Job Description:
A postdoc position for a fixed term of three years for high-dimensional single cell analysis of natural killer cell repertoires at K.G. Jebsen Center for Cancer Immunotherapy. We are looking for a highly motivated PhD with a strong background in bioinformatics/computational biology. The project concerns the mechanisms underlying the functional diversification of human natural killer cells. Studies of immunological diversity in populations are combined with the integration and analysis of high-dimensional single-cell data generated by RNASeq, flow cytometry and CyTOF. The candidate will work at the interface of immunology, cancer and bioinformatics. Immune informatics is a nascent field with many challenging computational tasks ahead. The candidate, together with colleagues, will particularly focus on computational approaches toward clinically relevant immune profiling of immune-cell repertoires in patients. Depending on qualifications of the applicant, the position may offer the possibility to develop an independent line of research within the overall scope of the groups research program. The Institute for Cancer Research and the Institute of Clinical Medicine The Institute for Cancer Research, Oslo University Hospital, and Institute of Clinical Medicine, University of Oslo, (http://ous-research.no/institute/) hosts core facilities for multiparameter flow cytometery, CyTOF, next generation sequencing, imaging and bioinformatics. The Comprehensive Cancer Center (CCC) of OUHRadiumhospitalet, is one of the largest Cancer Centers in Europe with its own Phase I/II clinical trial unit and one of the leading European academic facilities for good manufacturing practices (GMP) production of cells for immunotherapy. These units integrate clinical departments with the Dept. of Immunology, giving OUH a competitive edge in bringing “in-house” discoveries to early clinical trials. Building on a long tradition of investigator-initiated trials, the group is currently developing a new strategy for selective and controlled expansion of educated NK cells for cancer therapy. K.G. Jebsen Center for Cancer Immunotherapy Malmberg is the co-director of the K.G. Jebsen Center for Cancer Immunotherapy (JCIT) (http://www.med.uio.no/klinmed/english/research/centres/kgj-cancer-immunotherapy/), which is a new virtual research center awarded funding by the Kristian Gerhard Jebsen Foundation and the University of Oslo. The center comprises the research groups of 6 principal investigators, of which 5 are located within the UiO/Oslo University Hospital Medical Campus, and one partner is located at the Netherlands Cancer Institute. The research environment is highly dynamic with extensive interaction between the groups. Eligibility and Qualifications The candidate must have a PhD in bioinformatics or computational biology equivalent to a Norwegian doctoral degree in Medicine/Life sciences. Successful applicants must have obtained their degree prior to taking on the position. Candidates should have a strong, documented background in bioinformatics/computational biology. Competence within a relevant high level programming language is necessary. Previous experience in immunological research is preferable. In connection with the appointment of the post-doctoral position, we will accord special weight to academic skills; particularly demonstrated excellence in research, a strong dedication and excellent communication skills. We are looking for a Researcher who has:
Additional Info:
[Click Here to Access the Original Job Post]
A postdoc position for a fixed term of three years for high-dimensional single cell analysis of natural killer cell repertoires at K.G. Jebsen Center for Cancer Immunotherapy. We are looking for a highly motivated PhD with a strong background in bioinformatics/computational biology. The project concerns the mechanisms underlying the functional diversification of human natural killer cells. Studies of immunological diversity in populations are combined with the integration and analysis of high-dimensional single-cell data generated by RNASeq, flow cytometry and CyTOF. The candidate will work at the interface of immunology, cancer and bioinformatics. Immune informatics is a nascent field with many challenging computational tasks ahead. The candidate, together with colleagues, will particularly focus on computational approaches toward clinically relevant immune profiling of immune-cell repertoires in patients. Depending on qualifications of the applicant, the position may offer the possibility to develop an independent line of research within the overall scope of the groups research program. The Institute for Cancer Research and the Institute of Clinical Medicine The Institute for Cancer Research, Oslo University Hospital, and Institute of Clinical Medicine, University of Oslo, (http://ous-research.no/institute/) hosts core facilities for multiparameter flow cytometery, CyTOF, next generation sequencing, imaging and bioinformatics. The Comprehensive Cancer Center (CCC) of OUHRadiumhospitalet, is one of the largest Cancer Centers in Europe with its own Phase I/II clinical trial unit and one of the leading European academic facilities for good manufacturing practices (GMP) production of cells for immunotherapy. These units integrate clinical departments with the Dept. of Immunology, giving OUH a competitive edge in bringing “in-house” discoveries to early clinical trials. Building on a long tradition of investigator-initiated trials, the group is currently developing a new strategy for selective and controlled expansion of educated NK cells for cancer therapy. K.G. Jebsen Center for Cancer Immunotherapy Malmberg is the co-director of the K.G. Jebsen Center for Cancer Immunotherapy (JCIT) (http://www.med.uio.no/klinmed/english/research/centres/kgj-cancer-immunotherapy/), which is a new virtual research center awarded funding by the Kristian Gerhard Jebsen Foundation and the University of Oslo. The center comprises the research groups of 6 principal investigators, of which 5 are located within the UiO/Oslo University Hospital Medical Campus, and one partner is located at the Netherlands Cancer Institute. The research environment is highly dynamic with extensive interaction between the groups. Eligibility and Qualifications The candidate must have a PhD in bioinformatics or computational biology equivalent to a Norwegian doctoral degree in Medicine/Life sciences. Successful applicants must have obtained their degree prior to taking on the position. Candidates should have a strong, documented background in bioinformatics/computational biology. Competence within a relevant high level programming language is necessary. Previous experience in immunological research is preferable. In connection with the appointment of the post-doctoral position, we will accord special weight to academic skills; particularly demonstrated excellence in research, a strong dedication and excellent communication skills. We are looking for a Researcher who has:
- High working capacity
- Strong motivation and interest in solving biological problems
- Ability to design, plan, interpret original experiments in an independent and innovative manner
- Excellent oral and written communication skills in English The main purpose of post-doctoral research fellowships is to qualify researchers for work in top academic positions within their disciplines.
- A challenging and friendly international working environment with broad expertise in immunology and bioinformatics.
- Access to state of the art facilities and resources for biomedical research.
- Affiliation to the newly inaugurated KG Jebsen Center for Cancer Immunotherapy.
- These positions will be placed as SKO 1352 – Postdoc fellow with salary range depending on qualifications: step 57 – 65 (NOK 483 700 – 560 700).
- favorable welfare and pension arrangements.
- Motivation and research plans (max 2 pages)
- CV (summarizing education, employments within and/or outside of academia)
- List of publications and academic work that the applicant wishes to be considered by the evaluation committee (not complete articles)
- Copies of educational certificates and relevant grades
- Names, email and telephone number of 2-3 referees (describe relation to applicant)
- The application with attachments should be a single pdf file that includes a covering letter summarizing all of these items. The application with all attachments must be submitted via our electronic recruitment system EasyCruit.
Requeriments :
Skills :
Areas :
Additional Info:
[Click Here to Access the Original Job Post]