Job ID: 882359
Job date: 2017-01-08
End Date:
Company : Emory University School of Medicine Country : Role : Postdoc
Job date: 2017-01-08
End Date:
Company : Emory University School of Medicine Country : Role : Postdoc
Job Description:
Emory University’s “International Center for Malaria Research Education and Development (ICMRED)”, located within the School of Medicine, the Emory Vaccine Center and Yerkes Research Center, is seeking multiple postdoctoral research associates to join large systems biology consortia supported by the National Institutes of Health (NIH/NIAID) and the Defense Advanced Research Project's Agency (DARPA) to accomplish goals of the “Malaria Host-Pathogen Interaction Center" (MaHPIC, see http://systemsbiology.emory.edu) and the “Host Acute Models of Malaria to study Experimental Resilience" (HAMMER, see https://globalbiodefense.com/2016/05/25/darpa-brings-hammer-malaria/) projects, respectively. Malaria is a devastating infectious disease that afflicts several hundred million people annually in about 100 countries. The MaHPIC and HAMMER consortia study and model malaria infections longitudinally in non-human primates (NHPs), including blood, bone marrow and other tissue analyses (and cells therefrom), with the application of cutting-edge technologies and disciplines including telemetry, physiology, immunomics, high-content flow cytometry, epigenomics, transcriptomics, proteomics, metabolomics, lipidomics, histopathology, bioinformatics and mathematical modeling to deliver a dynamic, multi-angle integrated view of host-parasite interactions, immune responses, physiology and pathogenesis. Goals also include revealing new targets for intervention, including host-directed targets and strategies for developing therapies to improve human host resilience to infection. The research is both hypothesis driven and generating, and clinical, parasitological, immunological, molecular, cell biological, and biochemical skills and assays are also critical to validate research findings. Comparative studies involving human infections are also important and achieved through collaborations with scientists in malaria endemic countries. Some areas of focus include: -Analysis of multiple big data sets and time series, from longitudinal infections (by multiple Plasmodium species, and involving multiple primate host; NHPs and humans), and performing analyses and integration to seek omics correlates of clinical outcome and symptoms (e.g., degree of illness and disease severity) and mechanistic connections between different data types. -Analysis of the various high-throughput data with the goal of investigating the host biological networks activated by malaria parasites and simultaneously assessing changes in the parasite’s gene expression and biology. -Designing, implementing, and analyzing experiments focusing on host immunology and physiology in response to infection by malaria parasites. A major overarching goal of this work is to understand the host-pathogen infection processes and responses, and identify aspects that enable the host to be more or less resilient to disease outcomes due to the malaria parasite. DESIRED SKILLS AND EXPERIENCE Candidates with a combination of skills are sought, including disciplines such as biology, physiology, immunology, histopathology, pathogenesis, bioinformatics, and mathematical modeling. Applicants should possess strong scientific and/or computational skills, an affinity for hypothesis development and testing in a collaborative research environment, and a drive to learn new skills. Excellent communication, presentation and reporting skills are essential, as well as the ability to work independently and as a team player. A PhD in biological sciences, computational biology, bioinformatics, or a related computer science discipline is required. MD or DVM candidates with such skills may also be considered, particularly in the areas of systems biology, physiology, immunology and histopathology.
Additional Info:
The MaHPIC and HAMMER teams are highly collaborative, fast-paced, and deliverable-oriented, providing a learning environment with excellent working conditions, compensation, and career development opportunities for its team members. The positions will be based at Emory University, at multiple campus locations, and candidates are expected to work closely with team members as required at Emory, The Georgia Institute of Technology (GA Tech) and the University of Georgia in Athens (UGA), as well as other national and international institutions. Applicants should apply by sending a PDF containing a cover letter, a curriculum vitae, a personal statement (1 page) noting career goals, and the names and contacts of three references via the "Apply for this job" button. The application should include information on the suitability of the applicant for the open positions and stress the specific talents they will bring to this program. Multiple positions are available immediately. Applications will be considered until the positions are filled. Selected candidates will be interviewed by multiple faculty members from within the consortia. ABOUT THE EMPLOYER: Emory University provides excellent benefits and a rewarding work environment, with the advantage of being located in the major, thriving city of Atlanta, GA, USA. People are drawn to work here to enrich, change and save lives. They are attracted by the opportunity to participate in the community life of a top-ranked university. Emory ranks as the second-largest employer in the metro Atlanta area, with more than 29,300 people on the payroll as of Sept. 1, 2015. Emory University is an equal opportunity/equal access/affirmative action employer fully committed to achieving a diverse workforce and complies with all Federal and Georgia State laws, regulations, and executive orders regarding non-discrimination and affirmative action. Emory University does not discriminate on the basis of race, age, color, religion, national origin or ancestry, sex, gender, disability, veteran status, genetic information, sexual orientation, or gender identity or expression[Click Here to Access the Original Job Post]
