Job Description:
A postdoctoral position will be available at IBM, Zurich Research Laboratory, starting March 2015 to work on the interdisciplinary project ‘Breast cancer metastasiX: Mathematical modeling of tumor heterogeneity during progression to metastases and clinical validation’. This project is integrated within a collaborative effort that gathers clinicians, biologist, computational scientists, etc as well as academic and industrial partners.
Each year 1.4 million cases of breast cancer will occur among women worldwide and 450,000 women will die from this disease, mostly due to metastasis. This consortium aims at understanding the quantitative behavior of breast cancer growth and progression to metastasis. The predominant goal is to use a systems biology approach to unravel, integrate and mathematically model the cellular and molecular determinants of breast cancer metastasis.
The successful candidate will analyze single-cell data (mass-cytometry and RNA-Seq) and develop mathematical and statistical models that can unravel the regulatory signaling networks that are active at different stages of tumor progression and for different tumor subpopulations. One of the challenges of such analysis involves the deconvolution of the different molecular signatures that arise from the cell populations that are present in any given tumor. While reconstructing the network for every sorted subpopulation separately is one (straightforward) possibility, the project will also aim at developing an inference setup where the whole heterogeneous population can be considered at once.
Interested candidates, please send an application including CV and 3 reference letters to: Dr. Maria Rodriguez Martinez .
Keywords: Statistical inference, Machine Learning, Single-cell data, Genomics, Proteomics.
Candidates should have a strong background in computer science, statistical inference, mathematics or physics and be interested in cancer-related research. Strong programming skills are necessary. Experience in machine learning, big data analysis, and high performance computing would be a plus. Previous experience in genomics would be helpful but not essential.
--------------------------------------------------------------------------------
Job Information
Position Type: Post-Doctoral Research Fellowships
Start Date: March 01, 2014
Duration: Full Time
Status: open
--------------------------------------------------------------------------------
Contact Information
IBM - Zurich Research Laboratory
Maria Rodriguez Martinez
mrm@zurich.ibm.com
How To Apply:
email
Additional Info:
[Click Here to Access the Original Job Post]
A postdoctoral position will be available at IBM, Zurich Research Laboratory, starting March 2015 to work on the interdisciplinary project ‘Breast cancer metastasiX: Mathematical modeling of tumor heterogeneity during progression to metastases and clinical validation’. This project is integrated within a collaborative effort that gathers clinicians, biologist, computational scientists, etc as well as academic and industrial partners.
Each year 1.4 million cases of breast cancer will occur among women worldwide and 450,000 women will die from this disease, mostly due to metastasis. This consortium aims at understanding the quantitative behavior of breast cancer growth and progression to metastasis. The predominant goal is to use a systems biology approach to unravel, integrate and mathematically model the cellular and molecular determinants of breast cancer metastasis.
The successful candidate will analyze single-cell data (mass-cytometry and RNA-Seq) and develop mathematical and statistical models that can unravel the regulatory signaling networks that are active at different stages of tumor progression and for different tumor subpopulations. One of the challenges of such analysis involves the deconvolution of the different molecular signatures that arise from the cell populations that are present in any given tumor. While reconstructing the network for every sorted subpopulation separately is one (straightforward) possibility, the project will also aim at developing an inference setup where the whole heterogeneous population can be considered at once.
Interested candidates, please send an application including CV and 3 reference letters to: Dr. Maria Rodriguez Martinez .
Keywords: Statistical inference, Machine Learning, Single-cell data, Genomics, Proteomics.
Candidates should have a strong background in computer science, statistical inference, mathematics or physics and be interested in cancer-related research. Strong programming skills are necessary. Experience in machine learning, big data analysis, and high performance computing would be a plus. Previous experience in genomics would be helpful but not essential.
--------------------------------------------------------------------------------
Job Information
Position Type: Post-Doctoral Research Fellowships
Start Date: March 01, 2014
Duration: Full Time
Status: open
--------------------------------------------------------------------------------
Contact Information
IBM - Zurich Research Laboratory
Maria Rodriguez Martinez
mrm@zurich.ibm.com
How To Apply:
Requeriments :
Skills :
Areas :
Additional Info:
[Click Here to Access the Original Job Post]