Postdoctoral Fellow – Computational/Mathematical

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Job date: 2014-10-02
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Company : Wellcome Trust Sanger Institute 

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Role : Postdoc 


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Job Description:
Salary range: £29829 to £37393 per annum dependent on experience plus excellent benefits An exciting opportunity has arisen for a Postdoctoral Fellow to undertake research in the development of novel mathematical and computational methods for understanding gene expression. This could involve transcription factor binding, epigenomic landscapes, RNA folding, or stochastic models of gene expression. The successful candidate will be required to develop into a software package a mathematical/statistical/computational framework that can be used by the wider scientific community. Processing and analysing of large complex sets of data are an essential element of this role as is being able to work with tight deadlines and changing priorities. The postholder must also be adept at working within a team and the wider Scientific community. Technological advances in recent years have transformed molecular biology by providing large amounts of high-throughput data, such as bisulfide sequencing, ChIP-seq, RNA-seq, mass-spec, and many others. These data sets open up new and exciting possibilities to develop quantitative models of gene regulation. Quantitative models will help further our understanding of the basic mechanisms of gene regulation, and they will also be of critical importance for researchers developing novel treatments for the many diseases (including cancer and many neurological disorders) where aberrant gene regulation is a causal factor. Postdoctoral Fellows are typically in their first or second postdoctoral position as part of a period of early career research training.  The post is a three year fixed-term contract. Essential Skills

  • PhD in mathematics, statistics, computer science, biology or physical sciences
  • Ability to work as part of a team
  • Good programming skills
  • Experience in mathematical modelling
  • Good communication skills
  • Motivation to learn about genomics and molecular biology
Ideal Skills
  • Experience in bioinformatics and analysis of next generation sequencing data
  • Knowledge of genomics and molecular biology
Other information The Genome Campus is a 100-acre estate south of Cambridge in the grounds of Hinxton Hall.  Nestled in the quiet countryside of these landscaped gardens are two world-class research facilities: the Wellcome Trust Sanger Institute and the European Bioinformatics Institute (EBI).  The site has become the British hub of biomedical science.  The Campus is also home to the Wellcome Trust Advanced Course and Scientific Conferences programme and the Wellcome Trust Conference Centre. In addition to its peaceful location the campus offers excellent facilities including a start of the art data centre, gym, two cafes, a nursery, dining facilities, a cycle to work scheme, car sharing and free campus buses from various locations around Cambridge. Equally important to campus life are the social activities offered by the Sports and Social Club. Whether it is a 'Burns night supper', the Mid-summer Ball or a quiz night, there are always opportunities to meet with people working across the organisation. Learning, development and networking are other important aspects of life on campus.  There are a range of scientific seminars with our own and invited speakers, scientific group meetings and skills development workshops. Our Benefits include:  Defined Benefit Pension Scheme, Group Income Protection, Healthcare scheme, Childcare Vouchers, Nursery and 25 days Annual Leave plus Bank Holidays. Please provide a CV and cover letter.  Shortlisting will take place during the week commencing the 27th October and candidates selected for interview will be required attend a telephone interview in the first instance. Closing date: 23rd October 2014


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