the population ages reaching ~4% of those above the age of 85 years. Despite two centuries of scientific endeavor, the molecular mechanisms underlying Parkinson’s disease (PD) remain unknown. Reductionist approaches focusing on single risk factors have failed to uncover disease pathways that can be targeted by therapies. Thus, having no understanding of the processes underlying disease initiation and progression, we are unable to develop effective therapies and patients confront a future of progressive disability and premature death. The aim of this project is to decipher the molecular pathogenesis of PD, using a holistic approach to integrate genomic, environmental and clinical information into a single, unifying model. The candidate will work in a fully funded and structured research project employing cutting-edge bioinformatic analyses of genomic and epigenomic data from patient brain-tissue, in order to elucidate novel molecular pathways underlying the pathogenesis and progression of PD. Main tasks will include integrative analyses of large-scale data sets including whole exome and genome sequencing, whole DNA-methylome, ChIP-sequencing of diverse targets and RNA sequencing. The candidate will work closely with the PI and a senior researcher in bioinformatics who has the required expertise and will supervise the candidate “hands-on”. The TSNA group includes both clinicians and basic scientists devoted to the study of neurodegenerative disorders. We have well-equipped laboratory facilities and full access to bioinformatics labs with state-of-the-art analysis tools. We also have access to a wide array of university platforms covering microscopy, metabolomics, transcriptomics and proteomics. The candidate will interact directly with a highly competitive and stimulating research environment including neurologists, pathologists, geneticists and bioinformaticians. This position is ideal for candidates interested in highly translational research in the field of aging and neurodegeneration. This post will offer substantial opportunities for career development and growth. Qualifications: We are seeking a talented young scientist holding an MSc or equivalent degree in computational biology, mathematics, physics or similar disciplines. The following qualifications will be prioritized:
- Fluency in Unix-based environments and experience with programming and/or scripting (e.g. C/C++, Python, R, etc.)
- Familiarity with univariate/multivariate statistical methods
- Background in Machine Learning and/or Big Data analysis will be considered an advantage
- Knowledge in biology and genomics basics
- Previous experience with DNA/RNA sequencing data analysis
- Previous experience in analyses and integration of epigenomic information will be considered an advantage
- The candidate must be fluent in spoken and written English
Requeriments :
Skills :
- Biology
- DNA sequencing
- genomic
- Lunix/Unix
- Machine Learning
- Programing in C
- Programing in C++
- Programing in Python
- Programing Skills
- Programming in R
- RNA-seq
- Statistics
Additional Info:
The University of Bergen (UiB) is an internationally recognised research university with more than 14,000 students and close to 3,500 employees at six faculties. The university is located in the heart of Bergen. Our main contribution to society is excellent basic research and education across a wide range of disciplines. For further information about the project and the position, please contact Dr Charalampos Tzoulis, phone: + 47 55 97 50 58 or +47 55 97 50 45, e-mail: Charalampos.Tzoulis@uib.no We can offer: The salary will be paid in accordance with level 50 (code 1017/pay framework 20.8) on the government salary scale, at present NOK 432 700 gross p.a. for a full time position. Further increases in salary will be based on seniority in the position. For applicants who have completed their internships, salary level 52, at present NOK 446 900 gross p.a. for a full time position. Medical specialist start on wage level 58 (code 1017/ pay framework 20.15), at present NOK 494 800 gross p.a. for a full time position A good pension scheme in the Norwegian Public Service Pension Fund A position in an inclusive workplace (IA enterprise)
/ Good welfare benefits
For more information regarding what the University of Bergen can offer its employees please visit: http://www.uib.no/en/poa/74243/what-can-university-bergen-offer-its-employees Recruitment to state employment: State employment shall reflect the diversity of the population at large to the highest possible degree. The University of Bergen has therefore adopted a personnel policy objective to ensure that we achieve a balanced age and sex composition and the recruitment of persons of various ethnic backgrounds and persons with disabilities. Persons of different ethnic backgrounds and persons with disabilities are therefore encouraged to apply for the position. The successful applicant must comply with the guidelines that apply to the position at any given time. The University of Bergen applies the principles of public openness when recruiting staff to scientific positions. Information about the applicant may be made public even though the applicant has requested not to be named in the list of applicants. The applicant will be notified if her/his request is not respected. How to apply: The application must contain: A brief letter of application stating your motivation for the position, why you are applying and why the position is perfect for you A Curriculum Vitae with a complete review of all academic education and professional experience Certified copies of diplomas and transcripts of grades. Applicants whose education is from another country than Norway, need to also attach a certified translation of the diploma and transcript of grades to English or a Scandinavian language, if the original is not in any of these languages. It is required that the applicant enclose a confirmation from NOKUT that the education in question is of a scope and level that corresponds to the level of a Norwegian master’s degree. Please see www.nokut.no/en for more information about NOKUT’s general recognition Complete list of publications and scientific work you want to be evaluated Two referees (name and contact information) Please send your application with attachments electronically via Jobbnorge by clicking on the button marked “Apply for this job”. The applications will be sent electronically to the assessment committee. Please notice that the applications will be assessed only on the basis of information available in Jobbnorge when the deadline expires. It is the applicant`s responsibility to ensure that all relevant attachments are submitted by the deadline. Please notice that applications sent by e-mail will not be considered. Further information about our employment process can be found here: Closing date for applications: 20 July 2017… [Click Here to Access the Original Job Post]