PhD or PostDoc – Bioinformatics in Stem Cell Biology

Job ID: 5543
Job date: 2016-05-12
End Date:

Company : University Hospital RWTH Aachen 

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Role : Postdoc  | Student 


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Job Description:

The Institute for Biomedical Engineering – Cell Biology at RWTH Aachen University Medical School is offering a position for a Bioinformatic Scientist (PhD Student or Postdoc; m/f) starting as soon as possible. We offer a position, which is initially limited for 2 years with the option for extension. The salary is based on the German public service salary scale (TV-L).

We are analyzing mechanisms of cellular differentiation in various types of stem cells – particularly embryonic stem cells, induced pluripotent stem cells, hematopoetic stem cells, mesenchymal stem cells, and dendritic cells. To this end, we are using own and public datasets that were generated by next generation sequencing (e.g. DNA-Seq, Chip-Seq, RNA-Seq) or microarrays (gene expression arrays and DNA-methylation platforms). The position is for a talented and motivated bioinformatics scientist that interacts closely with Wet-lab scientists of the groups of Prof. Martin Zenke (http://www.molcell.rwth-aachen.de) and Prof. Wolfgang Wagner (www.stemcellbiology.ukaachen.de). Particular focus is on epigenetic changes – e.g. histone modifications or DNA-methylation changes during differentiation, disease and aging. The lab will also validate and address bioinformatics hypotheses by genome editing technologies, such as CRISPR/Cas.

Furthermore, bioinformatics research will be performed in collaboration with our colleagues at the IZKF Research Group Computational Biology (Dr. Ivan Costa; http://costalab.org) and the Joined Research Center for Computational Biomedicine at RWTH Aachen University (Professors Andreas Schuppert and Julio Saez-Rodriguez; www.combine.rwth-aachen.de) – thus, there is an excellent environment for your research.


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