Emory University’s “International Center for Malaria Research Education and Development (ICMRED)”, located within the School of Medicine, the Emory Vaccine Center and Yerkes Research Center, is seeking multiple postdoctoral research associates to join large systems biology consortia supported by the National Institutes of Health (NIH/NIAID) and the Defense Advanced Research Project's Agency (DARPA) to accomplish goals of the “Malaria Host-Pathogen Interaction Center" (MaHPIC, see http://systemsbiology.emory.edu) and the “Host Acute Models of Malaria to study Experimental Resilience" (HAMMER, see https://globalbiodefense.com/2016/05/25/darpa-brings-hammer-malaria/) projects, respectively. Malaria is a devastating infectious disease that afflicts several hundred million people annually in about 100 countries. The MaHPIC and HAMMER consortia study and model malaria infections longitudinally in non-human primates (NHPs), including blood, bone marrow and other tissue analyses (and cells therefrom), with the application of cutting-edge technologies and disciplines including telemetry, physiology, immunomics, high-content flow cytometry, epigenomics, transcriptomics, proteomics, metabolomics, lipidomics, histopathology, bioinformatics and mathematical modeling to deliver a dynamic, multi-angle integrated view of host-parasite interactions, immune responses, physiology and pathogenesis. Goals also include revealing new targets for intervention, including host-directed targets and strategies for developing therapies to improve human host resilience to infection. The research is both hypothesis driven and generating, and clinical, parasitological, immunological, molecular, cell biological, and biochemical skills and assays are also critical to validate research findings. Comparative studies involving human infections are also important and achieved through collaborations with scientists in malaria endemic countries. Some areas of focus include: -Analysis of multiple big data sets and time series, from longitudinal infections (by multiple Plasmodium species, and involving multiple primate host; NHPs and humans), and performing analyses and integration to seek omics correlates of clinical outcome and symptoms (e.g., degree of illness and disease severity) and mechanistic connections between different data types. -Analysis of the various high-throughput data with the goal of investigating the host biological networks activated by malaria parasites and simultaneously assessing changes in the parasite’s gene expression and biology. -Designing, implementing, and analyzing experiments focusing on host immunology and physiology in response to infection by malaria parasites. A major overarching goal of this work is to understand the host-pathogen infection processes and responses, and identify aspects that enable the host to be more or less resilient to disease outcomes due to the malaria parasite. DESIRED SKILLS AND EXPERIENCE Candidates with a combination of skills are sought, including disciplines such as biology, physiology, immunology, histopathology, pathogenesis, bioinformatics, and mathematical modeling. Applicants should possess strong scientific and/or computational skills, an affinity for hypothesis development and testing in a collaborative research environment, and a drive to learn new skills. Excellent communication, presentation and reporting skills are essential, as well as the ability to work independently and as a team player. A PhD in biological sciences, computational biology, bioinformatics, or a related computer science discipline is required. MD or DVM candidates with such skills may also be considered, particularly in the areas of systems biology, physiology, immunology and histopathology.
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Additional Info:
The MaHPIC and HAMMER teams are highly collaborative, fast-paced, and deliverable-oriented, providing a learning environment with excellent working conditions, compensation, and career development opportunities for its team members. The positions will be based at Emory University, at multiple campus locations, and candidates are expected to work closely with team members as required at Emory, The Georgia Institute of Technology (GA Tech) and the University of Georgia in Athens (UGA), as well as other national and international institutions. Applicants should apply by sending a PDF containing a cover letter, a curriculum vitae, a personal statement (1 page) noting career goals, and the names and contacts of three references via the "Apply for this job" button. The application should include information on the suitability of the applicant for the open positions and stress the specific talents they will bring to this program. Multiple positions are available immediately. Applications will be considered until the positions are filled. Selected candidates will be interviewed by multiple faculty members from within the consortia. ABOUT THE EMPLOYER: Emory University provides excellent benefits and a rewarding work environment, with the advantage of being located in the major, thriving city of Atlanta, GA, USA. People are drawn to work here to enrich, change and save lives. They are attracted by the opportunity to participate in the community life of a top-ranked university. Emory ranks as the second-largest employer in the metro Atlanta area, with more than 29,300 people on the payroll as of Sept. 1, 2015. Emory University is an equal opportunity/equal access/affirmative action employer fully committed to achieving a diverse workforce and complies with all Federal and Georgia State laws, regulations, and executive orders regarding non-discrimination and affirmative action. Emory University does not discriminate on the basis of race, age, color, religion, national origin or ancestry, sex, gender, disability, veteran status, genetic information, sexual orientation, or gender identity or expression[Click Here to Access the Original Job Post]