Job Description:
The Department of Physiology, Anatomy and Genetics (DPAG) are seeking to appoint a bioinformatician, for a postdoctoral research assistant to join a highly-motivated biotechnology team. The project is funded by OxStem (www.oxstem.co.uk) a revolutionary spin-out company from the University of Oxford, founded by Professor Steve Davies, Professor Dame Kay Davies and Professor Angela Russell, which raised a record-breaking £16.9M in its initial funding round last year. The company is a developer of cell activation therapies with a unique approach to regenerative medicine, aiming to develop small molecules that can activate repair mechanisms that already exist within the body. OxStem is leading the field into a new era of small molecule-driven stem cell activation that will be transformative for healthcare. OxStem is seeking bioinformatics support from an experienced candidate, to work across the four subsidiary companies: OxStem Oncology, OxStem Neuro, OxStem Ocular, OxStem Cardio. The candidate will be joining the team primarily to engage in genomic and transcriptomic analyses of ‘before’ and ‘after’ drug dosing regimens in human and mouse primary cells and cell lines. The candidate would be embedded in the bioinformatics research team of Professor Caleb Webber, amongst other informaticians applying cutting-edge gene networking approaches to the analyses of genomic, transcriptomic and proteomic data across a range of biomedical problems. We would be willing to consider candidates who have extensive computational or statistical expertise in areas other than gene expression analysis. Your duties will include analysing a range of Omics data from projects across OxStem-funded programmes and effectively communicating results with other members of the project team. You will contribute to experimental design and planning of Omics projects across OxStem-funded programmes. You will manage your own academic research and administrative activities. This involves small scale project management and co-ordinating multiple aspects of work to meet deadlines. You will contribute ideas for new research projects, develop ideas for generating research income, and present detailed research proposals to senior researchers. This post will require you to collaborate in the preparation of scientific reports and journal articles and occasionally present papers and posters. You will act as a source of information and advice to other members of the group on scientific protocols and experimental techniques and also represent the research group at external meetings/seminars, either with other members of the group or alone. You will have, or be working towards completion of a PhD/DPhil in bioinformatics or a related subject (e.g. computer science, informatics, biostatistics) with a demonstrated interest in application to molecular biology. You will have strong analytical skills, including, but not limited to: read mapping and data visualisation skills, including dimensionality reduction approaches (e.g. PCA, t-SNE), differential gene expression analysis from RNA sequencing data using DESeq2, edgeR or similar bioinformatics tools, comparison of published datasets, pathway and functional analyses. You will have expertise in statistical analyses and in the relevant aspects of experimental design. You will be motivated and engaged with the wider aim of OxStem-funded projects and have the ability to engage with wet lab researchers in each of the OxStem-funded projects to help develop appropriate bioinformatics analysis pipelines. This post requires you to also have good teaching skills and an ability to teach wet lab researchers how to run basic analysis pipelines. The post is initially funded until 2 May 2019 and you will be based in the Oxford Centre for Gene Function, Parks Road, Oxford OX1 3PT. The closing date for applications is 12.00 noon on Wednesday 1 November 2017.
Additional Info:
Salary: Grade 7: £31,604 - £38,833 p.a. Please note that the University of Oxford's retirement policy is changing. With effect from October 1 2017, all employees at Grade 8 and above will have a retirement age of 68, and all employees at Grades 6 and 7 will no longer have a set retirement age. Further details are available at: www.ox.ac.uk/about/jobs/preemploymentscreening.[Click Here to Access the Original Job Post]
The Department of Physiology, Anatomy and Genetics (DPAG) are seeking to appoint a bioinformatician, for a postdoctoral research assistant to join a highly-motivated biotechnology team. The project is funded by OxStem (www.oxstem.co.uk) a revolutionary spin-out company from the University of Oxford, founded by Professor Steve Davies, Professor Dame Kay Davies and Professor Angela Russell, which raised a record-breaking £16.9M in its initial funding round last year. The company is a developer of cell activation therapies with a unique approach to regenerative medicine, aiming to develop small molecules that can activate repair mechanisms that already exist within the body. OxStem is leading the field into a new era of small molecule-driven stem cell activation that will be transformative for healthcare. OxStem is seeking bioinformatics support from an experienced candidate, to work across the four subsidiary companies: OxStem Oncology, OxStem Neuro, OxStem Ocular, OxStem Cardio. The candidate will be joining the team primarily to engage in genomic and transcriptomic analyses of ‘before’ and ‘after’ drug dosing regimens in human and mouse primary cells and cell lines. The candidate would be embedded in the bioinformatics research team of Professor Caleb Webber, amongst other informaticians applying cutting-edge gene networking approaches to the analyses of genomic, transcriptomic and proteomic data across a range of biomedical problems. We would be willing to consider candidates who have extensive computational or statistical expertise in areas other than gene expression analysis. Your duties will include analysing a range of Omics data from projects across OxStem-funded programmes and effectively communicating results with other members of the project team. You will contribute to experimental design and planning of Omics projects across OxStem-funded programmes. You will manage your own academic research and administrative activities. This involves small scale project management and co-ordinating multiple aspects of work to meet deadlines. You will contribute ideas for new research projects, develop ideas for generating research income, and present detailed research proposals to senior researchers. This post will require you to collaborate in the preparation of scientific reports and journal articles and occasionally present papers and posters. You will act as a source of information and advice to other members of the group on scientific protocols and experimental techniques and also represent the research group at external meetings/seminars, either with other members of the group or alone. You will have, or be working towards completion of a PhD/DPhil in bioinformatics or a related subject (e.g. computer science, informatics, biostatistics) with a demonstrated interest in application to molecular biology. You will have strong analytical skills, including, but not limited to: read mapping and data visualisation skills, including dimensionality reduction approaches (e.g. PCA, t-SNE), differential gene expression analysis from RNA sequencing data using DESeq2, edgeR or similar bioinformatics tools, comparison of published datasets, pathway and functional analyses. You will have expertise in statistical analyses and in the relevant aspects of experimental design. You will be motivated and engaged with the wider aim of OxStem-funded projects and have the ability to engage with wet lab researchers in each of the OxStem-funded projects to help develop appropriate bioinformatics analysis pipelines. This post requires you to also have good teaching skills and an ability to teach wet lab researchers how to run basic analysis pipelines. The post is initially funded until 2 May 2019 and you will be based in the Oxford Centre for Gene Function, Parks Road, Oxford OX1 3PT. The closing date for applications is 12.00 noon on Wednesday 1 November 2017.
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Additional Info:
Salary: Grade 7: £31,604 - £38,833 p.a. Please note that the University of Oxford's retirement policy is changing. With effect from October 1 2017, all employees at Grade 8 and above will have a retirement age of 68, and all employees at Grades 6 and 7 will no longer have a set retirement age. Further details are available at: www.ox.ac.uk/about/jobs/preemploymentscreening.[Click Here to Access the Original Job Post]