Job Description:
Specific Responsibilities:
The successful candidate for this Post-Doctoral position will analyze HCV deep sequencing data to evaluate development of drug resistance to pan-genotypic anti-HCV compounds. The post-doctoral fellow will be researching relation between treatment response and the dynamics of HCV viral quasispecies in patients undergoing treatment with investigational HCV compounds. The project will be focused on analyzing large sequencing data sets from clinical trials, performing phylogenetic analyses to look at evolution of HCV drug resistance, evaluating relationship between HCV viral diversity and treatment outcome. In addition, he/she will be a part of collaborative efforts such as investigation of mechanism of drug action and drug resistance, HCV RNA detection in liver explant tissues and others.
The candidate will work with scientists within the Clinical Virology group and is expected to develop independence relating to design, execution and interpretation of experiments. She/he will actively participate in group meetings including presentation of experimental approaches and results. Organizational skills in data management are essential. A PhD is required in a relevant scientific discipline, such as molecular biology/virology/bioinformatics. A strong record of scientific excellence as evidenced by publications in peer-reviewed scientific journals is a plus. Excellent verbal and written communication skills and interpersonal skills are required. The candidate must show a high level of motivation and scientific curiosity driving her/his research, but also must be able to function effectively in a collaborative setting for some aspects of the project. She/he demonstrates technical excellence, detailed knowledge of relevant scientific literature, regular exchange of feedback with others and independent thought in evaluating experimental design and research strategy.
Essential Duties and Job Functions:
Conducts scientific research for the development of drug resistance in support of investigational and marketed drugs. Applies the principles and techniques of related scientific specialty to potential inventions, products and problems. Works under supervision of more senior scientists on development of novel state-of-the art data analysis algorithms to characterize viral evolution and drug resistance development. Assists in planning, designing, implementing, and analyzing laboratory experimentation to advance scientific knowledge of viral drug resistance. May advise research associates or members of project teams in the initiation and execution of laboratory.
Requirements
Knowledge, Experience and Skills:
- PhD in molecular biology/virology/bioinformatics or related scientific discipline is required.
- Ability in developing methods, techniques and evaluation criteria for obtaining results. Broad knowledge of state-of-the art principles and theories, applying such knowledge to the research direction that supports company interests.
-Technical proficiency, scientific creativity, collaboration with others and independent thought in suggesting experimental design and research strategy.
- Good verbal communication skills and interpersonal skills are required. Must be able to participate in highly effective teams.
- Typically no work experience is required beyond laboratory experience.
Additional Info:
[Click Here to Access the Original Job Post]
Specific Responsibilities:
The successful candidate for this Post-Doctoral position will analyze HCV deep sequencing data to evaluate development of drug resistance to pan-genotypic anti-HCV compounds. The post-doctoral fellow will be researching relation between treatment response and the dynamics of HCV viral quasispecies in patients undergoing treatment with investigational HCV compounds. The project will be focused on analyzing large sequencing data sets from clinical trials, performing phylogenetic analyses to look at evolution of HCV drug resistance, evaluating relationship between HCV viral diversity and treatment outcome. In addition, he/she will be a part of collaborative efforts such as investigation of mechanism of drug action and drug resistance, HCV RNA detection in liver explant tissues and others.
The candidate will work with scientists within the Clinical Virology group and is expected to develop independence relating to design, execution and interpretation of experiments. She/he will actively participate in group meetings including presentation of experimental approaches and results. Organizational skills in data management are essential. A PhD is required in a relevant scientific discipline, such as molecular biology/virology/bioinformatics. A strong record of scientific excellence as evidenced by publications in peer-reviewed scientific journals is a plus. Excellent verbal and written communication skills and interpersonal skills are required. The candidate must show a high level of motivation and scientific curiosity driving her/his research, but also must be able to function effectively in a collaborative setting for some aspects of the project. She/he demonstrates technical excellence, detailed knowledge of relevant scientific literature, regular exchange of feedback with others and independent thought in evaluating experimental design and research strategy.
Essential Duties and Job Functions:
Conducts scientific research for the development of drug resistance in support of investigational and marketed drugs. Applies the principles and techniques of related scientific specialty to potential inventions, products and problems. Works under supervision of more senior scientists on development of novel state-of-the art data analysis algorithms to characterize viral evolution and drug resistance development. Assists in planning, designing, implementing, and analyzing laboratory experimentation to advance scientific knowledge of viral drug resistance. May advise research associates or members of project teams in the initiation and execution of laboratory.
Requirements
Knowledge, Experience and Skills:
- PhD in molecular biology/virology/bioinformatics or related scientific discipline is required.
- Ability in developing methods, techniques and evaluation criteria for obtaining results. Broad knowledge of state-of-the art principles and theories, applying such knowledge to the research direction that supports company interests.
-Technical proficiency, scientific creativity, collaboration with others and independent thought in suggesting experimental design and research strategy.
- Good verbal communication skills and interpersonal skills are required. Must be able to participate in highly effective teams.
- Typically no work experience is required beyond laboratory experience.
Requeriments :
Skills :
Areas :
Additional Info:
[Click Here to Access the Original Job Post]